On behalf of the @istaart.bsky.social Design and Data Analytics PIA: New paper in Experimental Gerontology extends principal stratification to estimate the Survivor Average Causal Effect to model heterogeneity in treatment response in gerontologic trials. doi.org/10.1016/j.ex...

Causal Inference with Imperfect Data: Trial Emulation and Transportability Methods to Inform Dementia Prevention and Treatment Elizabeth Rose Mayeda, PhD UCLA UCSF Fein Memory and Aging Center Grand Rounds Monday, March 2, 10–11 a.m. PT register 👉

On behalf of @istaart.bsky.social #DaDA PIA: Join in San José at AAIC Neuroscience Next! 🧠 Feb 26, 2026 — Aging Research: Intro to Longitudinal Data Analysis Hands-on workshop with Dr. Ana W. Capuano on modeling change in cognition & function over time using real data. Registration now open!

Our new paper in Alzheimer’s & Dementia shows that automated item-level fluency features improve classification of semantic vs logopenic PPA. They outperform total scores & align with brain atrophy patterns—supporting scalable disease monitoring. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

On behalf of @istaart.bsky.social #DaDA PIA: Postdoctoral Associate opening in Pragmatic Dyadic Design. Seeking candidates with a PhD in biostatistics/quantitative methods, strong programming skills, and interest in pragmatic trials and AD/ADRD care. Apply here: postdocs.yale.edu/posts/2025-1...

On behalf of @istaart.bsky.social Design and Data Analytics #DaDA PIA: Are you interested in open science in #dementia research? Take the WYLDementia survey on data sharing in dementia research! Only 10 minutes, your insights can help shape more open & equitable science. forms.gle/GVuWAeHGmjaq...

Excited to share the launch of our new @istaart.bsky.social Cognition PIA SIG: Speech and Language Measures in Alzheimer’s Disease and Related Disorders, co-chaired with Alexandra König. Join our 1st meeting Jan 22, 2026 12:35pm CT (open to ISTAART members) Register: forms.monday.com/forms/9fd36c...

Don’t miss our free @istaart.bsky.social #DaDA PIA Year in Review webinar on Measurement Invariance & Harmonization across Cohorts, Jan 13 11:30am CT! Hear from speaker Dr. Sneha Mani & panelists Drs. Natalia Gomes Goncalves & Lars Lau Raket, moderated by yours truly. Register: alz.org/YearInReview

On behalf of @istaart.bsky.social Design and Data Analytics #DaDA PIA: New paper by Newsom et al. in Journal of Aging and Health explores how social support and strain predict multimorbidity trajectories. Support was linked to lower morbidity accumulation: journals.sagepub.com/doi/full/10....

On behalf of the @istaart.bsky.social Design and Data Analytics #DaDA PIA: 📣 An exciting full-time opportunity as a Postdoctoral Associate in Gerontologic Biostatistics at the Yale School of Medicine. Apply here: postdocs.yale.edu/posts/2025-1...

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: New paper by Nagel et al. in PLOS ONE uses sequence and cluster analysis to reveal distinct patterns of cardiometabolic disease accumulation and their link to later #dementia onset. Read more: doi.org/10.1371/jour...

On behalf of @istaart.bsky.social Design and Data Analytics PIA: We’ve compiled a new Resource Page on the ISTAART website highlighting key websites and tools shared during our #DaDA PIA Day at #AAIC2025. Check it out (PIA members only): urldefense.com/v3/__https:/... (File Categories>Resources)

On behalf of @istaart.bsky.social Design and Data Analytics PIA: New paper by Davis-Plourde et al. in Statistics in Medicine presenting 3 mixed model approaches for incorporating baseline outcomes in stepped wedge CRTs—valuable for trial design methodology. onlinelibrary.wiley.com/doi/10.1002/...

📣 Help shape our @istaart.bsky.social DaDA 2026 Year in Review webinar w/Dr. Sneha Mani on Measurement Invariance and Harmonization across Cohorts! What were standout papers, methods, or insights in 2025? What’s next in 2026? 📚 Suggest papers+trends: alz.surveymonkey.com/r/FSG8RXX ⏳ Deadline: Dec5

On behalf of the @istaart.bsky.social Design and Data Analytics #DaDA PIA: New work by Dr. Lars Lau Raket et al. in Brain maps time course of #Alzheimer’s disease biomarkers—showing journey from #amyloid β positivity to severe #dementia spans up to 25 years. Open access: doi.org/10.1093/brai...

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: Join for Webinar 3 in the ARISE 2025 series on Wed Oct 29, 12–1 PM CT! 🎓 Featuring early-career researchers at the intersection of aging, statistics, and data science Free and open to all – no registration required

Proud to share that I’ve received the official Notice of Award for my R01 from NIH National Institute on Aging: a 5yr $4.6M project to develop and validate speech-based tools for early Alzheimer’s detection. Grateful for my collaborators and the support—and spread the word: I’m hiring a postdoc!

Our new paper in Movement Disorders, led by Franco Ferrante, shows that digital fluency metrics from can predict and classify cognitive phenotypes in Parkinson’s disease, enabling scalable neuropsychological screenings. Read here: movementdisorders.onlinelibrary.wiley.com/doi/full/10....

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: We’re proud of our achievements and vibrant membership over the past year—and excited to keep building momentum in the year ahead!

On behalf of the @istaart.bsky.social Team: Join this week for one of two ISTAART All-Member Town Halls! 🌍 Learn about PIAs, meet leadership, and explore ways to get involved. 📅 Aug 26, 5–6 PM CDT 📅 Aug 27, 9–10 AM CDT 🔗 istaart.alz.org/home #ISTAART #AAIC

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: 🚨 Aug 27 = ARISE 2025 launch! 🚨 Join for cutting-edge work by early-career scientists in aging + data science—no registration needed. 🧠 Genetics, changepoints, missingness in EHRs. 📍 Free & open to all! #ARISE #AgingResearch

Our @istaart.bsky.social Design and Data Analytics #DaDA PIA committee and friends got together on Monday night at Toronto Island and had a blast! #AAIC25

Tomorrow (Tue) morning at #AAIC25: join us for a fantastic session on Speech and Language Methods for Detecting and Tracking Cognitive Decline 🧠🗣️ 📍 Room 107, North Building (Level 100) 🕘 9:00–10:30 AM 📅 Tuesday, July 29 🚶‍♀️ 8 min from Exhibit Hall Don’t miss it!

Happening now! #DaDA PIA session on design and analysis of non-pharmacological interventions in room Harbor C at #AAIC25 ; it's not too late to sneak in and take a seat!

Good morning Toronto! Ready for #AAIC25? It's Professional Interest Area #PIA day today at the Westin Harbour Castle, visit the Design and Data Analytics #DaDA booth for networking (12.30-2.30pm) and our session on design and analysis in trials at Harbour C (3.45-4.45pm)! See you there?

Our new paper in Epidemiology examines how timescale choice—study time vs. age—can influence estimates of exposure effects on memory change. Using data from 10 cohorts, we show how timescale decisions may shape findings and offer guidance for future cognitive aging research. doi.org/10.1097/EDE....

Happy to see the whole special section on the Journal of Neuropsychology (@bpsofficial.bsky.social) about the biomarker-based diagnosis of Alzheimer's disease (@alzassociation.bsky.social, @dementiaresearcher.bsky.social). Thanks to all authors! (Continued) 🧠 🧪 @jamiereillycog.bsky.social

On behalf of the @istaart.bsky.social Design and Data Analytics PIA #DaDA: New paper by Sun et al. presents a semiparametric joint model to examine how #biomarkers evolve with age and time to disease onset, applied to preclinical #Alzheimer’s. Read in Biometrics: doi.org/10.1093/biom...

On behalf of the @istaart.bsky.social Design and Data Analytics PIA #DaDA: Don’t miss Dr. Ana Capuano’s @anacapuano.bsky.social seminar “Modeling Change and Understanding Dementia Risk in Aging Research” at the University of Iowa on June 12 2025, 12–1 p.m. CT #Dementia #Aging

On behalf of the @istaart.bsky.social Design and Data Analytics (#DaDa) Professional Interest Area (#PIA):

On behalf of the @istaart.bsky.social Design and Data Analytics (#DaDa) Professional Interest Area (#PIA):

On behalf of @istaart.bsky.social Design and Data Analytics PIA: ARISE is calling for innovative data science methods in aging research! Students & young scientists, submit your work for a chance to present in our inaugural webinar series. Top projects win medals! Apply: forms.gle/EUrtnrFyNiuoj2Mf7

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: New study estimates how chronic conditions contribute to mortality across racial/ethnic groups. #Dementia showed the strongest link to death across groups. Read more: www.sciencedirect.com/science/arti... #ISTAART

Happy to share this commentary that @jamiereillycog.bsky.social and I wrote for our special section on the biomarker-based dx of Alzheimer's disease! doi.org/10.1111/jnp.... Featuring @ignaciomastro.bsky.social @smgrasso.bsky.social @jetmjvonk.bsky.social @timdaly.bsky.social

Our new paper in Neurology shows that automated speech analysis differentiates frontotemporal dementia subtypes using linguistic & acoustic features that align with known neuroanatomical patterns. This tool may aid early diagnosis & trial enrollment for TDP43 proteinopathies doi.org/10.1212/WNL....

On behalf of the @istaart.bsky.social Design and Data Analytics PIA #DaDA: New study by Lin et al. finds that at least 1 in 5 people with dementia & functional limitations receive no personal assistance, across several global regions. Read more in Nature Aging: doi.org/10.1038/s43587-025-00836-y

On behalf of @istaart.bsky.social Design and Data Analytics PIA: New study by Berge et al. examines the impact of the LIVE intervention on caregiver burden & care time in home-dwelling #dementia dyads. Read more in Alzheimer's & Dementia: alz-journals.onlinelibrary.wiley.com/doi/10.1002/... #DaDA

On behalf of @istaart.bsky.social Design and Data Analytics PIA: Learn valuable skills on March 24 10am CT when you join us for our webinar on how to carry out a meta-analysis in #dementia research with Mike Malek-Ahmadi, Heather Allore and Jet Vonk 🧠📊 Register today: alz-org.zoom.us/webinar/regi...

On behalf of @istaart.bsky.social Design and Data Analytics PIA: JUST OUT—Klee et al. examine multimorbidity contributors to dementia over time. A great international collaboration with researchers from Univ of Luxembourg, OHSU & Yale. Read more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

On behalf of @istaart.bsky.social Design & Data Analytics PIA: New paper by @anacapuano.bsky.social et al explores how #diabetes impacts #Alzheimer's pathology: phosphoprotein patterns in older adults' brains are different in those with diabetes alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

We need to shout from the rooftops how and why NIH funded health research is important, and what is accomplished with this work: www.bu.edu/sph/news/art... We're not just doing this because we secretly love reformatting our biosketches & spending weekends writing grants. #EpiSky

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: Applications are now open for the ΨMCA 2025 Conference on data harmonization & synthetic data in cognitive aging research. 📅 Aug 10–15 2025, Tahoe City, CA. Apply by Feb 28: psymca.org #CognitiveAging #DataScience

Honored to receive a UCSF Weill Catalyst Award (advancing translational research & entrepreneurship) for my project on speech-based biomarkers. This support & industry-advisor mentorship will help advance scalable non-invasive tools in #dementia research. innovation.ucsf.edu/venture/catalyst-program

On behalf of the @istaart.bsky.social Design and Data Analytics PIA: Join us on March 24 2:00 pm CT for The Basics of the Geriatric Emergency Care Applied Research Network with Dr. Ula Hwang & panelists. Plus, a Basics webinar on systematic reviews is coming soon! Register: alz.org/research-webinars

Invited commentary for J. Neuropsychology (thanks editors @davidebrunophd.bsky.social & @jamiereillycog.bsky.social). Enhancing cognitive tools' sensitivity could better align symptom detection with pathophysiological changes, bridging biological and clinical-biological perspectives on #Alzheimer’s

Another brilliant commentary for our (@jamiereillycog.bsky.social) series on the vices and virtues of the biological dx of #Alzheimer's disease 🧠🧪 (@bpsofficial.bsky.social). This one is by the amazing @jetmjvonk.bsky.social! bpspsychub.onlinelibrary.wiley.com/doi/10.1111/...

The great @jetmjvonk.bsky.social strikes again — this time at the deepest heart of the biomarker debate. a little more hyperbolic than is called for on my part

On Dec 17 I defended my second PhD at Utrecht University. This doctorate in Epidemiology complements my first in Speech-Language-Hearing Sciences. Grateful to my promotors & lifelong mentors, Mirjam Geerlings & Jennifer Manly, for their unwavering support. Thesis: pure.umcutrecht.nl/ws/portalfil...

Congrats to Drs. Jackie Torres & Elizabeth Rose Mayeda (and all the other people I do not know on this list but who are probably also amazing)! So proud to get to work with these phenoms working to #EndAlz. www.whitehouse.gov/ostp/news-up...