Neurotransmission and Purinergic Signaling Lab (@neuropursignal.bsky.social)

Very happy to share with all of you our first publication on the human brain organoid model. Our findings point to a relevant role of purinergic signaling during the formation of the human cerebral cortex!!! 🧠 pubmed.ncbi.nlm.nih.gov/41320117/

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P2X purinergic receptors are required for correct cortical development in human brain organoids - PubMed The human neocortex represents a crucial evolutionary advance, the formation of which requires the tight and precise orchestration of both intracellular and extracellular signals. Structures grown in three-dimensional cultures, specifically human-induced pluripotent stem cells (hIPSCs)-derived cereb … https://pubmed.ncbi.nlm.nih.gov/41320117/