Nan Xu (@nanxu4.bsky.social)

💫NEW: @studerl.bsky.social , Ciceri & co present a whole-genome CRISPR-Cas9 knockout screen using directed differentiation systems. They find that MEN1 and SUZ12 modulate human developmental timing by epigenetically controlling bivalent promoters of developmental genes. bit.ly/4m4YKsx

loading . . .

Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing - Nature Cell Biology Xu et al. perform a whole-genome CRISPR-Cas9 knockout screen using directed differentiation systems. They find that MEN1 and SUZ12 modulate human developmental timing by epigenetically controlling biv... https://bit.ly/4m4YKsx