CA’s 2022 MediCal expansion for undocumented 50+ led to more prescriptions for newer T2D meds. Prescriptions for undocumented patients matched documented levels by June 2023. #MediCalExpansion Read here ➡️ doi.org/10.2337/dc25-0787

Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies Read more ➡️ doi.org/10.2337/dc25-1401

Patient-specific CGM data optimization reduced MARD by up to 5.6% in patients, boosting accuracy and supporting safer clinical use in hospitals. Personalized algorithms may enable broader CGM adoption. Read here ➡️ doi.org/10.2337/dc25-1494

What you eat matters! New research shows proinflammatory and hyperinsulinemic diets increase the risk of type 2 diabetes and link to an unfavorable cardio-metabolic profile in women with prior GDM. Read here ➡️ doi.org/10.2337/dc25-1919

🚨 NEW special #podcast of Diabetes Core Update, where host Neil Skolnik explores the cutting-edge topic of automated insulin delivery for people with T2D. 👂 Listen now at: diabetesjournals.org/journals/pages/podcasts_aid_t2d This special edition of Diabetes Core Update is sponsored by Insulet.

Dual-Input Regulation of β-Cell Proliferation by ATF6α and Glucose via E2F1 Reads more ➡️ doi.org/10.2337/db25-0279

Also, check out the rest of the great articles in the @adapubs.bsky.social Diabtes Care Special Collection relating to the symposium on How to Fix a Broken Healthcare System at the 2025 @amdiabetesassn.bsky.social ADA Scientific Sessions #diabetes

Two phenotypic clustering approaches in youth-onset type 2 diabetes reveal novel reproducible type 2 diabetes clusters but offer no added prognostic value to simple clinical measures. Read here ➡️ doi.org/10.2337/dc25-1765

Successful Treatment of Diabetic Scleredema With Corticosteroids, Mycophenolate Mofetil, and UVA Therapy Read more ➡️ doi.org/10.2337/dc25-2272

Listening to hypoglycemia – machine learning detects hypoglycemia in people with diabetes using voice alone with high accuracy. Voice analysis may enable noninvasive hypoglycemia alerts. #Diabetes #AI Read here ➡️ doi.org/10.2337/dc25-1680

✨The Standards of Care in Diabetes—2026 is here!✨ 🔍 Discover key updates in diabetes technology, nutrition, pharmacotherapy, behavioral health, and more. 📖 Read now: diabetesjournals.org/care/issue/49/Supplement_1 #ADAStandards #DiabetesCare #Diabetes2026

🚨 New for December, a fresh episode of the #DiabetesBio #podcast! Featuring: ✨ Altering lipid localization & cellular composition ✨ HLA immune presentation ✨ Plus! metabolic Sweet Talk 🎙️Listen at: diabetesbio.libsyn.com 📚Read more: diabetesjournals.org/diabetes/issue/74/12

🚨 A new month, a new Care on Air! Where #podcast hosts Mike & Alice discuss the latest and greatest of Diabetes Care. 🎧 https://diabetescareonair.libsyn.com/site In this ep: ✨ T2D remission ✨ T2D and hypercortisolism ✨ and more! Read the full issue ➡️ diabetesjournals.org/care

Maternal Obesity Programs Glucose Intolerance in Pregnant Female Offspring Read more ➡️ doi.org/10.2337/db25-0603

A systematic review and meta-analysis of 81 studies shows that diabetes technologies positively impact treatment satisfaction, hypoglycemia fear and diabetes distress in adults with type 1 diabetes. Read more ➡️ doi.org/10.2337/dc25-1178

miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis Read more ➡️ doi.org/10.2337/db25-0295

NLP accurately extracted data from CGM documents stored in EHRs (99.87% Libre, 100% Dexcom). This enhances the efficiency of reusing CGM data for population-based research to improve diabetes care. Read more ➡️ doi.org/10.2337/dc25-1595

Cannabis isn’t risk-free for people with diabetes—it’s linked to higher DKA risk and blood sugar swings. Learn more and get tips for talking with your care team in this Diabetes Day by Day episode: https://bit.ly/4455IHL 🎧

Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score Read more ➡️ doi.org/10.2337/db25-0772

To improve population health and reduce health care spending, particularly for diabetes, the U.S. should improve income supports and work towards a public health care purchaser with monopsony power. Read more ➡️ doi.org/10.2337/dci25-0003

Gut Microbiota–Decanoic Acid–Interleukin-17A Axis Orchestrates Hyperglycemia-Induced Osteoporosis in Male Mice Read more ➡️ doi.org/10.2337/db25-0471

Tirzepatide Reduces Weight and Insulin Dose and Improves Body Composition in Type 1 Diabetes: A 12-Week, Phase 2 Randomised, Double-Blind, Placebo-Controlled Trial (TIRTLE1) Read more ➡️ doi.org/10.2337/dc25-2379

Lysyl Oxidase Promotes Actin-Dependent Neutrophil Activation and Cytotoxicity Toward Retinal Endothelial Cells in Diabetes Read more ➡️ doi.org/10.2337/db25-0541

🚨 For December, a brand new ep of #DiabetesCoreUpdate, the #podcast covering the most important articles in #diabetes. 🎧Listen at: https://bit.ly/DOC_Update Topics this month include: ✨Acute Pancreatitis & Incretin Medications ✨Predicting Heart Failure via Natriuretic Peptide Levels ✨and more!

Adaptive trial designs are reshaping research. In diabetes, only a handful exist — our scoping review highlights barriers and opportunities for broader Read more ➡️ doi.org/10.2337/dc25-1508

Flt3L-Derived Antigen-Presenting Cell Transfer in Neonatal NOD Mice Reduces the Incidence of Type 1 Diabetes Read more ➡️ doi.org/10.2337/db25-0055

Mendelian randomization and mediation analysis study shows that GLP-1RAs reduce the risk of myocardial infarction mainly via metabolic improvements (HbA1c, BMI, lipids, BP), with no direct effect. Read more ➡️ doi.org/10.2337/dc25-1822

⭐ 📖 Paper of the Month: Dec. Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells Walters et al. ➡️ doi.org/10.2337/db24... Articles are chosen 🗓️ monthly & 🆓 to read online #paperofthemonth #diabetes

Strategic Reduction of Hybrid Insulin Peptide Formation Significantly Delays Diabetes Onset in NOD Mice Read more ➡️ doi.org/10.2337/db25-0324

👀 The December 2025 issue of Diabetes Care is here, with the latest research on #diabetes management & care. 🔗 diabetesjournals.org/care/issue/48/12 Featuring: ✨ Hypercortisolism & T2D ✨ Exploratory analysis of the SYNERGY-NASH trial ✨ & more!

🚨The December 2025 issue of Diabetes has arrived! 🔗 diabetesjournals.org/diabetes/iss... Explore the latest research on #diabetes, including: ✨UCHL1 gene expression & adipocyte size ✨Hypoglycemia & the Million Veteran Program ✨& more!

GLP-1RA and DPP4i do not increase pancreatitis risk vs. SGLT2i, but both are linked to a small rise in biliary disease risk in real-world data from >1 million patients with type 2 diabetes. Read more ➡️ doi.org/10.2337/dc25-1840

🚨NEW special #podcast In ep 2 of our series on the Cardiovascular Outcome Trials (CVOTs), Dr. Neil Skolnik speaks with Darren McGuire, MD, about the aspects included in current trials and the results of these new methodologies. 👂Listen now: diabetesjournals.org/journals/pages/podcasts_cvot

β-Cell Mass in Individuals With and Without Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Read more ➡️ doi.org/10.2337/db25-0572

Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation Read more ➡️ doi.org/10.2337/db25-0215

Lower incidence of type 2 diabetes in people treated with verapamil vs. other calcium channel blockers – the benefits of verapamil in type 1 diabetes may extend to people at risk of type 2 diabetes. Read more ➡️ doi.org/10.2337/dc25-1440

📚 NEW: 2025-26 Guide to Diabetes Medications—complete reference for clinicians. All drug classes + comorbidity management. 📖 Chapters: doi.org/10.2337/978158040846 🛒 Print: shopdiabetes.org/collections/professional-books/products/2025-26-guide-to-medications-for-the-treatment-of-diabetes-mellitus

Children with type 1 diabetes and familial hypercholesterolemia (FH) are at extreme risk for cardiovascular disease. Despite checking lipids regularly, FH remains mostly unrecognized and untreated. Read more ➡️ doi.org/10.2337/dc25-1195

O-GlcNAcylation Stabilizes NEK7 to Drive Podocyte Pyroptosis in Diabetic Kidney Disease Read more ➡️ doi.org/10.2337/db25-0484

🚨The Fall issue of Diabetes Spectrum is now available. Explore the latest research on #diabetes, including: ✨Optimizing insulin delivery in pregnancy ✨System failure in #T1D ✨& more! 🔗http://diabetesjournals.org/spectrum/issue/38/4

BMI correlated with increased risk of islet autoantibodies (which typically precede symptomatic type 1 diabetes) but only after infancy. The association was dependent on HLA-DR-DQ haplogenotype. Read more ➡️ doi.org/10.2337/dc25-1198

Genotype-Phenotype Discrepancies in Family Members With a Novel Glucokinase Mutation: Insights Into GCK-MODY and Its Interplay With Insulin Resistance Read more ➡️ doi.org/10.2337/db24-1036

Congrats to Dr. Kevin Williams, recipient of The Obesity Society’s inaugural Xavier Pi-Sunyer Award at ObesityWeek® #OW2025! He co-hosts ADA’s podcast DiabetesBio and is AE for Diabetes. At UT Southwestern, his work advances understanding of brain regulation of metabolism and feeding.

African-Caribbean ethnicity is independently associated with higher risk of sight-threatening diabetic retinopathy in people with type 2 diabetes. Read more ➡️ doi.org/10.2337/dc25-0910

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function Read more ➡️ doi.org/10.2337/db25-0475

Meta-analysis showed multi-modal interventions using non-surgical approaches can safely increase T2D remission rates & improve A1C & quality of life. Tailored approaches are key. #T2DRemission Read more ➡️ doi.org/10.2337/dc25-0562

🚨 NEW special #podcast In this special episode of DCU's ongoing "What's Next" series, Neil Skolnik covers the latest updates on beta cell function and its role in the early detection of #T1D. 👂 Listen now at: diabetesjournals.org/journals/pag... This episode is sponsored by Sanofi.

🚨 New for November, a fresh episode of the #DiabetesBio #podcast! Featuring: ✨ Diabetes genetic clusters ✨ Weight loss with LEAP2 & Semaglutide ✨ Plus! Sweet Talk w Jens Juul Holst 🎙️Listen at: http://diabetesbio.libsyn.com 📚Read more: http://diabetesjournals.org/diabetes/issue/74/11

Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program Read more ➡️ doi.org/10.2337/db25-0304

🚨 A new Care on Air! Where #podcast hosts Mike and Alice discuss the latest and greatest of Diabetes Care. 🎧 diabetescareonair.libsyn.com/site In this ep: ✨ Undiagnosed G6PD deficiencies w @InesBarroso4 ✨ Upper-limb complications ✨ and more! Read the full issue ➡️ http://diabetesjournals.org/care