Eric Wang (@wanglab.bsky.social)

Thrilled to share our lab’s first paper, just out in Blood Cancer Discovery @theaacr.bsky.social! We uncovered an isoform-specific RUNX1C–BTG2 axis that drives chemoresistance in AML. aacrjournals.org/bloodcancerd...

loading . . .

An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance. Abstract. Aberrant levels or structures of RNA isoforms are a hallmark of many cancers, including acute myeloid leukemia (AML), yet its role in AML chemoresistance remains unclear. We conducted a pair... https://aacrjournals.org/bloodcancerdiscov/article/doi/10.1158/2643-3230.BCD-24-0327/763512/An-isoform-specific-RUNX1C-BTG2-axis-governs-AML?utm_source=twitter&utm_medium=social