Oleg Mikhajlov (@mikhajlov-oleg.bsky.social)

1/11 🚨 New research! 🚨 We explored how cells adhere to supported lipid bilayers (SLBs) using Invasin, a high-affinity integrin ligand. Surprisingly, cells spread and form mature integrin adhesions on fluid SLBs, revealing a novel microtubule-driven mechanotransduction! www.nature.com/articles/s41...

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Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction - Nature Communications During cell adhesion, integrins are typically thought to require immobilized ligands for spreading. Here, the authors demonstrate that cells can spread and form mature integrin adhesions on fluid subs... https://www.nature.com/articles/s41467-025-56343-6