1/ 🔬 Our work, "Dynamic transitions of initiator binding coordinate the replication of the two chromosomes in Vibrio cholerae", is now published in Nature Communications. Here's a thread on how we think Chr1 and Chr2 replication is coordinated in Vibrio. 🧵 Link : www.nature.com/articles/s41...

Kudos to Justine Collier, Florian Fournés, and the others biorxiv.org/content/10.1... GREAT DISCOVERY : Agrobacterium controls its 2 chromosomes replication timing similarly to cholerae but with a COMPLETELY DIFFERENT SETUP.

I am particularly proud of this study from our laboratory, which explains how integrons have set up a kind of second-order selection. It reminds me of the time of the papiers on the selection of mutators to resist ABs. @FrancoisTaddei, Miro, Ivan, Jesus... www.science.org/doi/10.1126/...