Roberto Rossini
@robomics.bsky.social
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PostDoc at UiO developing computational tools for 3D genomics
reposted by
Roberto Rossini
Nezar Abdennur
3 months ago
We're excited to share our new preprint, "Joint decomposition of Hi-C maps reveals salient features of genome architecture across tissues and development", led by Thomas Reimonn.
www.biorxiv.org/content/10.1...
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Joint decomposition of Hi-C maps reveals salient features of genome architecture across tissues and development
The spatial organization of chromosomes in the nucleus is fundamental to cellular processes. Contact frequency maps from Hi-C and related chromosome conformation capture assays are increasingly availa...
https://www.biorxiv.org/content/10.1101/2025.08.07.669116v1
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reposted by
Roberto Rossini
Jonas Paulsen
4 months ago
🧬 New in Bioinformatics! We’re excited to share StripePy - a Python application for fast, robust detection of architectural stripes in Hi-C & Micro-C data. 🔗 Read the paper 👉
doi.org/10.1093/bioi...
#3DGenomics
#Bioinformatics
#HiC
#cool
#hic
@robomics.bsky.social
@rea191.bsky.social
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StripePy: fast and robust characterization of architectural stripes
AbstractMotivation. Architectural stripes in Hi-C and related data are crucial for gene regulation, development, and DNA repair. Despite their importance,
https://doi.org/10.1093/bioinformatics/btaf351
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