Katy Patras
@katypatras.bsky.social
π€ 1347
π₯ 143
π 10
Assistant Professor, studies host-microbe interactions and women's health. Views are my own.
reposted by
Katy Patras
Drug Monkey
about 17 hours ago
This may be the most important paper ever published about NIH funded research.
www.science.org/doi/10.1126/...
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What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
https://www.science.org/doi/10.1126/science.aeb1564
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A critical message on the importance of federal funding in supporting global human health.
add a skeleton here at some point
about 2 months ago
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Excited to share a new preclinical model, human bladder organoids, to study UTI, novel therapies, and beyond! Developed with Dr. Sarah Blutt, the BCM Organoid Core, and
@tailor-labs.bsky.social
www.biorxiv.org/content/10.1...
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Human bladder organoids model urinary tract infection and bacteriophage therapy
Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), are among the most common antibiotic-resistant infections. Despite this, currently available preclinical UTI...
https://www.biorxiv.org/content/10.1101/2025.07.30.667685v1
about 2 months ago
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reposted by
Katy Patras
The Walker Lab at UTHealth
about 2 months ago
π£ Dont miss out! Registration just opened for the 6th CSAUTI Conference organized by
@globaluti.bsky.social
πApril 9-11th πNashville, TN
utiga.org/registration
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Urinary Tract Infection Global Alliance
No membership fees Join now!
https://utiga.org/registration
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Can phage treat infection AND vaccinate? We found that phage treatment protects mice against re-infection by the same pathogen. Out today in PNAS.
@tailor-labs.bsky.social
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2423286122
4 months ago
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reposted by
Katy Patras
α―IαTOα αIαET, α°αͺ
5 months ago
Bacteria! Weο»Ώ begin with only one! Bacteria! Two is what we then become! Bacteria! Each of us becomes two more! Bacteria! We are stronger than before! Bacteria! We keep growing at this rate! Bacteria! No longer shall we wait! Bacteria! The plan now unfolds! Bacteria! We will take over the world!
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Good to see
@tailor-labs.bsky.social
on here at last! Looking forward to more
#phage
in my feed.
5 months ago
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reposted by
Katy Patras
UTI Global Alliance
5 months ago
#UTIhour
is TOMORROW at 11am EDT/1500 UTC! Join us on Zoom to learn about host factors affecting
#UTI
, or check out the recording afterwards! Links to both are / will be available on our site at
UTIGA.org/upcoming
(zoom) or
UTIGA.org/past
(recording).
#UTIsky
#IDsky
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We found that women with RA have altered vaginal microbial and cytokine signatures, and higher levels of vaginal anti-citrullinated protein antibodies, compared to controls. This study reveals another important mucosal site affected by autoimmune disease.
www.medrxiv.org/content/10.1...
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A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis
Objective: The human microbiota is implicated in the development and progression of rheumatoid arthritis (RA). Given the increased RA burden in women, and well-known correlations between the vaginal m...
https://www.medrxiv.org/content/10.1101/2025.04.11.25325692v1
5 months ago
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reposted by
Katy Patras
The Walker Lab at UTHealth
6 months ago
Think UTIs are all about microbes? Think again.
#WeAreNotAlltheSame
βand your body plays a big role. Mark your calendars to find out whoβs at risk April 30th for
@globaluti.bsky.social
#UTIHour
hosted by
@katypatras.bsky.social
utiga.org/upcoming
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reposted by
Katy Patras
α―IαTOα αIαET, α°αͺ
6 months ago
The International Committee on Systematics of Prokaryotes (ICSP) reclassifies Group B ππ΅π³π¦π±π΅π°π€π°π€π€πΆπ΄ as its own genus: ππ’ππ’π€π΅π°π€π°π€π€πΆπ΄ ππ’π―π€π¦π§πͺπ¦ππ₯πͺπͺ I knew this was possible (e.g. ππ―π΅π¦π³π°π€π°π€π€πΆπ΄ used to be Group D ππ΅π³π¦π±π΅π°π€π°π€π€πΆπ΄) but still caught me by surprise Cool they are honoring Rebecca Lancefield!
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ICSP Defines New Firmicutes Genus: ππ’ππ’π€π΅π°π€π°π€π€πΆπ΄ ππ’π―π€π¦π§πͺπ¦ππ₯πͺπͺ
The International Committee on Systematics of Prokaryotes Renames Group B ππ΅π³π¦π±π΅π°π€π°π€π€πΆπ΄ as ππ’ππ’π€π΅π°π€π°π€π€πΆπ΄ ππ’π―π€π¦π§πͺπ¦ππ₯πͺπͺ
https://news.rr.nihalnavath.com/news/ICSP-Defines-New-Firmicutes-Genus--408261e9
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reposted by
Katy Patras
Jacqueline Kimmey
7 months ago
Happy Valentineβs Day from 5 kick ass microbiologists - who all made it to this weekβs zoom meeting for the first time in ages!
#women
#STEM
#faculty
#science
@katypatras.bsky.social
@laurainthelab1.bsky.social
@lindseyatutk.bsky.social
@alisoncoady.bsky.social
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reposted by
Katy Patras
Mike Tisza
8 months ago
We interrupt your regularly-scheduled chaos to bring you some cool microbiome science. π¦ π₯οΈ π§¬ "Longitudinal phageβbacteria dynamics in the early life gut microbiome" now out in Nature Microbiology. We wanted a way to measure bacteria and phage in metagenomes 1/
www.nature.com/articles/s41...
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Longitudinal phageβbacteria dynamics in the early life gut microbiome - Nature Microbiology
Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phageβbacteria dynamics over the first year of life.
https://www.nature.com/articles/s41564-024-01906-4
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After almost a decade (started while I was a postdoc with
@nizet.bsky.social
and finished by my own stellar students), happy to see this finally out. We found that Tamm-Horsfall protein, the most abundant protein in urine, enhanced NETosis to protect against UTI.
insight.jci.org/articles/vie...
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JCI Insight - Tamm-Horsfall protein augments neutrophil NETosis during urinary tract infection
https://insight.jci.org/articles/view/180024?utm_source=submission_site&utm_medium=email&utm_campaign=notice-of-publication
9 months ago
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reposted by
Katy Patras
Andreas BΓ€umler
9 months ago
Infection and Immunity has a call for papers on Womenβs Health and the Development of Microbiota in Childhood. For details see
journals.asm.org/journal/iai/...
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Womenβs Health and the Development of Microbiota in Childhood
Explore expert research on womenβs health and microbiota development in children
https://journals.asm.org/journal/iai/womens-health-microbiota
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Why is preterm birth risk doubled with maternal UTI? It depends on the immune response. We found distinct immune signatures in a UTI-associated preterm birth mouse model. In a human cohort from @AShea_Lab, urine cytokine levels could predict preterm birth.
www.biorxiv.org/content/10.1...
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Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection
Preterm birth is the leading cause of infant mortality resulting in over one million neonatal deaths annually. Maternal urinary tract infection (UTI) during pregnancy increases risk for preterm birth;...
https://www.biorxiv.org/content/10.1101/2024.10.22.619711v1
11 months ago
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