@colleennoviello.bsky.social
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reposted by
Dr. Jonathan N. Stea
5 months ago
RFK Jr and Statistics:
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This is insane:
grants.nih.gov/grants/guide...
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NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-068.html
8 months ago
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With the crazy fires all around, I neglected to highlight the incredible story, led by our post-doc Jia Zhou, on native GABA-A receptors!! Truly a heroic effort!!!
www.nature.com/articles/s41...
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Resolving native GABAA receptor structures from the human brain - Nature
Cryo-electron microscopy structures of native type A GABA receptors from human brain reveal diverse subunit compositions, protein binding partners and binding sites for antiepileptic drugs.
https://www.nature.com/articles/s41586-024-08454-1
8 months ago
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Pretty excited about this work looking at high-resolution mechanisms involved in the autoimmune disease myasthenia gravis! Please read our pre-print :D
www.biorxiv.org/content/10.1...
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Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures
Skeletal muscle contraction is mediated by acetylcholine (ACh) binding to its ionotropic receptors (AChRs) at neuromuscular junctions. In myasthenia gravis (MG), autoantibodies target AChRs, disruptin...
https://www.biorxiv.org/content/10.1101/2024.12.18.629229v1
9 months ago
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reposted by
Bodega Cats
10 months ago
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