Bernhard Magerl (@bernhard-m.bsky.social)

Maternal ELL3 loss-of-function leads to oocyte aneuploidy and early miscarriage - Nature Structural & Molecular Biology The authors show that ELL3 maintains chromosomal ploidy by promoting spindle assembly and driving chromosome movement in oocytes. Deficiency of ELL3 results in oocyte aneuploidy and may lead to early ... https://nature.com/articles/s41594-024-01471-8