A little R&R at a great treehouse (truly a treehouse) in White Salmon for a couple of days. Coffee and a beautiful view of Mt. Adams this morning.

In 2012 I received a $50k grant from the Murdock Foundation to build our computer cluster Genome that @jcatchen.bsky.social helped me build. After years of faithful service, dozens of papers and countless trainees using it we flipped the main power off to it for the last time.

Visit to OSU for a grad student defense and ran into a familiar face in the stairwell of Nash Hall!

Spaceflight Started 100 Years Ago in a Massachusetts Cabbage Patch www.nytimes.com/2026/03/16/s...

snputils (snputils.org): A High-Performance Python Library for Genetic Variation and Population Structure www.biorxiv.org/content/10.6... 🧬💻🧪 github.com/AI-sandbox/s...

Oregon Battle of the Books (OBOB). Hundreds of kids ready to match their reading chops. So cool.

Nice talk in the IE2 seminar series at UO about carbon in soils by @katerinageorgiou.bsky.social from Oregon State.

SSE is pleased to offer free virtual #Evol2026 registration to all SSE members residing in 152 countries and territories around the world including India, Brazil, Mexico, and Colombia. Request your free registration code today! www.evolutionsociety.org/index.php?mo...

Nominations are open to the annual 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗘𝗰𝗼𝗹𝗼𝗴𝘆 𝗣𝗿𝗶𝘇𝗲! The award recognizes the work of outstanding scientists for their contribution to the field of molecular ecology. Nominations are due on 𝟮𝟰 𝗔𝗽𝗿𝗶𝗹 𝟮𝟬𝟮𝟲. Read more: onlinelibrary.wiley.com/page/journal...

My awesome colleague, @yarimura.bsky.social, is recruiting a postdoc to start at the end of 2026 or early 2027! His lab uses cryo-EM to uncover structural basis of key chromatin events using native complexes isolated from human cells or Xenopus egg extracts! careers-fhcrc.icims.com/jobs/30706/p...

I was sad to learn that my postdoctoral mentor, David Botstein, died yesterday. I started with David as a postdoc in 1998, and he had a profound effect on both my life and scientific career. He was a giant in the field of genetics, making seminal contributions in both yeast and human genetics. 1/

We are all Claude.

Shakshuka.

Several thousand patriots speaking up and protesting peacefully in downtown Eugene.

📡🧵 Excited to release an updated version of our preprint: Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish Embryogenesis 🧪🧬🖥️🐠 doi.org/10.1101/2024... A tour-de-force by @yangjoonkim with an unexpected discovery!

PEQG! My favorite conference ever*. Single session, fantastic talks, great discussions. Only once every 2 years. And in the best conference location too! Abstract deadline coming up Feb 5! *Disclosure: I am required to say it's the best conference because it is and I told my mom I wouldn't lie.

Yum

I love when the prep is all done for dinner and everything is laid out and ready to go. Oregon sole with olives and rosemary and garlic and wild rice.

Cool bay pipefish exhibit at the Oregon Coast Aquarium in Newport Oregon.

🎁 gift link to #science funding article about cuts to research grants 🧪🧬🔬🔭🥼

“Fundamentally, the premise of the document is inconsistent with our core belief that scientific funding should be based on scientific merit alone,” Dr. Kornbluth wrote. Follow the lead the rest of you.

Excellent piece from a former NIH colleague and #BethesdaDeclaration co-signer. She highlights the ongoing censorship at NIH and calls for the following three actions: www.nature.com/articles/d41...

Mmm- I asked in my browser what one dollar of Apple stock purchased in 1999 would be worth today. The AI answer - “ If you had $1 in Apple stock bought in 1999, it would be worth approximately $1.04 trillion today based on the average annual growth rate of Apple's stock” real answer ~ $160

Holy cow this was an amazing race at Hayward at @uoregon.bsky.social He started running 3 years ago — as a 7th grader - and now owns the U16 and U18 world records and I think the 18th fastest 800 of all time by anyone. He starts 12th grade in the Fall. www.runnersworld.com/news/a655851...

Thanks everyone, it’s been fun being a scientist in the US. 👋

I always find survey results like this staggering (almost to the point of unbelievability). The US was spending around 1% of its federal budget on foreign aid. The average guess among 1,000+ surveyed Americans was 26%. 15% thought it was over half of the budget (?!) www.kff.org/global-healt...

SCOOP www.importantcontext.news/p/national-s...

The "unitary executive theory" is a fancy name for a strategy used by authoritarians worldwide, rebranded for the US. It’s a legal blueprint for a power grab, and my new article explains how it turns the law itself into a tool for undermining democracy:

Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment www.nytimes.com/2025/07/07/s...

Reflecting on how lucky I am to have watched hands the best women’s 5k of ever yesterday. Beatrice Chebet breaks the world record and is the first woman under 14min. And Ngetich and Tsegay are right there with what would have been world records only recently. And Chebet’s beautiful and awesome kick.

50th anniversary Pre meet about to kick off. Awesome.

So irresponsible and cruel. The bill in the Senate will take money and healthcare from poor and middle class Americans to pay for even more tax breaks to the rich and to pile more debt on our children (and us frankly). It’s important to provide a clear message about the truth of what is happening.

🧪 If you live in these States and care about biomedical research and the #NIH, please call your Senators: Maine (Collins) West Virginia (Capito) Louisiana (Cassidy) Alabama (Britt) Pennsylvania (McCormick) 👇👇👇👇👇👇👇

At the cabin for a little Solstice fix up work. And it’s snowing. Big, wet Summer Solstice flakes.

Any leads would be appreciated 🙏

The perfect Father’s Day gift from my daughter- a tee shirt of the setting of the two suns of Tatooine. Nice.

11,000,000+ at the No King Protests. We hit the 3.5% rule!!! The "3.5% rule" states that no government has been able to withstand a challenge from a nonviolent movement that mobilizes 3.5% of its population. Way to go United States!!! You understood the assignment!!! 🥳🥳🥳

This is what democracy looks like. Thousands and thousands of us in downtown Eugene.

Full on circus now. I need some popcorn.

Ah, Americans. We’re a classy bunch aren’t we.

🧪🌎

Just published, expansion in situ genome sequencing, where you can sequence DNA while still inside the cell, mapping its organization relative to proteins and other markers, with the help of expansion microscopy! Led by @jbuenrostro.bksy.social. www.science.org/doi/10.1126/...

A lot of really great resources here to #saveNSF 🧪 www.savensf.com/take-action

highlighting the importance of federally funded research and development to the development of biotech. Senator Young wrote this oped about the importance of federally funded research and development in academia, indicating his responsiveness to these arguments www.young.senate.gov/newsroom/pre...

US Scientists->proposed rule will allow gov to involuntarily move civil servants to a new category without protections from politicized firings- would allow YOUR PO to be replaced with political appointee. YOUR comments can help-here's how-by May 23 🧑‍🔬🧪🖥️🧬 www.ifyoucankeepit.org/i/162500841/...

Penny wise and pound foolish. “ …. government investments in research and development accounted for at least a fifth of U.S. productivity growth since World War II. “ www.nytimes.com/2025/04/30/b...

Our Nature paper (rdcu.be/ei1NM) deep sequencing a 4-generation, 28-member family using multiple sequencing technologies to study transmission of all classes of genetic variation is out! @uwgenome.bsky.social @hhmi.org @pacbio.bsky.social @utah.edu