A chronotherapy study in Nature Medicine showed dramatic results. Then it was retracted. The phase III trial claimed a staggering boost to OS and PFS when immunochemotherapy was given before 3 p.m. https://cancerletter.com/news-analysis/20260710_1/

OMB’s plan to increase political control of science faces stiff opposition on Capitol Hill https://cancerletter.com/capitol-hill/20260710_2/

"With the benefit of experience, however, it has become clear that a screening strategy centered almost exclusively on colonoscopy is increasingly misaligned with today’s public health realities," writes Paul J. Limburg, MD, MPH. https://cancerletter.com/trials-and-tribulations/20260702_3/

Jenna Scott was 29, seven months pregnant, and suddenly, feeling very sick. One year later, in June 2017, shortly after her son turned one, Scott was diagnosed with stage 4 colon cancer. (@americancancersoc.bsky.social) https://cancerletter.com/clinical/20260702_1/

“Maura began making major impactful contributions while still in training. She totally changed our understanding of the etiology of head and neck cancer and demonstrated that one person can make a difference." - Otis Brawley, MD. @mdanderson.bsky.social https://cancerletter.com/obituary/20260702_2/

Northwell Cancer Institute opens $5.8M radiation center in Queens https://cancerletter.com/in-brief/20260702_6b/

Thymus may help prepare CD8+ T cells for rapid response before circulation, @mayoclinic.org study suggests https://cancerletter.com/clinical-roundup/20260702_7d/

FDA allows ZYN nicotine pouches to make marketing claim: ZYN is safer than cigarettes https://cancerletter.com/cancer-policy/20260702_5d/

"It really gives us pause when we see a young person with no known risk factors who's otherwise completely healthy present with advanced stage colorectal cancer, and that includes pregnant women," says Jennifer Davids, MD. @americancancersoc.bsky.social https://cancerletter.com/clinical/20260702_1/

FDA approves expanded use of Casgevy for pediatric sickle cell disease or transfusion-dependent beta thalassemia https://cancerletter.com/drugs-and-targets/20260702_8d/

Paul J. Limburg, MD, MPH: "I performed my first colonoscopy as a board-certified gastroenterologist more than 20 years ago, at a time when the procedure was firmly established as the “gold standard” for colorectal cancer screening." https://cancerletter.com/trials-and-tribulations/20260702_3/

David Gius assumes role of director of the University of Cincinnati Cancer Center https://cancerletter.com/in-brief/20260702_6a/

UTSW study shows how RNA-modifying enzyme linked to cancer picks its targets https://cancerletter.com/clinical-roundup/20260702_7c/

AmirAli Talasaz, PhD, writes, "One in three eligible Americans—over 50 million people—remain unscreened despite established methods like colonoscopy or stool-based tests existing for decades." https://cancerletter.com/news-analysis/20260619_4/

FDA approves Tregzi for chronic graft-versus-host disease https://cancerletter.com/drugs-and-targets/20260702_8c/

Visa delays continue as residency programs begin (@ameracadpeds.bsky.social, @acog.org) https://cancerletter.com/cancer-policy/20260702_5c/

Gillison, a professor of medicine, thoracic head and neck medical oncology at the University of Texas MD Anderson Cancer Center, was 61. @mdanderson.bsky.social https://cancerletter.com/obituary/20260702_2/

"His pioneering work directly led to the founding of a field dedicated to the search for cancer susceptibility genes, which now number over 120 distinct genes." - Stephen J. Chanock writes about Joe Fraumeni, MD. https://cancerletter.com/obituary/20260626_3/

FDA approves Trodelvy for first-line treatment of mTNBC https://cancerletter.com/drugs-and-targets/20260702_8b/

Despite overall decline in secondary cancer diagnoses, female lung cancer survivors saw 60% increase from the 1970s to the 2010s, VCU Massey analysis finds https://cancerletter.com/clinical-roundup/20260702_7b/

Colorectal cancer is now the deadliest cancer in men and women under 50, surpassing breast cancer and cervical cancer in women, according to the American Cancer Society. (@americancancersoc.bsky.social) https://cancerletter.com/clinical/20260702_1/

RWJBarnabas Health, Rutgers Cancer Institute open Melchiorre Cancer Center in North Jersey (@rutgerscancer.bsky.social) https://cancerletter.com/in-brief/20260626_7d/

CDC updates ACIP charter https://cancerletter.com/cancer-policy/20260702_5b/

NCI Trials for July 2026 https://cancerletter.com/nci-trials/20260702_9/

FDA approved 17 new cancer treatments in 2025, OCE annual report states https://cancerletter.com/drugs-and-targets/20260702_8a/

More than 50 million Americans remain unscreened for colon cancer New guidelines offer another option. Guest editorial by AmirAli Talasaz, PhD. https://cancerletter.com/news-analysis/20260619_4/

Early-onset colorectal cancer is behaving like a new, biologically distinct disease, researchers note One woman’s pregnancy shows how this distinction matters @americancancersoc.bsky.social https://cancerletter.com/clinical/20260702_1/

AACR urges OMB to retract proposed rule on federally funded research https://cancerletter.com/cancer-policy/20260702_5a/

Is it time to re-assess the practice and practicality of screening colonoscopy? Modeling data in ACS guideline support greater use of noninvasive tests to ease system strain, save lives. Guest editorial by Paul J. Limburg, MD, MPH. https://cancerletter.com/trials-and-tribulations/20260702_3/

Robert Mayer tells us about pancreatic cancer’s hopeless past as new data shows promise https://cancerletter.com/in-the-archives/20260626_5/

MammaPrint + BluePrint genomic profiling predicts anthracycline chemotherapy benefit in HR+HER2- early-stage breast cancer https://cancerletter.com/clinical-roundup/20260702_7a/

Maura Gillison, who identified the role of HPV in head and neck cancer, changing the standard of care, dies at 61 @mdanderson.bsky.social https://cancerletter.com/obituary/20260702_2/

The proposed [HHS] program would rely on U.S. academic medical centers or contract research organizations as collaborators to shorten the time between drug identification to first-in-human studies. https://cancerletter.com/regulatory-news/20260626_2/

Researchers at @rutgerscancer.bsky.social and Rutgers Business School build simulation method to reduce cancer treatment times https://cancerletter.com/clinical-roundup/20260626_9d/

Mezigdomide + carfilzomib + dexamethasone regimen reduces disease progression in r/r MM, phase III trial finds https://cancerletter.com/clinical-roundup/20260626_9c/

Kevin Becker named associate chief for MUSC Health Oncology ICCE https://cancerletter.com/in-brief/20260626_7c/

Bradley Cairns, PhD: "Karen helped define a model for what a great institution should be—one that refuses to separate science from humanity, healing from beauty, or discovery from care." @huntsmancancer.bsky.social https://cancerletter.com/obituary/20260626_4/

Sigvotatug vedotin misses OS primary endpoint vs. docetaxel in phase III trial in previously treated metastatic non-squamous NSCLC https://cancerletter.com/clinical-roundup/20260626_9b/

In the June episode of The Directors, two Midwestern cancer center directors, Mark Burkard and Jeffrey Miller, discussed the financial and logistical challenges confronting cancer care outside major metropolitan hubs. https://cancerletter.com/podcastc/20260626_1/

Health ministry in Japan approves Sarclisa for MM https://cancerletter.com/drugs-and-targets/20260626_10d/

"Dr. Fraumeni, to all who worked with him, but 'Skippy' to his family, was a generous and innately inquisitive investigator who had a sixth sense about patterns and connections in cancer epidemiology," writes Stephen J. Chanock. https://cancerletter.com/obituary/20260626_3/

AACR releases 2026 Cancer Disparities Progress Report https://cancerletter.com/clinical-roundup/20260626_9a/

"Some lives leave their mark not only on the people who loved them, but also on the very places where others come to seek hope. Karen Haight Huntsman’s was such a life," writes Bradley Cairns, PhD. @huntsmancancer.bsky.social https://cancerletter.com/obituary/20260626_4/

The Foundation for AIDS Research opens RFP to fund non-HIV cancer research https://cancerletter.com/funding-opportunities/20260626_8a/

@ec.europa.eu approves Maviret for the treatment of acute HCV https://cancerletter.com/drugs-and-targets/20260626_10c/

HHS earlier this week rolled out a cluster of initiatives related to simplifying clinical trials, presenting these measures as a government-wide effort to maintain America’s leadership in early-stage drug development. https://cancerletter.com/regulatory-news/20260626_2/

@ec.europa.eu approves Padcev + Keytruda as perioperative treatment option for cisplatin-ineligible patients with resectable muscle-invasive bladder cancer https://cancerletter.com/drugs-and-targets/20260626_10b/

The better cancer centers become at keeping patients alive, the more expensive cancer care becomes. This brutal tradeoff hits harder in rural areas, where the cancer burden is higher and the investigator and clinical trial representation is lower. https://cancerletter.com/podcastc/20260626_1/

Medical College of Wisconsin Cancer Center receives $27M gift to advance cancer research (@medicalcollegeofwi.bsky.social) https://cancerletter.com/in-brief/20260626_7b/

OMB draft rule politicizing research should be rescinded, House Dems urge in a letter to Bhattacharya https://cancerletter.com/cancer-policy/20260626_6b/