Gokul Rajan
@gokulrajan.bsky.social
đ€ 46
đ„ 49
đ 60
engrams, genes, photons, danionella etc.
https://gokulrajan.xyz/
www.nature.com/articles/s41...
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Clarifying the conceptual dimensions of representation in neuroscience - Nature Reviews Neuroscience
Appeals to representation are widespread, despite neuroscientistsâ uncertainty about what kind of findings count as evidence for such claims. In this Perspective, Pohl and colleagues develop a unified...
https://www.nature.com/articles/s41583-026-01030-8
2 months ago
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reposted by
Gokul Rajan
Benjamin Judkewitz
2 months ago
Tiny, transparent, and now charted! Our brain atlas of adult Danionella cerebrum includes >200 annotated regions, 29 whole-brain in situs, and male/female reference volumes â openly available, versioned and extendable. Work by
@nkadobyansky.bsky.social
and team.
www.biorxiv.org/content/10.6...
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Gokul Rajan
Prakash Lab at Stanford
2 months ago
â.global catastrophe since many incredible programs are not currently being funded. Parasites donât carry passports. Diseases spread across countries, so being able to survey & address these pathogens in one part of the world benefits public health everywhere.â
www.the-scientist.com/a-low-cost-s...
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A Low-Cost, Self-Driving Microscope Could Speed Up Infection Diagnostics
Engineer Manu Prakash helped develop a malaria-finding microscope that works in low-resource settings, improving access to sensitive infectious disease diagnostics.
https://www.the-scientist.com/a-low-cost-self-driving-microscope-could-speed-up-infection-diagnostics-74202
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Gokul Rajan
Alex Schier
2 months ago
Very happy to see this out. đ
@yinanwan.bsky.social
Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science
www.science.org/eprint/5MHTM...
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Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
https://www.science.org/eprint/5MHTMR4RZ75TTPBZSW4J/full?activationRedirect=/doi/full/10.1126/science.adt3439
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Gokul Rajan
10 months ago
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reposted by
Gokul Rajan
Benjamin Judkewitz
3 months ago
First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by
@joerghenninger.bsky.social
,
@mh123.bsky.social
sky.social
and team.
www.biorxiv.org/content/10.6...
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there is a very good case for replacing all paper pushers with LLMs.
3 months ago
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this is news to me. i enjoyed reading Ramachandran as a kid; in fact, i even had my copy of the tell-tale brain autographed by him. it's unfortunate to learn that people i admired, like Pinker and Ramachandran, did not distance themselves from a predator.
theprint.in/feature/vs-r...
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The Indian-American man VS Ramachandran whose study Epstein funded
VS Ramachandran is popularly known in American intellectual circles as a âlatter-day Marco Polo.â He was also in Newsweekâs list of â100 Most Prominent People to Watch in the 21st Century.â
https://theprint.in/feature/vs-ramachandran-epstein-research-funding/2859357/
3 months ago
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doing a postdoc is hard enough financially (and personally for many re:two-body problem). you shouldn't have to fight an immigration system and a sick nested bureaucracy to just do science. while also being flooded w/ endless performative stuff around you. please choose wisely where you work.
3 months ago
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ai can do science. ai can do art. well, at least i'm happy there's no incentive [yet] to use ai and corrupt sciart. brain. |F|=1, phase preserved; inverse fourier transform.
3 months ago
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reposted by
Gokul Rajan
Michael Orger
3 months ago
Very happy to see this paper come out from Lucas Martins
@d-lucas.bsky.social
and Alexandre Laborde. They developed an awesome framework, built with .NET, for developing software to run demanding high-speed behavior and functional imaging experiments.
dx.plos.org/10.1371/jour...
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so, it is 45; and not 42.
www.science.org/doi/10.1126/...
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A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
https://www.science.org/doi/10.1126/science.adt2760
3 months ago
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correlation doesn't mean causation, but does lack of correlation mean lack of causation?
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.02.09.704821v1.full.pdf+html
3 months ago
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there is hope
www.nature.com/articles/s41...
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Trust in scientists and their role in society across 68 countries - Nature Human Behaviour
What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.
https://www.nature.com/articles/s41562-024-02090-5
3 months ago
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phone autocorrected omw to omr. luckily the receiver of the text shares an interest in sensorimotor integration! đ
3 months ago
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put the biology back in computational biology. it's getting ridiculous.
4 months ago
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human-level intelligence benchmarks are a trap. the more humans become dependent on LLM, the lower the threshold becomes to achieve human-level intelligence without any absolute increase in machine intelligence. đ
4 months ago
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reposted by
Gokul Rajan
Filippo Del Bene
4 months ago
Proud to share our new paper uncovering how Lrrn-mediated targeting of retinal ganglion cells assembles circuits for brightness and contrast detection â led by my outstanding PhD student Elena Putti and made possible through wonderful collaborations.
www.science.org/doi/10.1126/...
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LinkedIn
This link will take you to a page thatâs not on LinkedIn
https://lnkd.in/ekYNTKxc
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ZVV's in-app check-in/out toggle is probably one of the best public transport ticketing systems i've ever come across. đšđ
4 months ago
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The second best immersive way to experience the depressing state of science funding in the US.
www.nature.com/immersive/d4...
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US science after a year of Trump: what has been lost and what remains
A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.
https://www.nature.com/immersive/d41586-026-00088-9/index.html
4 months ago
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even if you exclude the 281 consortium authors, there are still 50 other authors in this paper, including 3 co-first authors. how does the responsibility fall on 1? i'd be very interested in understanding the investigation if it exists publicly (it should!!).
add a skeleton here at some point
4 months ago
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Read this recently and I recommend it.
add a skeleton here at some point
4 months ago
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As an alum of Marie Curie Actions COFUND program, I highly recommend this. It is easily one of the best PhD training programs in the world.
add a skeleton here at some point
4 months ago
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every well written piece now gets labelled as "AI generated" by people (and softwares). this is bad for good writers. here is Watson and Crick's seminal paper from 1952 which is apparently "92% AI generated". (tested with tools that claim 99-100% accuracy!)
4 months ago
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never have i used the words "seminal" or "seminar" and thought of "semen of men". lol my 7th grade english teacher taught that "nice" originally meant ~foolish. a good reminder that etymology is great for appreciating evolution of language; but not for dictating contemporary usage.
4 months ago
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only three possibilities here: 1/ you can be the richest man and still not have the intelligence to objectively analyze a video evidence. 2/ you can be one of the most powerful people alive but still be unable to speak your mind, so as to please a few people. 3/ you're just vile.
5 months ago
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so, two authoritarian regimes (venezuela and china) were doing a peaceful, diplomatic energy trade when a "democracy" (usa) attacked them, kidnapped the leader and declared "to run" the country and oil reserves. and most of the western hemisphere sees nothing wrong with this.
5 months ago
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Many biological comparisons implicitly test one null: are labels exchangeable? Minimal label-flip/ sign-flip permutation tests for arbitrary user-defined statistics, with conservative, assumption-light inference.
github.com/BioCommons-L...
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GitHub - BioCommons-Lab/labelFlip-and-signFlip: Two-sample permutation tests in MATLAB for independent sample and paired sample designs, with support for arbitrary user-defined test statistics.
Two-sample permutation tests in MATLAB for independent sample and paired sample designs, with support for arbitrary user-defined test statistics. - BioCommons-Lab/labelFlip-and-signFlip
https://github.com/BioCommons-Lab/labelFlip-and-signFlip
5 months ago
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you're can't do any real science if you are not comfortable with feeling stupid. if you are doing science (at any level), you should absolutely read this ~17 years old piece -- the importance of "absolute stupidity" in science.
journals.biologists.com/jcs/article/...
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The importance of stupidity in scientific research
I recently saw an old friend for the first time in many years. We had been Ph.D. students at the same time, both studying science, although in different areas. She later dropped out of graduate school...
https://journals.biologists.com/jcs/article/121/11/1771/30038/The-importance-of-stupidity-in-scientific-research
9 months ago
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Der Weg zur Höllen sey mit lauter gutem Vorsatz gepflastert.
9 months ago
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imho: skills are overrated; motivation is underrated. 1) with motivation, new skills come fast. 2) without it, skills mean nothing.
9 months ago
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two very different hunters i'm playing with: drosera and hippocampus.
9 months ago
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Peer-review and peer-fund pilot projects on
@researchhubf.bsky.social
! I just funded: NeuroSC: Leveraging Pretrained Single-Cell Models for Brain Cell Classification on ResearchHub.
www.researchhub.com/fund/4262/ne...
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NeuroSC: Leveraging Pretrained Single-Cell Models for Bra...
NeuroSC: Leveraging Pretrained Single-Cell Models for Brain Ce...
https://www.researchhub.com/fund/4262/neurosc-leveraging-pretrained-single-cell-models-for-brain-cell-classification?utm_source=x&utm_medium=social_share
10 months ago
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New leaves, new tentacles, more hunting. đ±
add a skeleton here at some point
10 months ago
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Turns out that I had some research tokens on
@researchhubf.bsky.social
-- earned from my past publications(!!) -- that I could use to fund new research proposals submitted by others. I just did exactly that. Why have you not? Be the change you want to see.
www.researchhub.com/fund/4261/ef...
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Effects of psilocybin and related compounds on neuroprote...
Effects of psilocybin and related compounds on neuroprotection...
https://www.researchhub.com/fund/4261/effects-of-psilocybin-and-related-compounds-on-neuroprotection-in-human-stroke?utm_source=bluesky&utm_medium=social_share
10 months ago
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TIL: when I see the electric scooters in the sea or streams, it's not the app glitching!
10 months ago
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Not kidding -- just read a paper where the person who made the discovery was thanked in the acknowledgements. How do I know? Because he was literally thanked as The discoverer! Welcome to science, where credit goes to the cool dude with the mic.
10 months ago
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10 months ago
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When a paper cites everything around the key prior work but specifically skips the actual prior work that directly addressed their claim, it tells me more about the authors than the topic.
10 months ago
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when you select for "sexiness" and overlook rigor, science becomes clickbait. this arsenic life paper wasnât just a one-off fluke -- it is a symptom of what happens when journals and funders chase headlines.
www.science.org/content/arti...
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Fifteen years later, Science retracts âarsenic lifeâ paper despite study authorsâ protests
Belated decision on widely disputed 2010 study pleases some critics but puzzles and dismays others
https://www.science.org/content/article/fifteen-years-later-science-retracts-arsenic-life-paper-despite-study-authors
10 months ago
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Just found out that my first-ever trainee -- a bachelorâs student from Sorbonne during my PhD -- is now doing a PhD in Neuroscience. Not taking any credit, but it still feels really good. :)
10 months ago
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Bold questions. Thoughtful reasoning. Smart tools. That's what it celebrates!
add a skeleton here at some point
10 months ago
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Ever wonder if individuals can make a difference -- or if we must wait for institutions to catch up? Sometimes, itâs worth trying the former. The Danionella Prize: a tiny, personal gesture to reward curiosity, from India and Myanmar.
danionellaprize.xyz
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The Danionella Prize
https://danionellaprize.xyz/
10 months ago
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A beautiful carnivore just entered our plant collection! đ±
11 months ago
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Most people donât lack values -- they just lack the courage to live them when itâs inconvenient to them. Integrity isnât measured by what you say you care about -- itâs what you do when no one else speaks up.
11 months ago
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what?!
www.nature.com/articles/s41...
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A biocompatible Lossen rearrangement in Escherichia coli - Nature Chemistry
Biocompatible chemistry merges chemo-catalytic reactions with cellular metabolism for sustainable small-molecule synthesis. Now a biocompatible Lossen rearrangement has been demonstrated to control ba...
https://www.nature.com/articles/s41557-025-01845-5
11 months ago
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why is this called gold open access? is it because it is fixed at the price of 146.6 gm of gold?
11 months ago
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Good ideas can cross continents in seconds but take years to cross an office desk.
11 months ago
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In my weekly scan-every-journal marathon, last week I enjoyed reading this paper. Insightful work on 50,000 years of Indiaâs genetic history and caste endogamy. I suspect colonial disruptions further amplified these disease burdens.
www.cell.com/cell/fulltex...
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50,000 years of evolutionary history of India: Impact on health and disease variation
A genomic study of 2,762 individuals from India offers important insights into the genomic diversity and evolutionary history of the subcontinent and highlights the extensive genetic variation, gene f...
https://www.cell.com/cell/fulltext/S0092-8674(25)00462-3
11 months ago
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"America has done what no other country on earth could do." Indeed, and for many decades now. Interfering in international geopolitics that is none of their business.
11 months ago
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