@thomthum.bsky.social
π€ 140
π₯ 54
π 7
Proud of Kaisa Pakari
@kpakari.bsky.social
to receive the 2025 Schmeil young researcher award for her
#PhD
thesis. She established π models to address disorders of
#glycosylation
#CDG
by advancing
#baseediting
range for precise genome editing
@wittbrodtlab.bsky.social
@cos.uni-heidelberg.de
3 months ago
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reposted by
Gesellschaft fΓΌr Entwicklungsbiologie e.V.
4 months ago
Are you in Germany in September (25th-27th) and ready to present your science? no further hesitation and register for the 15th GfE School on "Lineages: Revealing how Cells make Embryos and Tissues" at Schloss Reisensburg:
www.vbio.de/gfe-entwickl...
all
#devbio
enthusiasts and interested welcome!
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reposted by
Medaka PI Meeting
5 months ago
LAST CHANCE TO REGISTER! Calling all medaka researchers and enthusiasts! Don't miss your chance to connect with the growing medaka community, share ideas, and spark new collaborations! The Medaka PI/ERC Indigene Meeting 2025 is just around the corner! REGISTER NOW β
meetmedaka.com
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new
#preprint
: mRNA delivered degron system w/ GFP-nanobody to efficiently reduce GFP-tagged proteins in an inducible manner in π Case study: reduction of PMM2 (basis for ER-based
#glycosylation
) causes hypoglycosylation reported from CDG-patients
www.biorxiv.org/content/10.1...
#CRISPR
#RareDisease
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Establishing an auxin-inducible GFP nanobody-based acute protein knockdown system to mimic hypomorphic mutations during early medaka embryogenesis
Creating hypomorphic mutations are crucial to study gene function in vivo, especially when null mutations result in (embryonic) lethality. This is especially the case for enzymes involved in glycosyla...
https://www.biorxiv.org/content/10.1101/2025.05.23.655727v1
5 months ago
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reposted by
Lucie Zilova
6 months ago
Happy to share our new preprint on lens morphogenesis in ocular organoids. All thanks to Elin Stahl, Miguel Angel Delgado-Toscano, Ishwariya Saravanan, Anastasija Paneva and Jochen Wittbrodt
@wittbrodtlab.bsky.social
www.biorxiv.org/content/10.1...
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reposted by
Ewan Birney
5 months ago
New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz +
@saulpierotti.bsky.social
from
@wittbrodtlab.bsky.social
, Felix Loosli, Kiyoshi Naruse and my own lab
www.biorxiv.org/content/10.1...
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Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model
Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...
https://www.biorxiv.org/content/10.1101/2025.04.24.650462v1
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Register quickly and swim by!
#medaka
#meeting
#conference
add a skeleton here at some point
6 months ago
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