Today @yewonhan.bsky.social will give a flash talk about our metagenomic large-scale protein structure clustering and analysis at #RECOMB2025. Today (April 29) 1 p.m. at Global Lounge in “The Commons”

AFESM: a metagenomic guide through the protein structure universe! We clustered 821M structures (AFDB&ESMatlas) into 5.12M groups; revealing biome-specific groups, only 1 new fold even after AlphaFold2 re-prediction & many novel domain combos. 🧵 🌐 afesm.foldseek.com 📄 www.biorxiv.org/content/10.1...