🆕🔥Medically Refractory Constipation With #ColonicHypercompliance: Comparison With #Megacolon and Healthy Colon‼️ 🎯Medically-refractory chronic constipation has colonic compliance similar to that of patients with megacolon👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM @mayoclinic.org

🆕🔥Brain changes underlying #IrritableBowelSyndrome symptom improvement in response to #Mindfulness‐Based Stress Reduction‼️ 🎯Improves #IBS symptoms by changing communication between brain regions at rest👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM #Gut-Brain 🧠Axis

🆕🔥#AdverseChildhoodExperiences due to #maltreatment are associated with #AbdominalPain intensity, poorer health-related quality of life, greater anxiety, and greater depressive symptoms, #Pediatric patients with #DGBI‼️ 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM #PEARLS

🆕🔥Colonic motility #mapping reveals a meal-induced #RectosigmoidBrake in healthy individuals that is disrupted, disorganized, or exaggerated following #surgery & in #MotilityDisorders‼️ #ileus #PseudoObstruction #FecalIncontinence 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥 #HeartRateVariability & #Sleep among Girls & Boys with #AbdominalPain‐related #DisordersofGutBrainInteraction‼️ 🎯Sleep-disordered breathing is associated with lower #HRV in both sexes #snoring #gasping 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM @drvantilburg.bsky.social 👏

🚨Fascinating Review🆕🔥 ⏩Intestinal α-Syn Oligomers as a Novel Pharmacological Target for #Parkinson'sDisease‼️ 🎯Novel insights into pathogenetic mechanisms👏 🎯Therapeutic feasibility of targeting gut-derived α-Syn oligomers💡 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Predominant Symptom in Gastroparesis: #Cohort #Treatments #Outcomes‼️ 🎯Most common predominant symptoms⏩#Nausea, #Vomiting & #AbdominalPain and PrS can change over time👏 🎯Abdominal pain associated with poorer QOL🔥 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM #GpCRC

🆕🔥#PercutaneousElectricalNerveFieldStimulation improves weight & other anthropometric outcomes in #Children & #Adolescents with #FunctionalDyspepsia who restrict their oral intake‼️ 🎯#PENFS can improve GI symptoms & #psychosocial outcomes #DGBIs👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Alternative Pathways of #Acetylcholine Release in Colon: Role of #HighAffinity Choline Transporters‼️ 🎯High-affinity choline transporters provide a novel pathway for acetylcholine release originating from neuronal sources👏 #ANMS #ESNM 👉 onlinelibrary.wiley.com/doi/10.1111/...

🆕🔥Adolescent normative intervals for #BodySurfaceGastricMapping‼️ 🎯BSGM normative reference intervals support test interpretation & allow specific phenotyping of gastric abnormalities & guide symptoms management👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Central & peripheral #Neuromodulators in #FD & #Gastroparesis: Symptom-Based #ClinicalReview‼️ 🎯A pragmatic, symptom-oriented & mechanism-based approach facilitate individualized treatment selection & optimize clinical outcomes 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Preserved #AntralContractions measured by #WirelessMotilityCapsule are associated with 🔽Response Rates to G-POEM in #IdiopathicGastroparesis patients‼️ 🎯Diminished antral contractions & gastric emptying delay are more likely to respond to G-POEM👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS#ESNM

🆕🔥 #Lactobacillus reuteri DSM 17938 improves #IntestinalMotility in 🐭 with #PostoperativeIleus by modulating #GutMicrobiota & #Macrophage‼️ 🎯L. reuteri DSM 17938 is a promising probiotic for the prevention of #POI👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥#WedgePillow vs. evening #ProtonPumpInhibitor for #NocturnalReflux symptoms‼️ 🎯Adding a wedge pillow was not inferior to evening PPI for nocturnal reflux symptoms ⏩Greater improvements in #sleep quality👏 👉https://onlinelibrary.wiley.com/doi/10.1111/nmo.70256 #ANMS #ESNM #GERD #PPI

🆕🔥Quantifying the Prevalence of #DisordersofGutBrainInteraction in #SystemicSclerosis‼️ 👉 onlinelibrary.wiley.com/doi/10.1111/... 🎯20% of patients with systemic sclerosis met diagnostic criteria for #IrritableBowelSyndrome or #FunctionalDyspepsia👏 #ANMS #ESNM

🆕🔥#MuscularisMacrophage-derived #ApoE is dispensable for maintaining #GutMotility 🐭‼️ 🎯Global ApoE deficiency delays gut transit & promotes inflammation, while macrophage-specific ApoE deletion does not impair motility #POI👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Combined utility of #CARS endoscopic score & #FLIP based on real‐time assessments‼️ 🎯Combination of CARS score ≥ 4 & reduced #EGJ opening on FLIP is highly predictive of an EGJ obstruction diagnosis #Achalasia #EGJOO👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Pilot validation study of🌱plant‐based & allergy‐friendly alternative for testing #GastricEmptying #HealthyParticipants‼️ 🎯Tested #vegan egg meal appears to be a suitable alternative to standard egg meal for patients who are not able to eat eggs 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Loss of #Myofilaments in gastrointestinal smooth muscle represents a novel pathological mechanism in MELAS-associated chronic intestinal Pseudo-obstruction #CIPO‼️ 🎯 #Mitochondrial dysfunction directly impairs smooth muscle contractile apparatus 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Distinct Phenotypes of #RectalProlapse #RP in Women‼️ 🎯#Defecation-only RP represents an early stage of disease #preserved #AnalSphincter function ⬇️#PelvicFloorLaxity👏 🎯Patients with #Spontaneous RP are older & have⬆️ fecal incontinence severity 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🆕🔥Accelerometric assessment of #Gastric Contractility using #Atmo Wireless Motility Capsule‼️ 🎯Atmo Capsule enables precise quantification of gastric contraction profiles, permitting differentiation of normal from pathological motor patterns👏 👉 onlinelibrary.wiley.com/doi/10.1111/... #NGM #ANMS #ESNM

🆕 #Neuroepithelial landscape of #Enterochromaffin cells varies across #GI location‼️ ✅EC cells rarely make contact with sensory nerves in upper gut but this frequency increases in distal colon👏 🎯 #Neuropods are not a preferential site of contact🔥 👉 onlinelibrary.wiley.com/doi/10.1111/... #ANMS #ESNM

🚨#NGMJournal Jan 2026 issue is live‼️🔥 ✅Dive Deep⏬ 🔗 onlinelibrary.wiley.com/toc/13652982... Editors: Daniel Keszthelyi Andrea Shin Nicolas Cenac, Neha Santucci Kristen Smith-Edwards Allison Malcolm David Reed Pierfrancesco Visaggi, Mohsin Butt Kristin Elfers Wilmarie Morales-Soto Rajan Singh 🙌

🚨#NGMJournal Jan 2026 issue is live‼️🔥 ✅Dive Deep⏬ 🔗 onlinelibrary.wiley.com/toc/13652982... Editors: Daniel Keszthelyi Andrea Shin Nicolas Cenac, Neha Santucci Kristen Smith-Edwards Allison Malcolm David Reed Pierfrancesco Visaggi, Mohsin Butt Kristin Elfers Wilmarie Morales-Soto Rajan Singh 🙌

📢 Remember those sleepless nights when you were kept awake from not knowing how the HSPG expression was in #ENS ganglia in #Hirschsprung 's disease?! 🤯 These days are over, as you can read all about it in our new paper @ngmjournal.bsky.social ! onlinelibrary.wiley.com/doi/10.1111/...

Thrilled to share our latest Clinical Review @ngmjournal.bsky.social🔥 Post-Coronavirus Disease #COVID-19 #IrritableBowelSyndrome: What We've Learned So Far‼️ 🦠Microbiota-gut–brain🧠communication 📢#GutBarrier matters most in Health & in post-COVID-19 DGBI 👉 onlinelibrary.wiley.com/doi/10.1111/nmo.70250

🚨Thrilled to welcome the new #EditorialTeam at #NGM led by our new Editor-in-Chief, Prof. Daniel Keszthelyi 🎉 🔊We look forward to great science & fascinating breakthroughs ahead in #Neurogastroenterology & #Motility #GutBrainScience #ANMS #ESNM

🚨We warmly welcome new editors to the #TeamNeuroGastro at @ngmjournal.bsky.social 🎉 Editors: Andrea Shin, Nicolas Cenac, Neha Santucci, Kristen Smith-Edwards, Allison Malcolm, David Reed, Pierfrancesco Visaggi, Mohsin Butt, Kristin Elfers, Wilmarie Morales, Rajan Singh🌟 #NeuroGastro #Motility

🚨Thrilled to welcome the new #EditorialTeam at #NGM led by our new Editor-in-Chief, Prof. Daniel Keszthelyi 🎉 🔊We look forward to great science & fascinating breakthroughs ahead in #Neurogastroenterology & #Motility #GutBrainScience #ANMS #ESNM