🚨 Our parent-of-origin study is out in Nature! 🧬 Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss. 🔗 www.nature.com/articles/s41... Highlights below!

📢 (on more!) New study from our team in the Journal of Translational Medicine: Polygenic and pharmacogenomic contributions to medication dosing: a real-world longitudinal biobank study 🔗 tinyurl.com/25u3a5j7 (thread below) 👇

🎉(1/4) Excited to share that our latest paper is now published! We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @estbiobank.bsky.social , leveraging data from questionnaires and clinical notes using NLP. www.nature.com/articles/s41...

A study in Nature Medicine provides a cross-trait atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses. https://go.nature.com/3G6slSR 🔒

Excited to share our recently published overview of the @estbiobank.bsky.social 🧬 We highlight the unique features of the biobank and the conducted scientific research it has enabled, including the many recall studies that have been carried out over the years! www.nature.com/articles/s41...

💡Can we use real world drug purchase data to study the genetics of medication dosing? We explored this by analyzing 20 years of digital drug dispensing data linked to the @ESTbiobank which hosts 212,000 genotyped participants. 🧵 📄 doi.org/10.1101/2025...

Our popular SPE-course is coming again! Boost your epidemiology & stats skills in R! Join "Statistical Practice in Epidemiology using R" at the University of Tartu, Estonia, June 2–6, 2025. More info: bendixcarstensen.com/SPE/

Happy to share our recent article on metabolomics and incident hypertension in the Estonian Biobank. @kristafi.bsky.social @estbiobank.bsky.social @urmovosa.bsky.social rdcu.be/edbUZ

📢 Excited to share our study in @natmedicine.bsky.social 👉 www.nature.com/articles/s41... We mapped & characterized genetic risk factors for 42 female reproductive health diagnoses. What we found & why it matters? 👇🧵

📣 New blog post on our recent paper on #ADHD genetic liability and health outcomes in people without diagnosed ADHD! @timespan-h2020.bsky.social @estbiobank.bsky.social

It's been a busy December, so I'm only just getting around to sharing our publication on metabolomic and genomic prediction of common diseases in 3 national biobanks. A few highlights in the 🧵! www.nature.com/articles/s41...

🌟 Exciting news: The Leena Peltonen School of Human Genetics returns in 2025! This prestigious summer school brings together leaders in human genetics with PhD students 📅 July 27-31, 2025 📍 Wellcome Genome Campus, UK 📝 Apply by March 7 at www.lpshg.com

🦠 Excited to share our new collection of human gut #archaea species! 🎉 🇪🇪From @ESTbiobank, we present a dataset of 144 strains across 21 species, including 9 entirely new species! A thread 🧵 #MAG #EstMB #TartuMicrobiome #microbiome #humangut

This is what happens when you return research results to biobank participants: ✅ The 2nd most googled “How to…?” question in Estonia 2024: “How to become a biobank participant?” ✅ "Estonian Biobank" among Top 10 search terms. Huge thanks to the entire UniTartu & EstBB teams! ✨

🚨 Our preprint on parent-of-origin effects (POEs) is out! With our novel method, we inferred the parental origin of alleles for >220,000 individuals, uncovering novel insights into genetics, evolution, and health. 👉 Read here: www.medrxiv.org/content/10.1... 👇 Highlights below!

New preprint out on genetic susceptibility to infection with Omicron variants of SARS-CoV-2. International GWAS meta-analysis discovers loci not found for earlier variants of the virus and indicates central role of glycosylation. 👇 www.medrxiv.org/content/10.1...