Very 🔥 science on DNA acessibility and TF footprinting from the @lucapinello.bsky.social lab!

4/ ACCESS-ATAC significantly improves TF binding site prediction, and in single-cell ACCESS-ATAC experiments, we resolve TF binding profiles at equal sensitivity to ATAC-seq with 2-3x fewer cells.

Our new paper out today: A bioprinted and scalable model of human tubulointerstitial kidney fibrosis. Led by Daphne Bouwens, Nazanin Kabgani and Jitske Jansen www.sciencedirect.com/science/arti...

We are recruiting a Tenure-track Assistant Professor "Machine Learning in the Life Sciences" at the Medical University of Vienna. We will nominate the top candidate for a € 1.8 million starting grant by a Viennese foundation. Deadline: Dec 31st. Details: medical-epigenomics.org/files/Tenure...

Have AI or ML skills? Have applied them to biological problems or high dimensional data problems? Want to get to a mechanistic understanding of animal behaviour and environmental influences on life? Want to live in Rome, work in an international, english speaking institute? Apply below!

We are happy to present SIGURD, a framework for single cell level analysis of somatic and mitochondrial variants from scRNA-seq data. This end-to-end framework allows genotyping, QC, functional analysis and data integration academic.oup.com/bib/article/... 1/5

And we get no break ... Saturday morning at home and I found another low dimensional embbeding (HATCH-MAP) in the floor.