Ever wonder how to figure out a molecule’s formula just from its mass? In today’s edition of Bioanalytical Bees, I break down how to ID compounds from scratch - no library, no MS2, just some mass spec magic. bioanalytics.substack.com/p/identifyin... #metabolomics #lcms

Important MOB talk coming up: A tutorial on depositing data to Metabolomics Workbench. I’ll admit: I only do it when a journal requires it, and I don’t usually go the extra mile with metadata. Hoping this seminar changes my ways! (Also, there’s free food 😊) www.moboston.com/about #metabolomics

Need a reference database for metabolite profiling? Training an ML model on chemical structures? Pubchem is the world’s largest chemical database, @pola.rs streaming engine lets you wrangle it on your laptop. bioanalytics.substack.com/p/processing... #cheminformatics #bioinformatics #Chemsky

What are internal standards and how exactly do we use them to correct for experimental hiccups? Shedding light on this important application of labelled metabolites. bioanalytics.substack.com/p/what-are-i...

In untargeted (metabol)omics, we don’t know what we’re looking for, so how do we optimize separation while maximizing metabolite coverage? Check out this post for some practical chromatography tips I wish I’d known earlier: bioanalytics.substack.com/p/optimizing... #metabolomics #lcms

Our paper showing that ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST is now published @cp-cellmetabolism.bsky.social Thanks to everyone involved! www.cell.com/cell-metabol...

A little late to Blusky but first things first: Join us at Metabolomics of Boston if you work on small molecule mass spectrometry! Come for the talks, stay for the people (& snacks, but maybe that's just me)