Yudong Gao (@yudonggao.bsky.social)

The existence of specialized phosphatases in regulating the AIS was unclear. In this initial report, we show that a PP2A subunit is enriched at the AIS and contributes to its local phosphoregulation. Fun collaboration with Dr. Matthew Rasband's lab, and thanks to all authors for their contribution!

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A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment - Nature Communications The existence of phosphatases specialized in regulating the axon initial segment (AIS) was unclear. Here, the authors show that a PP2A-B55 subunit is selectively enriched at the AIS and contributes to... https://www.nature.com/articles/s41467-025-66120-0