Check out the February issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

❤️ Early implantation of an internal loop recorder after cryptogenic stroke significantly improves the detection of silent paroxysmal atrial fibrillation compared to standard care. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Stroke #AF @ean.org #WileyNeuro

🧠 Deep Brain Stimulation outcomes in monogenic dystonia are highly dependent on genetic etiology. 📚 Read “Efficacy of Deep Brain Stimulation for the Treatment of Monogenic Dystonia Symptoms: A Systematic Review” by Indelicato et al. now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

In a nationwide Danish comparative effectiveness study of RRMS, no significant differences were found between Ocrelizumab and Natalizumab regarding relapse rates, disability progression (PIRA), or MRI activity. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro #MS

💪 Muscle MRI features can distinguish between distal myopathies (DMs) and distal hereditary motor neuropathies (dHMNs). A reticular pattern is an early feature of dHMNs while muscle islands are identified in advanced stages and in some forms of DMs, though not specific to neurogenic conditions.

😶‍🌫️ Patients with disorders of consciousness in focal brainstem injury show significant global reductions in brainstem-cortical white matter projections, particularly in the frontoparietal network. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Multimodal MRI serves as an accurate tool for detecting CNS damage in Hereditary Transthyretin Amyloidosis with polyneuropathy, highlighting the need for early monitoring beyond peripheral nerves. 📚 Read the recently published article: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

🧬 CES combined with HPO-based filtering is an effective strategy for suspected HSP, achieving a diagnostic yield of nearly 53%. While SPAST and SPG7 remain the most common mutations. 📚 Read the recently published article now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

📝 Call for Papers on Environmental Influences in Neurology Submission deadline: 31 August 2026 Find out more: www.eanpages.org/2026/01/22/c... @ean.org #WileyNeuro

Introducing the European Journal of Neurology Junior Reviewer Training Programme! The EAN, together with the European Journal of Neurology, is launching a brand new initiative designed to support the next generation of neurology researchers.

Check out the January issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

In a recently published article, #obesity was associated with diabetic peripheral #neuropathy (DPN), but not with painful DPN. Among males, obesity distribution did not differentially discriminate for DPN; however, in females, central obesity was the strongest discriminator of the condition

CSF-specific oligoclonal bands have a high sensitivity and specificity and a very high negative predictive value for diagnosing MS. However, the positive predictive value was lower in this cohort. 📚 Read the recently published article now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

SARS-CoV-2 infection was strongly associated with new-onset headache. Primary vaccination was associated with a small increased risk of headache during a low-transmission period, whereas booster offered protection on high-transmission 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

In a recently published clinical trial, tablet-assisted speech and language therapy showed potential benefits in patients with mild to moderate aphasia and less severe strokes in the acute setting. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #SLT #Aphasia @ean.org #WileyNeuro

A recently published article in the European Journal of Neurology argues that a decline in proximal CMAP amplitude may not indicate true motor conduction block. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #CIDP #EMG @ean.org #WileyNeuro

A recently published article on infectious #encephalitis showed that: * Immunocompromised status, status epilepticus, and GCS of < 8 during initial admission were significantly associated with poor neurological outcomes both at discharge and ≥ 6 months after infectious encephalitis onset.

GCA should be considered in IS/TIA patients ≥ 50 years with vertebrobasilar or multiterritorial involvement, or recurrent IS/TIA despite secondary prevention. 📚 Read the recently published article now: onlinelibrary.wiley.com/doi/10.1111/... #Arteritis #Stroke #TIA @ean.org #WileyNeuro

New-onset FND appears more likely after COVID-19 than other respiratory tract infections. Both the severity of the triggering illness and pre-existing individual vulnerability may contribute to the development of FND. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #FND @ean.org #WileyNeuro

Sleep abnormalities, bulbar dysfunction and movement disorders were most frequently reported in Anti-IgLON5 disease. 📚 Read “Anti-IgLON5 Disease: A Systematic Review and Meta-Analysis” by Groussauer & Barket et al. now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Check out the December issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

EEG background activity, assessed via individual alpha frequency, is sensitive to cognitive impairment related to antiseizure medications in people with epilepsy, demonstrated in both cross-sectional and longitudinal contexts.

A systematic review of 36 studies on Stiff-Person Syndrome highlights the paucity of data and heterogeneity in treatment responses, showing need for standardized assessment tools to evaluate therapies effectively. 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

A systematic review and meta-analysis of 52 studies shows that corneal nerve fiber length measured by corneal confocal microscopy has utility in the diagnosis of peripheral neuropathies. 📚 Read the article by Petropoulos et al. now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Actigraphic data reveals that patients with CIDP suffer from lowered sleep efficiency and increased nocturnal arousals, highlighting sleep disturbance as a significant non-sensorimotor symptom. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Long-term follow-up of the RINOMAX trial indicates that rituximab reduces disease activity and treatment burden in new-onset generalized myasthenia gravis compared to placebo. 📚 Read the article by Wu et al. now: onlinelibrary.wiley.com/doi/10.1111/... #MyastheniaGravis @ean.org #WileyNeuro

While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset. 📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

In a retrospective cohort of 134 patients and 46 controls who received iodine contrast, patients with acute ischemic stroke demonstrated increased CSF density. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Stroke @ean.org #WileyNeuro

Convincing evidence of true remyelination could only be found in preclinical studies investigating glatiramer acetate, teriflunomide, Fingolimod, Siponimod, Ponesimod, and alemtuzumab.

Olfactory dysfunction serves as a multifaceted clinical marker associated with convergent degeneration of nigrostriatal and limbic pathways, offering insights into PD phenotypic variance and its prognostic implications. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

Check out the November issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

⚡️ Steiner et al. report that CIDP burden extends beyond sensorimotor deficits. Motor and cognitive fatigue are clinically relevant and often under-recognized. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #CIDP @ean.org #WileyNeuro

🧪 Horst et al. find that in suspected infectious encephalitis, possible autoimmune encephalitis is uncommon and expanded anti-neuronal antibody panels add limited diagnostic yield. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Encephalitis @ean.org #WileyNeuro

🌱 Vitturi et al. report that environmental risks in the first 20 years are key for MS prevention based on a systematic review and meta-analysis. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #MS @ean.org #WileyNeuro

🧬 Pérez-Pérez and Olmedo-Saura et al. provide an update and roadmap to hereditary choreas. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Chorea @ean.org #WileyNeuro

🌙🧠 Zhou et al. suggest that glymphatic function measured with DTI-ALPS (Diffusion tensor image analysis along the perivascular space) links Cerebral Small Vessel Disease burden and sleep quality to cognitive decline. 📚 onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Sleep @ean.org #WileyNeuro

➖ Bjelica et al. show that in adult 5q-SMA on nusinersen treatment, CMAP amplitudes remained stable. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #SMA @ean.org #WileyNeuro

🦷 Camps-Plomer et al. report a significant association between periodontitis and migraine in Association Between Migraine and Periodontitis: A Systematic Review and Meta-Analysis. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Migraine @ean.org #WileyNeuro

🧫 Obara et al. conclude that NfL is the most validated ALS biomarker in blood and CSF. They warn that single marker use risks misclassification and recommend multimodal approaches. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #NfL #ALS @ean.org #WileyNeuro

💡 Shimada and Ishikawa et al. find that greater trapezius stiffness aligns with worse TTH severity. Weakness and heavy eyelid sensation may be useful clinical clues. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Headache @ean.org #WileyNeuro

Check out the October issue of European Journal of Neurology! 📚 Read now: onlinelibrary.wiley.com/toc/14681331... #EurJNeurol #Neurology #EJoN @ean.org #WileyNeuro

💡 Søborg et al. demonstrate that PACAP-38 levels are elevated across all cluster headache states, supporting PACAP as a therapeutic target while noting no clear correlation with CGRP. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #PACAP #ClusterHeadache @ean.org #WileyNeuro

🗣️ Hossain et al. show that shorter disease duration associates with behavioral dyscontrol, frontal lobe involvement, and higher 4-repeat tau burden in the locus coeruleus. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Apraxia @ean.org #WileyNeuro

🩺 Doneddu et al. demonstrate that incorporating additional electrophysiological parameters improves diagnostic sensitivity without compromising specificity, expanding the recognized spectrum of MMN abnormalities. 📚 onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Neuropathy @ean.org #WileyNeuro

⚡ Chemaly & Kuchenbuch et al. show that CBD reduces seizures and improves comorbidities, with strong 18-month retention supporting its efficacy and tolerability beyond approved indications. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Epilepsy @ean.org #WileyNeuro

❤️ Galea et al. find that LAAC is safe and feasible, with lower recurrent stroke rates than continued OAC alone, suggesting additive protection pending confirmation from randomized trials. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Stroke @ean.org #WileyNeuro

🧠 Caestecker et al. review in “The Locus Coeruleus–Noradrenergic System in the Healthy and Diseased Brain” how integrating anatomical, neurochemical, and functional data clarifies the LCNA system’s central role and therapeutic potential 📚 onlinelibrary.wiley.com/doi/10.1111/... @ean.org #WileyNeuro

💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #MECFS @ean.org #WileyNeuro

🧩 Marini et al. show in that the insular knife-cut sign on MRI strongly predicts HSVE and should raise immediate suspicion even when other tests are inconclusive. 📚 Read now: onlinelibrary.wiley.com/doi/10.1111/... #Neurology #Encephalitis @ean.org #WileyNeuro

🧪 Hegen et al. demonstrate that the κ-FLC index closely aligns with OCB, with discordant results mainly in the gray zone. A reflex testing approach using κ-FLC first and OCB for gray-zone cases appears reasonable. 📚 onlinelibrary.wiley.com/doi/full/10.... #Neuroimmunology @ean.org #WileyNeuro