New pipeline version finally out now! 🥳

🧬🖥️So excited to show you the outcome of @pascivers.bsky.social and my latest project: "From Hype to Health Check: Critical Evaluation of Drug Response Prediction Models with DrEval" doi.org/10.1101/2025.05.26.655288, published with M. Picciani, M. Wilhelm, K. Baum & @itisalist.bsky.social. 🧵1/10

@lisiarend.bsky.social, @quirinmanz.bsky.social, Kilian Kirmes, and I just created a nice overview of a typical CyTOF experiment using BioRender - now also available there as a template - and on Wikipedia! 🎨✨ Check it out and feel free to use it! en.wikipedia.org/wiki/CyTOF

🧬🖥️ Proud to share our latest update on PPI predictions – "Deep learning models for unbiased sequence-based PPI prediction plateau at an accuracy of 0.65" doi.org/10.1101/2025... by T. Reim, published with @itisalist.bsky.social @dbblumenthal.bsky.social, A. Hartebrodt, and me. What did we do? 1/15 🧵

🧬🖥️Tranferring my papers, Pt. 2: "Guiding questions to avoid data leakage in biological machine learning applications" doi.org/10.1038/s41592-024-02362-y, which I published with @itisalist.bsky.social @dbblumenthal.bsky.social @romanjoeres.bsky.social, D. Grimm, F. Haselbeck, and O.V. Kalinina. 🧵1/20

Update: Since we published "Cracking the black box of deep sequence-based protein-protein interaction prediction," we have received mostly positive feedback. I presented our work at multiple conferences, including the ISMB/ECCB23 and GCB23. 🧬🖥️ doi.org/10.1093/bib/...

🧬💻Transferring my paper posts here, starting off with "Cracking the black box of deep sequence-based protein-protein interaction prediction" doi.org/10.1093/bib/..., which I published together with @itisalist.bsky.social and @dbblumenthal.bsky.social. So what was it about? 1/13 🧵

Had great fun attending the #gcb2024 in Bielefeld. Our group had the honor of contributing 2 talks (Judith Bernett on guiding questions to avoid data leakage and Johannes Kersting on GRN inference with DysRegNet. A surprise at the end: Alex Dietrich won the poster prize with the project omnideconv!