#mecfs Great PhD research by @aryback.bsky.social. Thank you, Audrey!

#Adaptogens in Long-Lasting Brain Fatigue: An Insight from Systems Biology and Network Pharmacology #Ashwagandha (Withania somnifera) and #ArcticRoot (Rhodiola rosea). www.mdpi.com/1424-8247/18... #brainfatigue

From Australia: Mapping the Complexity of ME/CFS: Evidence for Abnormal Energy Metabolism, Altered Immune Profile & Vascular Dysfunction papers.ssrn.com/sol3/papers.... "These findings imply decreased ATP generation & the presence of energy stress within the immune cell population" #MEcfs #CFS

Pleidooi van Piet Hoebeke @hoebekepiet.bsky.social en collega's voor vrijwaren wetenschappelijke vrijheid en integriteit

Happy 1-year anniversary today @bsky.app!

The Microplastic Concerns Elevate—To the Brain open.substack.com/pub/erictopo... #MNPs

Omega-3 fatty acids had a small protective effect of slowing biological aging (via multiple epigenetic clocks, Figure) nature.com/articles/s43... Exercise and Vit D were also assessed with some additive benefits but not significant on their own

"..majority of working age patients with PCS did not recover in the second year of their illness. Patterns of reported symptoms remained essentially similar, non-specific and dominated by fatigue, exercise intolerance and cognitive complaints..." #LongCovid journals.plos.org/plosmedicine...

I never thought a day would come when I would write a post this critical about the Cochrane Collaboration. But today was that day: absolutelymaybe.plos.org/2025/01/24/w... #mecfs

6) Hilda Bastian, leader of the IAG, has also published a blog laying out the history of the project and the implications for Cochrane: absolutelymaybe.plos.org/2025/01/24/w...

5) The Independent Advisory Group have now published an open letter to Cochrane: hbprojecttalk.wordpress.com/2025/01/24/i...

1) Good to see an article by Retraction Watch on the problematic Cochrane review on exercise therapy for ME/CFS.

Quote from the letter: "We express our dismay and concern at the rejection of our formal advice in 2024 to append an editorial note to the current version of the review stating that it is out of date and should not be used for clinical decision-making, as Cochrane has done for other reviews."

🔭 Supernova Remnant Cassiopeia A Image Credit: NASA, ESA, CSA, STScI; D. Milisavljevic (Purdue University), T. Temim (Princeton University), I. De Looze (University of Gent) apod.nasa.gov/apod/ap25011...

#Contaminants #FoodSafety #Metals #arsenic #nickel #cadmium #lead #mercury #chromiumVI #uranium

🆕 Draft scientific opinion on public health risks linked to #perchlorate in food. This re-evaluation takes into account new data and updated methodologies since the 2014 assessment. 🗣️ A public consultation is open for input until 11 Feb 2025. europa.eu/!ftpBhp #FoodSafety #Contaminants

A splashy new episode of our podcast 'Science on the Menu' is here 🌊 We’re exploring new uses of our oceans. How will new trade routes, sea mining and ocean aquaculture affect the safety of our food? Tune in to learn more → europa.eu/!B7WgBm #podcast #science

#cartoon #gaza #genocide (via www.lectrr.com)

1) There is some (cautious) excitement about this new ME/CFS paper that will soon be published. It replicated abnormalities in B-cells that were found by 2 earlier studies, namely an increase in Immunoglobulin Heavy Variable IGHV3-30.

'Scientists discover how viral infection triggers autoimmune disease' 'The Garvan team revealed that this is not the case – rather, the critical trigger is mutations in 'rogue clone' B cells' www.news-medical.net/news/2025011...

Glad to see this study protocol from Chris Armstong's group: Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME) pmc.ncbi.nlm.nih.gov/articles/PMC... #mecfs #adolescents

New US research Incidence & Prevalence of Post‑COVID‑19 Myalgic Encephalomyelitis:A Report from the Observational RECOVER‑Adult Study link.springer.com/article/10.1... "ME/CFS is a diagnosable sequela that develops at an increased rate following SARS-CoV-2 infection" #MEcfs #LongCovid

Taliban 'do not see women as human', says Malala Yousafzai www.bbc.com/news/article... #girlseducation

Something you don't see every day! Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins www.cell.com/cell/fulltex... open-access

1050 mg/day in #mecfs is an extremely high dose. Trying to intervene on the ETC should be done cautiously in hypersensitive ME/cfs patients. Moreover, high intake of some antioxidants may have pro-oxidative effects.

The ban on Bisphenol A/BPA in food contact materials in the EU ec.europa.eu/newsroom/san...