Daniel Zabransky
@danielzabransky.bsky.social
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Assistant professor of oncology at Johns Hopkins. Physician-scientist studying GI cancers.
reposted by
Daniel Zabransky
Nature Portfolio
7 months ago
A study in Nature Communications reports dynamics of age-related divergence of circulating immune responses in patients with solid tumors treated with immune checkpoint inhibitors.
go.nature.com/3GlO49I
#immunosky
#medsky
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reposted by
Daniel Zabransky
Mark Yarchoan
7 months ago
New study led by
@danielzabransky.bsky.social
lab Older adults respond well to anti-PD1 therapy, despite age-related immune changes ๐
nature.com/articles/s41...
Findings unlikely to extend to other forms of immunotherapy (eg cancer vaccines, etc.) which rely on naive T cells
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Age-related divergence of circulating immune responses in patients with solid tumors treated with immune checkpoint inhibitors - Nature Communications
The aging immune system is characterized by changes in immune cell frequencies and functionality. Here the authors report dynamics of age-related divergence of circulating immune responses in patients...
https://nature.com/articles/s41467-025-58512-z
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