Today on the World Cancer Day, we are highlighting the work of our partner Ambusol. Meet Ambusol's CEO Maximilian Telander and learn about their ambition to create new high precision therapeutics targeting gliblastoma. 👉 www.fluicell.com/news/changin...

The Cantu-syndrom H60Y mutation in the SUR2 subunit of ATP-sensitive potassium channels results in gain of function only when paired with Kir6.1. New Dynaflow publication in Journal of Biological Chemistry. 👉 www.jbc.org/article/S002... @asbmbjournals.bsky.social #science #patchclamp #ionchannels

Big congratulations to Raquel Conde Holtzmann on receiving Second Prize in the ESPCI Alumni Internship Awards for her work with us on developing high throughput microfluidic cardiac screening platforms. It was a joy having you on our team and we are excited to follow you on your future journey.

We installed a Biopixlar bioprinting system at @crick.ac.uk this week. Big thanks to amazing team at Making Lab for the smooth setup and warm welcome. Getting to see your facilities firsthand and hear about your research has been truly inspiring.

How can tissue engineering and biofabrication technologies advance cancer research? In a new review, Bertassoni and coworker explore how early cancer models facilitate a transition from treating to intercepting disease.

In recognition of the breast cancer awareness month, we are highlighting research that pave the way for new breast cancer treatments. Here, Trkulja et al present a method for designing antibodies for undruggable targets such as KRAS, whihch is implicated in TNBC. www.science.org/doi/10.1126/...

“Some of my proudest moments as a researcher have been when I have been able to solve problems by going back to my notes to figure out the cause.” 👋 Meet Anton Rydberg and find out how applying a scientific mindset has value in both research and training. 🔗 www.fluicell.com/people/anton...

🧪 Want to combine bioprinitng and single-cell spatial transcriptomics? In a new paper in STAR Protocols, researchers at @ohsuknight.bsky.social present at method for spatial transcriptomics adapted for in vitro systems in 2D. 🔗 www.sciencedirect.com/science/arti...

🔬 Last week we had the great pleasure of opening a new part of our lab at Fluicell focused on extended tissue and cell culture studies. This new space further enhances our ability to analyze tissue development, cell function and cell survivability over time.

🔬 Last week we had the great pleasure of opening a new part of our lab at Fluicell focused on extended tissue and cell culture studies. This new space further enhances our ability to analyze tissue development, cell function and cell survivability over time.

👋Join us in welcoming Rosa Lacordaire and Charlotte Cany from @espciparispsl.bsky.social who are doing a research internship with us. Supporting young researchers is an important part of Fluicell’s commitment to building the future of life science, and we’re excited to follow their progress.

We are excited to announce that we are partnering with Ambusol to create groundbreaking new ways to treat cancer. Leveraging our microfluidic technology, we are developing a novel type of device for high precision drug delivery directly to the tumor. 🔗 www.fluicell.com/news/fluicel...

🚀 We are excited to announce that we have received funding from Breakthrough T1D for a collaboration to develop type 1 diabetes tissue therapeutics. The collaboration combines our Nexocyte platfom with unique stem cell material to build designer islets for type 1 diabetes treatment.

🚀 We are excited to announce that we have received funding from Breakthrough T1D for a collaboration to develop type 1 diabetes tissue therapeutics. The collaboration combines our Nexocyte platfom with unique stem cell material to build designer islets for type 1 diabetes treatment.

🧪 Researchers at @uofcalifornia.bsky.social have discovered new ways to selectively target specific voltage-gated sodium channels, affecting neuronal excitability. Their results can enable more precise ways to treat epilepsy and other neurological conditions. 🔗 www.fluicell.com/news/selecti...

🧪 Researchers at @uofcalifornia.bsky.social have discovered new ways to selectively target specific voltage-gated sodium channels, affecting neuronal excitability. Their results can enable more precise ways to treat epilepsy and other neurological conditions. 🔗 www.fluicell.com/news/selecti...

🧪Are you attending #AACR25? Make sure to check out the poster "Bioprinting 3D spatially resolved tumor avatars to mimic the native tumor microenvironment" presented by Haylie Helms of @ohsuknight.bsky.social (abstract nr LB161). 🔗 aacrjournals.org/cancerres/ar... #CancerResearch #Bioprinting

A stunning example of biological complexity and the important relationship between tissue microstructure and function

Last week, the BIRDIE project organized a workshop to discuss how to bring in vitro research models from bench to business. You can now watch a recorded version of the workshop, giving you the chance to learn more about organ-on-chip standardization, bioethics and in vitro model commercialization

We are excited to announce that our technology for generating three dimensional biological tissues has been granted a patent in the EU. The technology is the foundation for our tissue-based products for regenerative medicine and drug development targeting type 1-diabetes and cardiac disease.

Can light be a tool for labeling living cells? In a new study from researchers at @harvard.edu and Chinese Academy of Medical Sciences, Sarah Innes-Gold et al. present a method for light-activated cell labeling with high precision. Read more on our website. 🔗 www.fluicell.com/news/scienti...

Owe Orwar and team have created a biohybrid random access memory based on patch-clamped GABA receptors placed in an open volume microfluidic device, generating laminar agonist patterns. The receptors read and store the chemical input signals as state distribution. #JournalClub #Biohybrid #Dynaflow

Resolving GPCR-kinetics is key for understanding how external stimuli is converted to cellular response. Using FRET, Carsten Hoffmann and team study how CXC chemokine receptor 4 ligands affect activation, revealing distinct mechanisms that reflect pharmacological properties. #JournalClub

Resolving GPCR-kinetics is key for understanding how external stimuli is converted to cellular response. Using FRET, Carsten Hoffmann and team study how CXC chemokine receptor 4 ligands affect activation, revealing distinct mechanisms that reflect pharmacological properties. #JournalClub

Great to see the diversity of approaches when it comes to addressing biofabrication challenges such as tissue resolution, scalability and functional control! We need a breadth of new technologies to fully realize the potential of biofabrication within therapeutics and drug development.

Today is International Day of Women & Girls in Science. Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM

McKerrall has used structure- and ligand-based design principles to discover a new series of Nav 1.7 inhibitors. Through compound optimization, the researchers were able to select a highly potent and metabolically stable, subtype selective Nav1.7 inhibitor for further studies in vivo #JournalClub

🧪 On March 12, the BIRDIE consortium is gathering experts in organoids, organ-on-chip technology and kidney disease to discuss how andvanced in vitro models can transform drug development and biomedical research. 👉 birdieproject.eu/2025/02/07/f... #OrganOnChip #Science #Bioprinting #KidneyDisease

McKerrall has used structure- and ligand-based design principles to discover a new series of Nav 1.7 inhibitors. Through compound optimization, the researchers were able to select a highly potent and metabolically stable, subtype selective Nav1.7 inhibitor for further studies in vivo #JournalClub

Surface interactions likely played a key role in the emergence of the first living cells. Köksal et al. show that phospholipids deposited on Hadean Earth material analogs spontaneously form compartments that encapsulate DNA/RNA and enable non-enzymatic strand replacement reactions. #JournalClub

Surface interactions likely played a key role in the emergence of the first living cells. Köksal et al. show that phospholipids deposited on Hadean Earth material analogs spontaneously form compartments that encapsulate DNA/RNA and enable non-enzymatic strand replacement reactions. #JournalClub

Amazing achievement setting a clear path forward for future cell-based treatments of cardiac diseases.

Cardiovascular diseases are responsible for one third of all global deaths but represent only five percent of newly approved drugs. Using our human tissue technology, we are creating next-generation research solutions to transform the way we treat heart disease. 👉 www.fluicell.com/pipeline/hea...

Controlling the environment inside cells is a major challenge. Olofsson et al. have created a pore formation method for microfluidic single-cell solution exchange that makes it possible to initiate enzymatic reactions and to generate intracellular oscillations and gradients. #JournalClub #PatchClamp

Controlling the environment inside cells is a major challenge. Olofsson et al. have created a pore formation method for microfluidic single-cell solution exchange that makes it possible to initiate enzymatic reactions and to generate intracellular oscillations and gradients. #JournalClub #PatchClamp

When feeding, mosquitoes need to distinguish between blood and nectar. Jové et al. show that mosquitoes use specialized neurons, tuned to specific blood components to steer feeding behavior. The findings provide valuable insight for understanding vector-born disease transmission. #JournalClub

When feeding, mosquitoes need to distinguish between blood and nectar. Jové et al. show that mosquitoes use specialized neurons, tuned to specific blood components to steer feeding behavior. The findings provide valuable insight for understanding vector-born disease transmission. #JournalClub

Ion channels are central in many diseases but are challenging as drug targets. Using TRPV1 as an example, Trkulja et al. present a method based on limited proteolysis to identify functionally important regions, providing a means to target proteins that have been considered undruggable. #JournalClub

Bioelectronic integration creates exciting opportunities for innovation across areas such as biosensing and cell therapy. Check out this comprehensive review by @jrivnay.bsky.social et al. to learn more about the many possible future applications that this technology enables.

Compartmentalization is a core feature of living cells. In this paper, Köksal et al. show how lipid nanotubes facilitate spontaneous formation of membrane compartments. Their results reveal mechanisms that could have contributed to the evolution of life on earth. 🧪 #JournalClub #Microfluidics

Monitoring ion signals on the cell exterior is a major challenge in biosensing. Burgstaller et al. have developed a biosensor combining biotinylated cell surface tags with recombinant fluorescent probes, providing a versatile approach to measure cell processes non-invasively. #JournalClub #BioPen

As many more stem cell therapies enter the clinic, the development within the field will be exciting to follow. We see great opportunities for cell therapy in areas such as diabetes and heart disease, but also many challenges that need to be addressed before they can reach their real potential.

Fluicell’s tissue products are enabled by our microfluidic bioprinting technology that makes is possible to build tissues with single-cell resolution, without bioink. In this paper, Jeffies et al. show the compatibility of the technique across a wide range of cell types. #JournalClub #Bioprinting

💜 Tissue microarchitecture! Such and incredible achievement and what a fantastic resource for future research.

Amazing resource for all scientists out there who sit on groundbreaking research data but struggle to express it visually!

🌟 This past Friday we said goodbye to our interns Claire and Rachel from ESPCI, Paris, with a not so traditional Lucia celebration. 🙌 It has been an absolute privilege and a great joy to have you on our team and we wish you the best of luck on your journey ahead.

Fast inactivation is an essential part of voltage gated sodium channel function, and its disruption is linked to multiple diseases. Clairfeuille et al. use a scorpion toxin that impedes fast inactivation to gain structural insights into the inactivation process and toxin pharmacology. #JournalClub

Compartmentalization is a core feature of living cells. In this paper, Köksal et al. show how lipid nanotubes facilitate spontaneous formation of membrane compartments. Their results reveal mechanisms that could have contributed to the evolution of life on earth. 🧪 #JournalClub #Microfluidics

🧪 Fluicell’s microfluidic technology is used in multiple labs across the world. Check out our publication library and discover how our research innovations have contributed to new knowledge about cancer, pain, mosquito neurobiology, and even the origin of life — just to name a few areas. 👇 #science

💜 We are excited to announce that a patent covering our unique microfluidic bioprinting technology has been granted in the EU. The patent is an important step forward in our mission to provide the next generation of tissue solutions for drug development and regenerative medicine. #bioprinting