@colleennoviello.bsky.social
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reposted by
Dr. Jonathan N. Stea
about 1 year ago
RFK Jr and Statistics:
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This is insane:
grants.nih.gov/grants/guide...
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NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-068.html
over 1 year ago
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With the crazy fires all around, I neglected to highlight the incredible story, led by our post-doc Jia Zhou, on native GABA-A receptors!! Truly a heroic effort!!!
www.nature.com/articles/s41...
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Resolving native GABAA receptor structures from the human brain - Nature
Cryo-electron microscopy structures of native type A GABA receptors from human brain reveal diverse subunit compositions, protein binding partners and binding sites for antiepileptic drugs.
https://www.nature.com/articles/s41586-024-08454-1
over 1 year ago
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Pretty excited about this work looking at high-resolution mechanisms involved in the autoimmune disease myasthenia gravis! Please read our pre-print :D
www.biorxiv.org/content/10.1...
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Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures
Skeletal muscle contraction is mediated by acetylcholine (ACh) binding to its ionotropic receptors (AChRs) at neuromuscular junctions. In myasthenia gravis (MG), autoantibodies target AChRs, disruptin...
https://www.biorxiv.org/content/10.1101/2024.12.18.629229v1
over 1 year ago
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reposted by
Bodega Cats
over 1 year ago
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