Lucía Barbadilla Martínez
@luciabarmar.bsky.social
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PhD student. Studying gene regulation using AI models | UMCU + NKI, The Netherlands
reposted by
Lucía Barbadilla Martínez
Žiga Avsec
5 months ago
Excited to launch our AlphaGenome API
goo.gle/3ZPUeFX
along with the preprint
goo.gle/45AkUyc
describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind
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reposted by
Lucía Barbadilla Martínez
Cell Reports
6 months ago
Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification
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Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification
Guerin et al. present a highly resolved timeline of chromatin and DNA methylation dynamics during early neural progenitor cell differentiation. Their approach demonstrates that chromatin and DNA methylation mechanisms operate on different timescales to mediate short- and long-term gene enhancer regulation.
http://dlvr.it/TKmS7R
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Our review "Predicting gene expression from DNA sequence using deep learning models" is finally out! 🤗
add a skeleton here at some point
6 months ago
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you reached the end!!
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