❗BrainVTA offer PFFs for rapid and reliable modeling of protein aggregation in PD and AD. Products: 1、Tau PFFs (2N4R, P301S, P301L, K18, K18-P301L) 2、SNCA PFFs (mouse, human, E46K, A53T) 3、≥90% purity, TEM-validated. 👇Interested? Let us know and we'll send more details.

❗News︱Advanced Science 👏Prof. Taian Liu’s Team develops an AAV vector toolkit for precise intervention in the direct pathway affected by Parkinson's disease. 👇MORE advanced.onlinelibrary.wiley.com/doi/10.1002/...

❗News︱Theranostics 👏A Novel Strategy for Pain Management! Prof. Lei Chu’s Team developed an ultrasound-responsive piezoelectric hydrogel that effectively ameliorates the pathology of neuropathic pain following nerve injury. 👇MORE www.thno.org/v16p7780.htm

❗News︱Nature Neuroscience 👏Mitochondrial Stress Causes Microglia—the Brain’s “Scavengers”—to Undergo Premature Aging. 👇MORE www.nature.com/articles/s41...

❗Honored to be cited in Autophagy 👏Prof. Peihua Luo’s Team reveals a novel mechanism of alectinib-induced multi-organ toxicity: liver-skin crosstalk mediated by BTD-selective autophagy in the liver. Brain_VTA offers AAV and Ad packaging services. www.tandfonline.com/doi/full/10....

❗Honored to be cited in CCS 👏Prof. Liqun Jiao’s Team reveals a novel mechanism by which oxytocin neurons in the hypothalamic paraventricular nucleus regulate microglia and neutrophils to mediate neuroinflammation. Brain_VTA offers AAV packaging services. link.springer.com/article/10.1...

We’re thrilled to announce that BrainVTA will be exhibiting at #FENS2026! 🎉 📍 Come find us at Booth #30 🗓️ Let’s connect, chat about the latest in neuroscience. And yes — we’ve got some awesome goodies waiting for you. 🎁✨ Don’t miss out — swing by, say hi, and grab your free gift while supplies last!

❗Honored to be cited in Biological Psychiatry 👏Prof. Yan Li’ team reveals a novel gut-brain axis mechanism linking sleep deprivation to anxiety. Brain_VTA offers AAV and HSV packaging services. www.biologicalpsychiatryjournal.com/article/S000...

❗News︱Glia 👏Prof. Shengwei Gan’s Team reveals a novel mechanism by which teprenone regulates the intracellular trafficking of AQP4 in retinal ischemia-reperfusion injury. 👇MORE onlinelibrary.wiley.com/doi/10.1002/...

❗Honored to be cited in Nature Communications 👏Prof. Song Lin’ team reveals that a synergistic imbalance in the dorsomedial prefrontal cortex → lateral habenula “excitation-inhibition” dual pathways drives depression susceptibility. Brain_VTA offers AAV services. www.nature.com/articles/s41...

❗News︱Molecular Psychiatry 👏Prof. Lan Xiao’s Team reveals that inhibiting myelin formation induced by the retrieval of recurrent fear memories can effectively alleviate PTSD-like behaviors. 👇MORE www.nature.com/articles/s41...

❗Honored to be cited in Journal of Neuroinflammation 👏Prof. Jiafeng Wang’ team reveals the mechanism by which the brain-lung circuit drives the sympathetic nerve-neutrophil axis to promote lung injury. Brain_VTA offers PRV packaging services. link.springer.com/article/10.1...

❗News︱Cell Metabolism 👏Prof. Xiangdong Gao’s Team develops an oral GLP-1R agonist for the treatment of Alzheimer's disease. 👇MORE www.sciencedirect.com/science/arti...

❗News︱Cell Reports 👏New Epigenetic Mechanism in Huntington's Disease! Prof. Li Lin’s Team Reveal the Pathogenic Axis Involving mHTT, Transcription Factor TBP, and DNA Demethylase TET1 Uses Pig Model. 👇MORE www.cell.com/cell-reports...

❗News︱Autophagy 👏A Novel Smart Fluorescent Probe! Prof. Xin Li’s Team Develop a "Real-Time Monitor" for Autophagic Flux In Vivo. 👇MORE www.tandfonline.com/doi/full/10....

❗News︱Nature Neuroscience 👏Prof. Zhe Zhang’s Team reveals a novel mechanism by which tryptamine participates in the representation of sleep pressure signals and the regulation of sleep homeostasis. 👇MORE www.nature.com/articles/s41...

❗News︱Exploration 👏Prof. Ru Zhang’s Team reports a novel mechanism driving microglial abnormalities and the pathological progression of Alzheimer's disease. 👇MORE onlinelibrary.wiley.com/doi/10.1002/...

❗Honored to be cited in Communications Biology 👏Prof. Li Zhang’ team discovers a new mechanism by which exercise alleviates anxiety through the modulation of cortical inhibitory neurons. Brain_VTA offers AAV packaging services. www.nature.com/articles/s42...

❗News︱Advanced Science 👏Prof. Rongcan Luo’s Team reveals the molecular mechanism by which microplastics promote the onset and progression of Alzheimer's disease via the gut microbiota-taurine axis. 👇MORE advanced.onlinelibrary.wiley.com/doi/10.1002/...

Excited to share our first red ACh sensor! 🔴 We developed GRAB_rACh1h, the first genetically encoded red fluorescent sensor for recording acetylcholine dynamics in vivo. (1/3)

❗News︱Nature Microbiology 👏Prof. Cen Xie’s Team reveals the key mechanism by which dietary fat drives intestinal lipid absorption. 👇MORE www.nature.com/articles/s41...

❗News︱Cell Death Discovery 👇New Therapeutic Target! Prof. Hao Yu’s Team reveals a novel mechanism by which the E3 ubiquitin ligase FBXW7α regulates amyloid pathology through the modulation of BACE1 ubiquitination and degradation. 👏MORE www.nature.com/articles/s41...

❗News︱Cell Host & Microbe 👏Novel Gut-Brain Mechanism! Prof. Honghong Yao’s Team Reveals for the First Time That Liraglutide Exerts Antidepressant Effects via a Gut Microbiota-Dependent Pathway. 👇MORE www.sciencedirect.com/science/arti...

❗News︱Neuron 👏Prof. Zhaozhu Qiu’s Team reveals that the KAT7-CMPK2 epigenetic pathway drives mitochondrial immune activation in microglia in Alzheimer's disease. 👇MORE www.cell.com/neuron/fullt...

❗News︱Neuron 👏Prof. Cheng Li’s Team maps the single-cell proteomic landscape of aging microglia in mice. 👇MORE www.cell.com/neuron/abstr...

❗Honored to be cited in Science Advances 👏Prof. Lei Xiao’ team reveals the neural mechanisms by which oxytocin signaling in the prelimbic cortex inhibits conditioned fear acquisition. Brain_VTA offers AAV packaging services. www.science.org/doi/10.1126/...

❗News︱Neuron 👏Prof. Ming Lu’s Team reveals the critical role of brain-body neuro-immune communication in stress-induced behavioral abnormalities. 👇MORE www.cell.com/neuron/abstr...

❗Honored to be cited in Advanced Science 👇Prof. Jiangping Liu’ team reveals that astrocytic phenotypic switching in the posterior piriform cortex drives bone cancer pain-depression comorbidity. Brain_VTA offers AAV packaging services. advanced.onlinelibrary.wiley.com/doi/10.1002/...

❗Honored to be cited in JASN 👏Prof. Bicheng Liu’ team reveals that dysregulated 27-HC metabolism enhances the sensitivity of proximal tubular epithelial cells to ferroptosis in ischemic acute kidney injury (AKI). Brain_VTA offers AAV packaging services. www.ovid.com/jnls/jasn/ab...

❗News︱Neuron 👏Prof. Yuqiu Zhang’s Team reports a novel circuit mechanism underlying the comorbidity of chronic pain and depression. 👇MORE www.cell.com/neuron/abstr...

❗News︱Cell Communication and Signaling 👏A novel neuro-immune paradigm! Prof. Xiaowei Huang’s Team reveals that the neuronal tetraspanin TSP-6 suppresses intestinal innate immunity in C. elegans by regulating the release of dense-core vesicles. 👇MORE link.springer.com/article/10.1...

❗News︱Molecular Psychiatry 👏Prof. Rong Jiang’s Team reveals a novel mechanism by which NgR regulates depression-like behaviors via the dorsal hippocampal CA3 → ventral tegmental area → nucleus accumbens neural circuit. 👇MORE www.nature.com/articles/s41...

❗News︱Neuron 👏New Evidence on Itch! Prof. Bo Duan’s Team Reports That Specialized Hair-Innervating Afferents Are the Exclusive Pathway for Mechanical Itch Transmission. 👇MORE www.cell.com/neuron/abstr...

❗Honored to be cited in Cell Discovery 👏Prof. Jiangning Zhou’ team reveals a novel mechanism by which the prefrontal cortex–hypothalamic paraventricular nucleus neural circuit regulates social avoidance and fear memory. Brain_VTA offers AAV packaging services. www.nature.com/articles/s41...

❗News︱Brain 👏Prof. Zhifang Dong’s Team reveals a novel mechanism by which SMG7 deficiency induces autism-like behaviors through the abnormal accumulation of PKD1. 👇MORE academic.oup.com/brain/advanc...

❗News︱Brain 👏Prof. Zhifang Dong’s Team reveals a novel mechanism by which SMG7 deficiency induces autism-like behaviors through the abnormal accumulation of PKD1. 👇MORE academic.oup.com/brain/advanc...

❗Honored to be cited in Translational Psychiatry 👏Prof. Wenting Wang’ team reveals the cortico-striatal circuit mechanism by which imminent threats drive the switch in defensive responses. Brain_VTA offers AAV packaging services. www.nature.com/articles/s41...

❗Honored to be cited in Nature Communications 👏Prof. Wei Xie’ team discovered that the autism-associated molecule NLG1 regulates the formation of social memory in mice via CCK interneurons in the dCA2 region. Brain_VTA offers AAV packaging services. www.nature.com/articles/s41...

❗News︱Neuron 👏Prof. Yanjiang Wang’s Team reveals that liver-targeted expression of APOE3Ch enhances Aβ clearance and alleviates Alzheimer's disease-related brain pathology. 👇MORE www.cell.com/neuron/abstr...

❗News︱Nature Communications 👏Prof. Jianzhi Wang’s Team has revealed that microglial CD31 inhibits Aβ clearance and promotes pathological progression in Alzheimer's disease, and has identified the bioactive peptide P1 as a potential therapeutic candidate. 👇MORE www.nature.com/articles/s41...

👏Neural mechanisms underlying the stress-to-anxiety transition! Prof. Jing Han’ team reveals how the stress-specific activation of a neuronal population in the hypothalamic supramammillary nucleus drives anxiety-like behavior. Brain_VTA offers AAV services. elifesciences.org/articles/108...

❗Honored to be cited in Advanced Science 👏Prof. Yan Sun’ team Reveals the Epigenetic Mechanism by Which ANKS1B Regulates the Escalation of Cocaine Intake. Brain_VTA offers AAV packaging services. advanced.onlinelibrary.wiley.com/doi/10.1002/...

❗News︱Nature Neuroscience 👏Prof. Hanfei Deng’s Team Uncovers Brainstem Circuit Mechanisms Underlying Vagal Nerve Stimulation’s Regulation of Pain and Negative Emotions. 👇MORE www.nature.com/articles/s41...

❗News︱Molecular Psychiatry 👏Prof. Yonggang Yao’s Team Uncovers the Molecular Mechanisms of Polygenic Synergistic Pathogenesis in Alzheimer's Disease. 👇MORE www.nature.com/articles/s41...

❗News︱Advanced Science 👏Prof. Fei Xiao’s Team Uncovers a Novel Mechanism by Which Histone H3K18 Lactylation Regulates the E3 Ubiquitin Ligase COP1 in Temporal Lobe Epilepsy. 👇MORE advanced.onlinelibrary.wiley.com/doi/10.1002/...

❗News︱Advanced Science 👏Prof. Chenggeng Peng’s Team Discovers a Novel Mechanism and Potential New Drug for Chronic Neuropathic Pain. 👇MORE advanced.onlinelibrary.wiley.com/doi/10.1002/...

❗News︱Nature Communications 👏The Glial Code of Empathy! Prof. Xiaoping Tong’s Team Reveals How NG2 Glia in the MeA Region Regulate Vicarious Post-Traumatic Prosocial Responses via GABA Signaling. 👇MORE www.nature.com/articles/s41...

❗Honored to be cited in Mol Psychiatry 60% Nitrous Oxide Can Induce Reward-Seeking Behavior! 👏Prof. Tengfei Ma’ team Reveals a Novel Mechanism Underlying the Deep Cerebellar Nuclei–Ventral Tegmental Area Dopaminergic Circuit. Brain_VTA offers AAV packaging services. www.nature.com/articles/s41...

❗News︱Nature Communications 👏New Animal Model! Prof. Peng Yin’s Team Develops a Novel Mouse Model Capable of Mimicking TDP-43 Pathology and ALS-like Phenotypes. 👇MORE www.nature.com/articles/s41...

❗News︱Phytomedicine 👏Prof. Zhijun Zhang’s Team Uncovers a Novel Mechanism by Which Costunolide Targets Keratinocyte Signaling Pathways to Alleviate Inflammation and Pruritus in Atopic Dermatitis. 👇MORE www.sciencedirect.com/science/arti...