Sitting in the Diabetic Kidney Disease session at #PAS2025. Cherry Mammen presenting on AKI in DKA. Approx 50% of DKA have AKI, and approx 28% have severe AKI. RRT is uncommon (4%) but neurocog outcomes are poorer at 3-6 months.

This week I ticked ‘Singing a social media reference during a symposium presentation at a national conference.’ Off my bucket list! #PSANZ

Some sunset zen from my ride home yesterday. @cityofmelbourne.bsky.social #bike

On behalf of the ANZ NKC Chapter, thank you thank you thank you #PSANZ2025 🙏🙏🙏. Huge attendance and great discussion at our symposium today!!! We were just blown away by the enthusiasm and engagement from you all to improve our care and research into neonatal kidney disease.

It’s time!!! The Inaugural Neonatal Nephrology Symposium kicking off to a full house at #PSANZ2025! First up Simon Carter from RCH Melbourne discusses antenatal counselling of antenatally detected kidney disease. #NKC #ANZNKC #preservethenephrons

Very grateful for the opportunity to present our local data-led audit of #AKI at #PSANZ2025. Work made possible by the coding expertise and supervision of Emily See and the amazing resource that is the Centre for Health Analytics at the Melbourne Children’s Campus.

Smells interesting!!

Very excited to have landed in Brisbane (a little late, sorry) for #PSANZ2025 to talk all things neonatal kidney with my colleagues from the ANZ Chapter of the Neonatal Kidney Collaborative - welcoming new members (free - link below - all welcome). #PSANZ www.babykidney.org/chapters/aus...

🎧 In our latest episode, our panel of nephrology and oncology experts tackle: ✔️ AKI in cancer patients ✔️ The impact of novel oncology therapies ✔️ Drug dosing considerations in kidney-compromised cancer patients Listen here: bit.ly/3DamjQ9 @silvishah.bsky.social @gudnephron.bsky.social

This #WorldKidneyDay 's theme is "Are your kidneys OK? Detect early, protect kidney health.", In this editorial Dave Selewski and I ask the question, how can we best find and screen pediatric populations at risk of CKD? www.sciencedirect.com/science/arti...

In this podcast, ahead of World Kidney Day 2025, I discuss why preterm birth and post-natal kidney injury can lead to increased mild kidney disease risk in adulthood. Early detection and treatment can reduce progression. www.podbean.com/ew/pb-zr9r3-...

COL4A5 Intronic Variants at Third to Fifth Nucleotides Cause Alport Syndrome pubmed.ncbi.nlm.nih.gov/39990911/

All patients with Dent’s (and presumably Lowe’s) Disease should be screened and treated for low vitamin A. This can drop because of loss of retinol binding protein and when severe can have permanent effects on their vision. #IPNA2025

Ana Cristina Simoes E Silva presents the recently published (NDT) CPG for the management of Dent’s Disease. academic.oup.com/ndt/advance-...

Dr Julien Hogan presents results of RCT in children with FR nephrotic syndrome treated with Rituximab +/- IVIG. Result: Addition of IVIG showed no benefit on relapse free survival. #IPNA2025

Aurelia Bertholet Thomas speaking now on cystinuria. Type A SLC3A1 is more common (and sometimes associated with a contiguous gene deletion including PREL1), and SLC7A9 less common. #IPNA2025

Emerging stone forming monogenic kidney diseases with David Sas from Mayo Clinic. #IPNA2025

Gaya Raman presenting at the Bladder and Continence Grand Round. Rushing for the 7am start of this session I could certainly benefit from optimising my bladder capacity right now! #IPNA2025

Tammy Brady just gave the most outstanding interactive workshop on blood pressure measurement at #IPNA2025. Things you mightn’t know can increase the blood pressure, crossed legs, watching the phone, TALKING!!

@louiseoni.bsky.social on Lupus Nephritis to close out this amazing session. #IPNA2025 Glom Dis update.

Matko Marlais presenting on RPGN in paediatrics in the glomerular disease update. #IPNA2025

#IPNA2025 Glom disease sesh. MN - Hogen Julian. Most present in teenage years with normal kidney function, proteinuria and 70% with micro-haematuria. 50% C3+. IgG1/4 -primary. C1q - consider LN.

Dr Moin Saleem: What are the main hurdles to success for gene therapy of monogenic nephrotic syndromes? #IPNA2025

Moin Saleem discusses the potential for genetic therapies for podocin associated nephrotic syndrome, using pod cure specific promoters to overcome some of the difficulty in cell specific delivery in the kidney. #IPNA2025

Moon Saleem discusses genetic drivers of steroid sensitive nephrotic syndrome, and steroid resistant NS, the latter having some risk alleles that may predict for FSGS in the absence of a monogenic cause. #IPNA2025

Michelle Rheault presents the Update in Genetic Diseases #IPNA2025 on treatment developments in Alport Syndrome. First message, Alport Syndrome variants (particularly dominant AS) are more common than previously thought. @rheaultm.bsky.social

Stepping in at the last minute for @dnoone.bsky.social who had flight delays from Toronto is @cathyquinlan.bsky.social! (and she’s doing a fabulous job giving someone else’s talk) #IPNA2025

@cathyquinlan.bsky.social takes to the podium with only hours notice to deliver another speaker’s talk (due to travel delays), with aplomb! Her brain is the biological equivalent of an AI program. #IPNA2025

Dr Hugh McCarthy: What if we did genetic testing on all children with ESKD? Chinese study shows hit rate of 46.7% #IPNA2025 pubmed.ncbi.nlm.nih.gov/39363361/

Hugh McCarthy highlights how heterozygous variants in genes traditionally thought to cause kidney disease risk only in a recessive fashion, may increase risk for potential kidney donors. Which other genes might this apply to in the future? Will all donors be screened in time? #IPNA2025

A nice rubrik from Hugh McCarthy regarding how to consider the risk of donation for donors of children with genetic kidney disease. Lots of opportunity for improved knowledge and guidance here. #IPNA2025

Matt Sampson identifies a modifier (p.N264K) of the APOL1 G2 allele that protects against the M1 risk of kidney disease. Screening for this “M1” modifier would help identify patients for stronger investigation of kidney disease and may help clear parents as donors. #IPNA2025

Lisa Guay-Woodford asks if we could develop a disease severity index fro ARPKD similar to that developed for ADPKD by Emelie Cornec Le Gaull et al (below). It will be hard, but would be so useful to antenatal counselling. #IPNA2025 pubmed.ncbi.nlm.nih.gov/26150605/

Excited to be in Cape Town at the 20th IPNA Congress. @ped-neph.bsky.social So excited to be here to catch up with colleagues and hear the latest in children’s kidney disease, having not been to IPNA for 12 years! Photos of our safari yesterday and the spectacular geography around Cape Town.