@marialukarska.bsky.social
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reposted by
Owen Tuck
2 months ago
Excited to finally share this work! We noticed a pair of genes - a nuclease and a protease - shuffles between antiviral systems. We show how proteolysis activates the nuclease, triggering defense in known and unknown immune contexts.
tinyurl.com/2uwwy4ty
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Recurrent acquisition of nuclease-protease pairs in antiviral immunity
Antiviral immune systems diversify by integrating new genes into existing pathways, creating new mechanisms of viral resistance. We identified genes encoding a predicted nuclease paired with a trypsin...
https://tinyurl.com/2uwwy4ty
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Check out our pre-print on ProteinGuide, a new method for conditioning protein generative models on experimental data! Thanks to the amazing team:
@junhaobearxiong.bsky.social
,
@hnisonoff.bsky.social
, Ishan, Luke,
@jlistgarten.bsky.social
and
@davesavage.bsky.social
!
@savagecatsonly.bsky.social
add a skeleton here at some point
4 months ago
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