Something Strange Happens When You Trace How Connected We Are Watch our latest video, in full, on YouTube - youtu.be/CYlon2tvywA

1500 on Lichess for the first time 🥳

Today I learned about "Favrile glass", an opalescent glass. Much prettier live than in the photo, sadly fell out of fashion in the 1910s

We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products. Apply here: www.wur.nl/en/vacancy/p... Please share!

TIL. Iconic pictures en.m.wikipedia.org/wiki/Yousuf_...

Just finished reading "The Alchemy of Air" by Thomas Hager. An unexpected find (a Canadian copy purchased second hand in Brazil!) with a really well written account of possibly the most impactful chemical reaction discovered by man. I definitely recommend it

essa é nova, primeiro de Abril fora de hora?

Repurposing might be one of the best uses of AI in drug research. Just feed it all the knowledge available and hope for the best 😅 Doctors Told Him He Was Going to Die. Then A.I. Saved His Life. www.nytimes.com/2025/03/20/w...

I'm Still Here wins Best International Feature Film at the #Oscars This is the first win for Brazil in this category.

‘Ainda Estou Aqui’ ganha Oscar de melhor filme internacional glo.bo/41BZ8aV

The 2025 Chemistry Faculty Jobs List has 486 tenure-track positions and 85 teaching positions: bit.ly/facultychemj... #facultychemjobs #chemjobs #chemsky 🧪⚗️

Saving 30% energy use for Linux servers seems massive. uwaterloo.ca/computer-sci...

Nice video by Veritasium on AlphaFold2 www.youtube.com/watch?v=P_fH...

New version of our #Trypanosoma cruzi pre-print is now online. Includes new analysis on UTR complexity and reveals cell-specific repertoires for surface protein families, which may play an important role in the immune evasion strategy of this pathogen. www.biorxiv.org/content/10.1...

Nice going back to Duolingo, although to a different language

Just came back from the university observatory. This was the "Martian week", but unfortunately they couldn't point the big telescope to observe Mars due to bad weather. Still, there was a small one pointed at Jupiter, and 4 of its moons were visible, so cool

The next Cambridge Cheminformatics Newsletter, December 2024 Edition is out! Containing upcoming related events, news jobs and resources For details please see: www.drugdiscovery.net/2024/12/22/c... Have a good Christmas/Holiday period everyone! All the best and see you in 2025, Andreas

Best Practices in Python Package Development education.molssi.org/python-packa...

My mom's flower vase with three species that open and close the flowers throughout the day. Pics taken from 5 am to 5 pm

Looking for a post-doc? Come work with us + one of the amazing advisors from top university labs. Deadline soon - in February!

So nice to learn about this. A much needed Dengue vaccine, developed in Brazil www.thelancet.com/journals/lan...

We've a postdoc opening for our lab at the Broad: Cambridge MA! Must have experience in toxicology + data science Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models! broad.io/mlcbpostdoc

Since I’m still laid up sick at home, I’ll show you this little goofball molecule from the pharmacopeia: benzonatate. This drug, for cough, is orally administered with a rapid onset (15-20 min) and up to 8 hour duration of action. 1/

Hey 👋 I'm new here and I did my best to compile some starter packs to help other new people in the same community! I probably missed some people so please help me update my lists :) 1/6 Machine learning for drug discovery go.bsky.app/2PpxWLc More in the thread! 🧵

Scientific machine learning starter pack go.bsky.app/9a1GVeq

From time to time even top journals publish howlers and Voltaire might have encouraged bloggers to post “pour encourager les autres” (re-post) #MedChem #cheminformatics #DrugDesign #DrugDiscovery #chemsky 🧪 fbdd-lit.blogspot.com/2024/07/a-no...

Here's a Cheminformatics Starter pack! Let me know if you would like to be added! And more importantly, do encourage people to join the blue skies :D

The first website was published 34 years ago today. Here it is:

I'm glad it worked in the end, and hope it all helps in developing new treatments www.nature.com/articles/d41...

I think this sums up perfectly my thoughts on LLMs for chemistry: "Given the availability of numerous domain-specific tools, why would anyone opt to use a general-purpose LLM for molecule generation? " practicalcheminformatics.blogspot.com/2024/10/sill...

Well written and very relevant for drug designers Do Enthalpy and Entropy Distinguish First in Class From Best in Class? www.ncbi.nlm.nih.gov/pmc/articles...

Nice discussion about the Future of AI in Drug Discovery www.collaborativedrug.com/cdd-blog/htt...

Not today, but maybe soon 😂

How to bring to market a drug that won't turn a profit... www.nature.com/articles/d41...

Important points raised at the Polaris talk at MOML 2024 regarding aspects of modelling in chemistry that go beyond getting good metrics. I'm watching the recording of the event here: www.youtube.com/watch?v=LPYk...

More tools to help chemists think outside the box are always welcome. AiZynth impact on medicinal chemistry practice at AstraZeneca. pubs.rsc.org/en/content/a...

#ChemPostDoc #chemsky 🧪

Two consecutive days with news about pig organ transplant (liver and kidney). Excellent news for us!

It’s time to admit that genes are not the blueprint for life www.nature.com/articles/d41...

A number of articles in Drug Resistance in Infectious Diseases and Beyond (virtual special issue in ACS Infectious Diseases) are #OpenAccess #MedChem #DrugDiscovery #chemsky pubs.acs.org/page/aidcbc/...

A fascinating topic. If you also think so, there is a course on Coursera called "What a plant knows" that goes over how plants communicate and sense the world. Mindblowing Video of Plants Talking to Each Other In Real Time www.youtube.com/watch?v=hd-h...

Opportunity for computational chemist at University of Texas MD Anderson Cancer Center (Houston TX USA) #CompChem #cheminformatics #CompChemJobs #ChemJobs jobs.mdanderson.org/search/jobde...

Connections Puzzle #220 🟩🟩🟩🟩 🟨🟨🟨🟨 🟦🟦🟦🟦 🟪🟪🟪🟪 Spoiler alert: a cheminformatician might have been involved in today's puzzle 😅

Opportunity for computational chemist at Isomorphic Labs (London UK) #CompChem #cheminformatics #UKChemJobs #ChemJobs boards.greenhouse.io/isomorphicla...

purple first, that's a first... Connections Puzzle #215 🟪🟪🟪🟪 🟩🟩🟩🟩 🟨🟨🟨🟨 🟦🟦🟦🟦

...H-bond donors in solute molecules will be preferentially solvated by octanol over water, leading to an over-estimation of the lipophilicity of compounds containing H-bond donors. mcconnellsmedchem.com/2024/01/08/l...

Interesting - Fluorination of an HCV protease inhibitor improves activity against resistant variant www.sciencedirect.com/science/arti...

WTF? What made medicinal chemists think of using fluorine, given its fraught history (the fluorine martyrs?!?)? My latest Thesis column in Nature Chemistry rdcu.be/dt42o