Our paper on the anti-cancer effects of the first-in-class plectin inhibitor plecstatin is out in @MolOncology! Great work by @OutlaZuzana & @Kosla_Jan. Collaborations with @Selma_OsMyers (@MedUniWien), Sam Meier (@univienna) & Lukas Frick (@UZH). Check at pubmed.ncbi.nlm.nih.gov/41467448/

It’s been an eventful year for all of us! Our Christmas party was a great reminder of the team spirit behind the science & we’re excited to take on the challenges of 2026. Merry Christmas & Happy New Year from the Laboratory of Integrative Biology!

At #WMS2025 in Vienna? Check out our PhD student Vera Getmanchuk-Zaporoshchenko’s poster on phenotyping a preclinical model of plectin-related LGMD. #LGMD #MuscularDystrophy"

Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social

Two hours of tough work to make 2 minutes of science sparkle ✨ Today we helped popularize our #magnetogenetics manuscript by Gemperle Jakub for NUVR_CZ. Tune in to TV NOVA evening news!

“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; ‪@gregorlab.bsky.social‬) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!

"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10.... @imgprague.bsky.social #3Dmatrix #CellBiology @science.org

Huge congratulations to our PhD student Srikant Ojha for winning the Microscopic Picture of the Year 2024/2025 award! Well deserved!

30th Cytoskeletal Club was opened in Liblice on Monday, 28 April. The first day is complete - great keynote by Martijn Gloerich (@GloerichLab) from @UMCUtrecht on Mechanical control of epithelial cell division. More to come!

Great 2 days at MedUni Vienna hosted by @Selma_OsMyers from Institute of Medical Chemistry and Pathobiochemistry. Giving a seminar on our concept of targeting mechanical homeostasis in cancer. Great meeting the Lilli Winter and Osmanagic-Myers Labs. Evening with our mentor Gerhard Wiche.

Excited to share our new @elife.bsky.social in collaboration with @Schiller lab.: Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis doi.org/10.7554/eLif... #ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics

Happy Monday... Happy to share the picture of our colleague Srikant Ojha winning EuBI Node Picture of the Month 2024/25 competition! (imcf.natur.cuni.cz/IMCF/picture...)

Excited to share our new @elife.bsky.social paper! We show that plectin fuels the growth & metastasis of hepatocellular carcinoma (HCC). Targeting plectin could be promising in HCC therapy, as we show using a novel plectin inhibitor, plecstatin! elifesciences.org/articles/102... #plectin #HCC

Hello! The Martin Gregor lab @imgprague is now on Bluesky! We will tweet about our #mechanobiology work, pretty microscopy images and videos and more. FOLLOW us!