Karen Mohlke
@klmohlke.bsky.social
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reposted by
Karen Mohlke
The American Journal of Human Genetics
about 2 months ago
📣New from
@klmohlke.bsky.social
& co! 📄Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits
www.cell.com/ajhg/fulltex...
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Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits
To investigate the underlying mechanisms of complex traits, we performed an eQTL meta-analysis in skeletal muscle and identified 18,818 conditionally distinct signals for 12,283 genes. Colocalization ...
https://www.cell.com/ajhg/fulltext/S0002-9297(25)00359-3
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reposted by
Karen Mohlke
Sarah Brotman
10 months ago
I’m excited to share that this manuscript is now published in Nature Genetics! 🧪🧬 🖥️
www.nature.com/articles/s41...
The AdipoExpress data can be accessed here:
zenodo.org/records/1384...
An interactive browser of the colocalization results can be accessed here:
adipose.colocus.app
add a skeleton here at some point
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reposted by
Karen Mohlke
Sarah Brotman
about 2 years ago
I am excited to share our preprint describing a collaborative effort to identify conditionally distinct signals in the largest adipose eQTL dataset to date (AdipoExpress).
@kerrinsmall.bsky.social
@klmohlke.bsky.social
Laura Scott, and others 🧪🧬 🖥️
#GeneSky
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www.biorxiv.org/content/10.1...
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