Brian Analikwu (@btanalikwu.bsky.social)

Telomeres stall DNA loop extrusion by condensin Analikwu et al. show that dense linear arrays of the telomeric protein Rap1 on DNA block DNA loop extrusion by condensin. Rap1-induced stalling depends on array length and protein density and leads to a local chromatin decompaction during anaphase, revealing how protein arrays can regulate SMC-driven genome organization. http://dlvr.it/TLhjFC