Jenny He
@jennyxinyi.bsky.social
📤 29
📥 61
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she/her Postdoc UCSF | BRAIN Initiative F32 Fellow | PhD UCSD rock climber, dog mom
pinned post!
I'm excited to share the first work from my postdoc in the von Zastrow lab! We address a fundamental question about neuromodulatory signaling: Can neurons tell the difference between multiple neuromodulatory inputs when they converge on only a few receptor pathways?
www.biorxiv.org/content/10.6...
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Temporal coding expands the bandwidth of GPCR-mediated neuromodulation
The advent of modern transcriptomic approaches has revealed a breadth of neuromodulatory G protein-coupled receptor (GPCR) co-expression far exceeding what was previously thought. This raises a fundam...
https://www.biorxiv.org/content/10.64898/2026.06.03.729927v1
16 days ago
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I'm excited to share the first work from my postdoc in the von Zastrow lab! We address a fundamental question about neuromodulatory signaling: Can neurons tell the difference between multiple neuromodulatory inputs when they converge on only a few receptor pathways?
www.biorxiv.org/content/10.6...
loading . . .
Temporal coding expands the bandwidth of GPCR-mediated neuromodulation
The advent of modern transcriptomic approaches has revealed a breadth of neuromodulatory G protein-coupled receptor (GPCR) co-expression far exceeding what was previously thought. This raises a fundam...
https://www.biorxiv.org/content/10.64898/2026.06.03.729927v1
16 days ago
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reposted by
Jenny He
Nicole Fisher
about 1 year ago
Excited to share my first paper from my postdoc! In this study, we demonstrate that the mu opioid receptor produces a second wave of G protein activity on endosomes in a manner that doesn’t require receptor internalization. Check it out!
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2420623122
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reposted by
Jenny He
Emily Blythe
over 1 year ago
New preprint! Here, we explore how endocytosis encodes receptor-specific cAMP/PKA signaling downstream of three endogenously coexpressed GPCRs.
www.biorxiv.org/content/10.1...
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Endocytosis sculpts distinct cAMP signal transduction by endogenously coexpressed GPCRs
Many G protein-coupled receptors (GPCRs) trigger a second phase of G protein-dependent signaling from internal membranes after agonist-induced endocytosis. However, individual GPCRs differ significant...
https://www.biorxiv.org/content/10.1101/2025.02.24.639927v1
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First post on 🦋! I had to honor to be featured in this article with Damon about our relationship with each other and with the outdoors! Happy Valentines ❤️
#Diversity
#diversifyoutdoors
www.melaninbasecamp.com/trip-reports...
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Outdoor Adventure Couple: Jenny and Damon — Melanin Base Camp
Jenny recalled. “We spent so much time together in the car, talking for hours. It was a great way to connect.” Damon agreed, adding, “Outdoor trips gave us a chance to bond in ways that everyday life ...
https://www.melaninbasecamp.com/trip-reports/2025/2/5/outdoor-adventure-couple-jenny-damon
over 1 year ago
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reposted by
Jenny He
Ashley Juavinett, PhD
over 1 year ago
In California NIH FUNDING: $5.31 B JOBS SUPPORTED: 55,949 ECONOMIC ACTIVITY SUPPORTED: $13.55 B KEEP IT GOING
add a skeleton here at some point
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