Excited and grateful to @upenn.edu Engineers for covering our lab! blog.seas.upenn.edu/penn-enginee...

Online today! Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity. www.nature.com/articles/s43...