📣 Call for Papers – Systematic Reviews & Meta-Analysis Critical Care Science welcomes submissions of Systematic Reviews & Meta-Analyses addressing key topics in #ICU #PedsICU 💎 Open Access:free to read, share & publish!  No APCs.No submission fees. 👉 Submit your manuscript criticalcarescience.org

🧠 Is it time for SOFA 2.0 in #ICU ? ➡️ #SOFA score brought standardization to organ dysfunction assessment; ➡️ Advances in tech, sedation,new therapies demand an update; ➡️ SOFA 2.0 brings global input, data-driven validation, methodological rigor. criticalcarescience.org/article/the-...

Do we underestimate right ventricle & venous system in #ICU? ➡️ RV function & VR: essential for🫀output & tissue perfusion ➡️ Guyton’s model & concept of mean systemic filling Press : insights into fluid & vasopressor management 🎯 Great narrative #Review criticalcarescience.org/wp-content/u...

👶🏼 How can we identify #palliativecare needs in newborns admitted to #NICU? 🇧🇷 study w/188 neonates in a ⬆️risk Brazilian maternity ➡️ Palineo Score developed using 7 clinical domains ➡️ Exceptional accuracy to guide early & appropriate #palliativecare criticalcarescience.org/article-keyw...

👨‍👩‍👧‍👦 Can liberalized family presence in the ICU improve care & how do we make it work? ➡️ Structured implementation involves planning, staff training, & family education. 🎯 Evidence shows benefits for patients, families, & care quality. criticalcarescience.org/wp-content/u... #ICU #PedsICU

🤖 How can AI improve #ICU & what are the risks? ➡️ AI tools support diagnosis, prediction & resource allocation ➡️ concerns remain:bias, transparency, inequity & environmental impact 🎯 Mitigating bias is 🗝️to equitable implementation in ICUs. criticalcarescience.org/wp-content/u...

🌏 Can Brazil and ANZ build a new model of global collaboration in ICU ? ➡️ cross-continental alliances are no longer optional — they're essential ➡️ Brazil & ANZ bring complementary strengths: large populations, diverse ICU case-mix, & aligned values www.sciencedirect.com/science/arti...

‼️Call for Papers – Critical Care Science
🔎 Focus: Original Research from low- and middle-income countries
📎Deadline: November 1, 2025 #ICU #PedsICU #FoaMed #FoaCc #CCS #LMIC #sepsis #Some4MV Submit your paper at: criticalcarescience.org

🧠 organ dysfunction has been incorporated into the core definition of pediatric #sepsis ❗️Pediatric delirium (PD) is a clear manifestation of CNS dysfunction, but PSS focuses only on GCS/pupils & omits delirium Viewpoint 📝: criticalcarescience.org/wp-content/u... #PedsICU #pediatricDelirium #CCS

🧒🏼 How is ped #palliative extubation in 🇧🇷 #PedsICU ? ➡️ Case series w/ 27 children (5 d–10 y) in a tertiary PICU ➡️ Main indications: neurological impairment & IMV weaning failure ➡️ Family presence & shared decision-making were part of most cases criticalcarescience.org/article/prac...

Important work from distinguished brazilian intensivists Daniela Souza, José Colleti e Andrea Ventura

🦠 Do 🇧🇷pediatricians recognize #sepsis & septic shock accurately? 🇧🇷 355 physicians 🔹 Most participants relied on SIRS-based criteria, intuition & clinical signs for diagnosis 🔹 Only 31.3% & 30% correctly identified sepsis & severe sepsis #PedsICU #FoaMcc criticalcarescience.org/article/unco...

🔎 Have we truly advanced in #GenderEquity in critical care medicine? ➡️ Women remain underrepresented in leadership, authorship,grant awards ➡️ Initiatives exist,but structural barriers & workplace culture continue to limit progress criticalcarescience.org/article/gend... #ICU #PedsICU #WomenInICU

🫁 Can 1 hour of positive pressure ventilation post SBT reduce extubation failure? 🔹Multicenter feasibility #RCT in 🇧🇷 w/65 #ICU pts 🔹 Pts ventilated >72h were randomized after successful SBT; 🔹 Extub failure in 7 d: 28.1% (intervention) vs. 42.4% (control) criticalcarescience.org/wp-content/u...

💧 Should fluid therapy in #ICU pts be shorter & more strategic? 🔹 Excessive fluid resuscitation=worse outcomes; 🔹#ROSE model & deresuscitation strategies aim to balance perfusion+ 💧 overload; 🔹Tools like US & bioimpedance can guide safe fluid removal criticalcarescience.org/article/flui...

🤖 Can artificial intelligence improve prediction of postoperative complications #ICU patients? 🔹 #AI models integrate perioperative data to identify at-risk patients 🔹 Applications include AKI, sepsis, mortality, ICU admission &more. criticalcarescience.org/article/arti... #ICU #PedsICU

🏥 Can general intermediate care units (IMCUs) improve #ICU efficiency & patient safety? 🔹 IMCUs fill the gap between wards & ICUs 🔹 Reduce readmissions & optimize patient allocation 🔹 Improve comfort, allow family presence & enhance monitoring. criticalcarescience.org/article/gene... #CCS

🧠 Bayesian analysis in #clinicaltrials: how does it differ from the traditional approach? ❗️Bayesian analysis is being used w/ increasing frequency in #ICU research & brings advantages/disadvantages compared to traditional Frequentist techniques #Review criticalcarescience.org/article/unde...

🕯️ The legacy of Prof. Rinaldo Bellomo for critical care & scientific publishing ➡️Special Editorial ➡️ A pioneer, mentor, & visionary in #ICU medicine ➡️ His legacy continues to inspire a more inclusive, ambitious &collaborative ICU community criticalcarescience.org/wp-content/u...

#BRICnet: shaping the landscape of #ICU research in 🇧🇷 & beyond. 🔹Founded in 2007, has become a leading clinical research network in ICU; ➡️ 71 publications ➡️ 15 RCTs & 14 obs.studies ➡️ Strategic partnerships w/ international networks like ANZICS, CCCTG, ESICM criticalcarescience.org/article/braz...

🦠 Improving sepsis outcomes in 🇧🇷 Strategies & initiatives ➡️ @ILASepse has led initiatives focused on awareness, education & quality of care ✅ In this viewpoint, authors discuss recent strategies & initiatives aimed at ⬇️ burden of #sepsis criticalcarescience.org/article/impr... #ICU #PedsiCU

📺 CPR in 🇧🇷 medical television shows: a descriptive &quality assessment study ➡️Analysis of 59 CPR scenes from 3 🇧🇷 medical TV shows ➡️ Major deviations from ACLS guidelines were common: delayed CPR, incorrect defibrillation, poor airway management. #ICU #PedsICU criticalcarescience.org/article/card...

🏠 Home care after #ICU discharge:a global perspective on challenges & opportunities ⬆️readmission rates & long-term disabilities after ICU discharge; 🔹Home visits & follow-up calls ⬇️ readmissions & improve outcomes #FoaMed #FoaMcc #PedsICU #CriticalCareScience criticalcarescience.org/article/home...

Im proud & honored to be part of editorial board of @critcarescience.bsky.social, full open access journal -no fee for authors & readers. As science should be! CCS is the official journal of associação de medicina intensiva brasileira & Sociedade Portuguesa de cuidados intensivos. #ICU #PedsICU

🔵Message from our Editor-in-chief 🔹Advancing for Growth, Quality, & Global Visibility in 2025 We are proud to announce key updates that mark a new phase for CCS: ➡️ New visual identity ➡️ Expanded Editorial Board: more diverse,international experts ➡️ Updated Author Guidelines criticalcarescience.org

📚 Translation, cross-cultural adaptation & clinimetric evaluation of the Chelsea Critical Care Physical Assessment (CPAx) for Brazilian Portuguese: 🔹 ⬆️content validity index (CVI 0.91); 🔹 Excellent interrater reliability (ICC 0.997) #FoaMed #ICU #FoaMcc criticalcarescience.org/article/braz...

💉 Are sedation practices different for patients intubated in the #ED compared to the #ICU? ➡️ Retrospective cohort study comparing sedation practices between ED & ICU pts 🔹 264 pts included (95 ED vs. 169 ICU); See the results at: criticalcarescience.org/article/seda... #ICU #PedsICU #FoaMed #FoaMCc

🫁🫀 Pulmonary artery pressure assessed by catheterization & its concordance/transthoracic echocardiographic estimates: 🇨🇴 Data from multicenter cohort of patients with pulmonary hypertension in Colombia; ➡️ Retrospective study ➡️ 633 pts #ICU #FoaMed #FoaCCM criticalcarescience.org/article/pulm...

🫁 Can early weaning from invasive mechanical ventilation using high-flow nasal oxygen (#HFNO) improve outcomes in patients w/acute hypoxemic resp failure? 🇮🇳 Indian #RCT, 80 patients ➡️ Extubation to HFNO vs. Extubation to Venturi Mask criticalcarescience.org/article/earl... #ICU #PedsICU #Some4MV

Publication from our editor-in-chief, Dr. Jorge Salluh, on the neighboring network #Linkedin, explaining why publish in #CriticalCareScience! #ICU #PedsICU #MedEd #FOAMed #NoFeeForPublication

🔬Just published! ➡️ In this viewpoint,authors discuss pitfalls researchers should be aware of when conducting #ICU #research 🔹Lack of relevant research question 🔹Definition of inclusion & exclusion criteria 🔹New methods are not always the best! & more! criticalcarescience.org/article/comm...

💉 Dexmedetomiditine 🆚 Agitation in #ICU ⚠️ The largest assessment of impact of #DEX on agitation in #ICU pts 🇦🇺 Austin ICUs, Melbourne 🏥 2052 pts-June 2016 &April 2021 ✅ Novel techniques - Target trial emulation comparing effects of early Dex on outcomes of pts criticalcarescience.org/article/a-ta...

🦠Antimicrobial resistance of S.pneumoniae from invasive pneumococcal disease in 🇧🇷: 🩸 411 isolates of S. pneumoniae from blood cultures; 🏥 16 tertiary hospitals; ✅ Approximately 1 in 7 S. pneumoniae isolates were nonsusceptible to ceftriaxone (for meningitis) criticalcarescience.org/article/anti...

🫁 Application of New #ARDS Guidelines at the bedside: 🔹2023:ESICM 🔹2024:ATS along w/#ARDS new global definition ✅ In this viewpoint, authors discuss several evidence-based recommendations from the new guidelines for optimizing patient diagnosis & treatment criticalcarescience.org/article/appl...

⚠️ Autonomy & Vulnerability in #ICU Patients:Challenging Landscape for the Intensivist 🔄 Respect for autonomy & human vulnerability are bioethical principles that often create decision-making dilemmas in #ICU ✅ practical approach to overcoming these challenges👇🏻 criticalcarescience.org/article/prac...

🩺 How to Manage Chronic Dialysis Patient in #ICU? 📈 global hemodialysis population has ⬆️by 50% in past decade #NarrativeReview ➡️ Indications ➡️ Volume status assessment ➡️ Fluid resuscitation ➡️ Intradialytic emergencies ➡️ Infections criticalcarescience.org/article-keyw... #CriticalCareScience

Critical Care Science is a journal that believes in global inclusion and equality. In recent years,the number of women on the editorial board has increased by 30% and we are moving towards a well-balanced gender ratio. Happy Women's Day to all women!! #CriticalCareScience #WomensDay #ICU #PedsICU

📄 Best practices 4 guideline development in #ICU ➡️ Rigorous systematic reviews w/ clear criteria, comprehensive searches, bias assessment & meta-analysis; ➡️ Use #GRADE framework to appraise evidence certainty & the strength of recommendations; & more! criticalcarescience.org/article/best...

📊 ICU Scoring Systems: A Practical Guide for the Intensivist ➡️ ICU prognostic scores are not disease-specific. How should they be used? ⚠️ 8 Pitfalls in ICU prognostic score use (and how to overcome them)❗️ criticalcarescience.org/article/how-... #CriticalCareScience #ICU #PedsICU #FoaMed #FoaMCC

🫁 Will SpO2/FiO2 Replace PaO2/FiO2? 🩺 PaO2/FiO2: gold standard 4 diagnosing acute hypoxemic resp failure, though ABG analysis isn’t always feasible,especially in low-resource settings 💡 SpO2/FiO2: noninvasive alternative for diagnosis,monitoring & prognosis criticalcarescience.org/article/peri...

🏥 10 Key Strategies for Early Mobilization in #ICU 💪 Technological advances & teamwork improve survival but bring challenges like ICU-acquired weakness,where timely physical therapy is crucial 🔑 recommendations 4 effective rehabilitation of patients criticalcarescience.org/article/prot... #FoaCC

🫁 New on #MechanicalVentilation 🚨 joint effort by 2 Brazilian Medical Societies #ICU #Pneumology 📋38 evidence-based topics on #MV 📖 Practical guidance to improve 🛏️care Collab of 75 experts from across 🇧🇷 ✔️ Scoping reviews of 20 y of ⬆️impact public #SoMe4MV criticalcarescience.org/article/join...

The Critical Care Science Journal ends 2024 w/a very positive balance! ✅Submission to JCR & Embase, 2 major indexing platforms ✅40% increase in submissions, w/ > proportion from international researchers ✅⬆️quality submissions Read the full editors' message criticalcarescience.org #ICU #PedsICU

📜Viewpoint article:clinical guide to assess immune response to #sepsis: from bench➡️bedside ‼️biological duality: combination of inflammatory & anti-inflammatory signaling pathways,w/ immunoparalysis assoc w/ higher mortality & hospital infections #ICU #PedsICU criticalcarescience.org/article/a-cl...

Differences in relative importance of predictors of short-&-long-term mortality among #ICU patients w/cancer 🇧🇷 Retrospective cohort; ➡️ predictors of mortality post ICU admission in pts w/cancer who experienced unplanned ICU admission. #FoaMed #CCS #CriticalCareScience @criticalcarereviews.com

🏥 Family visitation restrictions vs. psychological distress among critical care clinicians: 🇧🇷 National Survey conducted during most severe peak of #Covid19 ➡️ Healthcare worker distress was assessed (burnout, depression,anxiety,irritability suicidal thoughts) criticalcarescience.org/article/perc...

💉 Sedative Choices in #ICU 🧠 A great update on current landscape of sedation management in ICU: ➡️ New scenario& old tools ➡️ Concerning sedative choice ➡️ Monitoring sedation level ➡️ Inhaled sedation ➡️ Future directions criticalcarescience.org/article/enha... #ICU #PedsICU #FoaMed #CCS

Assessing autonomic dysfunction in #sepsis 🇧🇷 Observational study; ➡️ 152 patients; 💉 Semiorthostatic stress test (head elevation - 0 to 60 degrees); ➡️ Perfusion index values, hemodynamics, and cardiac ultrasound data were evaluated. criticalcarescience.org/article/peri... #ICU #PedsICU #FoaMed

🔬Is #ICU research activity associated w/better organization & care delivery? ➡️ Secondary analysis of #ORCHESTRA study; 🇧🇷 93 ICUs; ➡️ Scientific productivity & research activities were assessed, using indicators of care for comparison criticalcarescience.org/article/scie... #FoaMed #FoaMcc #Medky

🔎 Central Venous Press #CVP vs. Fluid Therapy💧 🇧🇷 Prospective observat study; ➡️ #ICU patients under MV adequately sedated; ➡️ 💧expansion (💧bolus or 💧 challenge) w/crystalloids; #CVP was obtained at baseline, 5’, 10’ & 15’ post💧infusion #PedsICU #ICU #FoaMed criticalcarescience.org/article/change…