(1/3) In this study, led by Knowledge Translation Program Scientist Dr @andreatricco.bsky.social, the team looked at the comparative safety and effectiveness of cognitive enhancers for Alzheimer’s disease. 🔗 bit.ly/ADmeds @averoniki.bsky.social @sporalliance.bsky.social

June Issue Online. With: Editors' Choice June 2025 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Development and validation of crosswalks between the EORTC QLQ-C30 physical, role, social and emotional functioning, fatigue and global health status/ quality of life scales and their corresponding PROMIS scales - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Psychometric properties and reference values of the Patient-Reported Outcomes Measurement Information System (PROMIS®) pediatric item banks Mobility, Upper Extremity and Pain Interference in the Dutch population - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

The performance of small sample correction methods for controlling Type I error when analysing parallel cluster randomised trials: a systematic review of simulation studies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Enhancing Risk Prediction base on Health Administrative Data Using High-Dimensional Prediction Model - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Integrating Personomics into Precision Medicine - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A methodological review of network meta-analyses applied to complex interventions for public health and a typology of the node-making process - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Prevalence of patient and public involvement in child health randomized controlled trials and impact on research quality, loss to follow-up, and dissemination - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Where are the harms? Underreporting of adverse events in clinical trials investigating targeted therapy for endocrine and metabolic disorders: an observational study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Eeek this makes for a grim read..... - Serious AEs (SAEs) and other AEs (OAEs) results omitted in 14% and 9% of articles, respectively - All-cause mortality missing in over 1/3 of articles - And when AE data was complete, discrepancies in 38% of SAEs, 86% of OAEs, and 36% of mortality outcomes

July issue is out with: Editors’ Choice: July 2025 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

NEW PAPER in @jclinepi.bsky.social looking at the content of open peer-review reports of RCTs in the field of oncology www.jclinepi.com/article/S089... Peer review reports [...] were short (median 276 words), superficial, and rarely constructive #metascience #peerreview #RCTs

Methods for living guidelines: paper 6: insights from Australian Living Evidence Collaboration's (ALEC) use of existing systematic reviews in living guideline development - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Meta-research on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Meta-research on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

The performance of small sample correction methods for controlling Type I error when analysing parallel cluster randomised trials: a systematic review of simulation studies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A methodological review of network meta-analyses applied to complex interventions for public health and a typology of the node-making process - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Clusters of post-acute COVID-19 symptoms: a latent class analysis across 9 databases and 7 countries - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guidance for intervention fidelity in non-drug, non-surgical trials: a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Experiences and challenges faced by systematic review authors in using the GRADE approach: a qualitative study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Target trial emulation of cardiovascular outcome trials of medications used to treat type 2 diabetes using real-world data: A systematic review of observational studies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

The Overview Reporting Map: a Visual Tool for Overviews of Systematic Reviews - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Living recommendations do not ‘flip-flop’ - Examining the probability of directional changes to recommendations in living guidelines - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Adherence to RECORD reporting guidelines among observational studies using routinely collected health data published in general medical journals: a meta-epidemiologic study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Instruments lacking comprehensive validation dominate research on researcher behavior: a scoping review based on the COM-B model - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Is frailty incremental to the 4C Mortality model for mortality risk prediction in hospitalized older individuals with COVID-19 disease? - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Effect of pre-end-stage kidney disease nephrology care on the association between neighborhood poverty and referral for kidney transplantation among patients with end-stage kidney disease - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Content validity: judging the relevance, comprehensiveness and comprehensibility of an outcome measurement instrument – a COSMIN perspective - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Adverse events are considered but not always explicitly selected as core outcomes in research: an updated systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Metformin to treat breast cancer: An application of the prevalent new-user design for observational studies with no active comparator - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Clinical study report data did not substantially alter point estimates but improved precision in a nephrology systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Individual participant data informed risk of bias assessments for randomised controlled trials in systematic reviews and meta-analyses - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

#CochraneDaily Just published! Study of 87 #Cochrane reviews from 2019 (60) & 2023 (23) that included non-randomized studies of interventions found low adherence to guidance: 36 justified including NRSI & 25 used ROBINS-I for risk of #bias www.jclinepi.com/article/S089... @jclinepi.bsky.social

Balancing Methodological Rigour and Simplicity: Is Optional Assessment of Bias Domains the Ideal Path Forward? - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Our new journal metrics!

Clinical study report data did not substantially alter point estimates but improved precision in a nephrology systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Balancing Methodological Rigour and Simplicity: Is Optional Assessment of Bias Domains the Ideal Path Forward? - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Peer review reports of randomized controlled trials in oncology can be short and superficial - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A Population-based Recalibration Method for Updating Survival Neural Networks Models for Cardiovascular Risk Prediction in UK and China - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Comparison of AI-assisted and human-generated plain language summaries for Cochrane reviews: protocol for a randomised trial (HIET-1) - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A microsimulation model based on healthcare pathways to estimate the impact of COVID-19 pandemic-induced delays on breast cancer mortality - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Anchor-based predictive modelling and receiver operating curve estimates of patient acceptable symptom state for the forgotten joint score in total knee arthroplasty patients stratified by age and gender. - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Review of methods to deal with the misalignment of times of eligibility, start of follow up and treatment assignment in studies explicitly aimed at emulating target trials - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Assessment of Traditional and Novel Effect Measures for Time-to-Event Endpoints: a meta-epidemiological study of published oncological trials - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Improving the Reporting and Use of Trial Results in Clinical Trials Registries: Global Practices, Barriers, and Recommendations - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

External validation, impact assessment and clinical utilization of clinical prediction models: a prospective cohort study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

New paper in @jclinepi.bsky.social led by my super cool PhD student @kahin-tai.bsky.social with the SHARE-CTD (@sharectd.bsky.social) crew. It is the 2nd paper in a “JCE trilogy” on data sharing by SHARE-CTD: the 1st one addressed the topic in broad terms, and the third will focus on data reuse.

#CochraneDaily Just published! Study from NHMRC Clinical Trials Centre @sydney.edu.au‬ provides guidance for using individual participant data to inform risk of bias assessments in #IPD meta-analyses www.jclinepi.com/article/S089... #EvidenceSynthesis #RiskOfBias #Bias @jclinepi.bsky.social

⭐New publication alert⭐ 'Comparison of established comorbidity scores using administrative data of patients undergoing surgery or interventional procedures in Massachusetts ' published in the July issue of @jclinepi.bsky.social. ➡️ Read journal article: www.jclinepi.com/article/S089...