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Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity This randomized clinical trial assesses the effect of metformin on knee pain among patients with symptomatic knee osteoarthritis and overweight or obesity. https://jamanetwork.com/journals/jama/fullarticle/2833338?guestAccessKey=477b3f91-844d-4017-bd0e-5eca517cee40&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamanetwork&utm_content=etoc&utm_term=052725