Liver/Intestinal Community of Practice - AST (@ast-licop.bsky.social)

MAP >65 mmHg VS higher targets to improve AKI post LT 💫 LIVER-PAM trial 📌 open-label, single-center, RCT 📌 174 adult pts randomized to MAP 85-90 mmHg or 65-70 mmHg first 24 hrs 📌 primary outcome: AKI incidence within 7 days 🔑 Did not reduce AKI incidence #liversky pubmed.ncbi.nlm.nih.gov/40774358/

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Higher versus Standard Mean Arterial Pressure Target in the Immediate Postoperative Period of Liver Transplantation to Prevent Acute Kidney Injury: A Randomized Clinical Trial - (LIVER-PAM) - PubMed Acute kidney injury (AKI) is a frequent complication after liver transplantation, with incidence up to 81%, and is associated with impaired long-term renal function, graft survival, and increased mort... https://pubmed.ncbi.nlm.nih.gov/40774358/