April Kim
@aprilkim.bsky.social
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CS PhD student in the Battle Lab at JHU
reposted by
April Kim
Josh Weinstock
4 months ago
Really excited to share our new PRS method, developed with
@aprilkim.bsky.social
and
@alexisbattle.bsky.social
! Our approach is to use a lot of recently developed functional annotations to better estimate the weights of the SNPs.
www.medrxiv.org/content/10.1...
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Polygenic prediction of phenotypes with a neural empirical Bayes approach
Polygenic risk scores (PRS) estimate the expected value of a phenotype based on individual genotypes. Although statistical approaches for calculating PRS have advanced considerably in recent years, fe...
https://www.medrxiv.org/content/10.1101/2025.07.21.25331918v1
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