Julia Vorhauser
@juliavorhauser.bsky.social
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Postdoc in the Wredenberg lab at Karolinska Institute. Interested in redox biology and metabolism :D
reposted by
Julia Vorhauser
WredenbergLab
about 1 month ago
We are hiring! Come and join us in Stockholm to study mitochondrial metabolism.
ki.varbi.com/what:job/job...
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Postdoctoral researcher in mitochondrial biology (scholarship)
Do you want to contribute to improving human health? The Division of Molecular Metabolism at Karolinska Institutet is located in the newly built Biomedicum at the Solna campus. The division offers a h
https://ki.varbi.com/what:job/jobID:889199/
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reposted by
Julia Vorhauser
H.P.
5 months ago
„Man kann sich mit dem Nationalsozialismus geistig nicht auseinander-setzen, weil er ungeistig ist." Alexander Schmorell, Mitbegründer der Widerstandsgruppe Weiße Rose, Verfasser bekannter Flugblätter der Gruppe, wurde am 16 September 1917 geboren. Guten Morgen 
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reposted by
Julia Vorhauser
The Institute of Cancer Research
6 months ago
The findings highlight a new way of thinking about how cell growth is controlled – one that could eventually be harnessed to improve cancer treatment ⤵️
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Subtle chemical tweak helps determine whether cells grow, potentially affecting cancer risk
Subtle chemical tweak helps determine whether cells grow, potentially affecting cancer risk
https://www.icr.ac.uk/about-us/icr-news/detail/subtle-chemical-tweak-helps-determine-whether-cells-grow--potentially-affecting-cancer-risk
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I am very happy to share that my PhD work in the Mansfeld lab (
www.mansfeldlab.com
) was published yesterday! 🎉 In this study, we characterized a novel redox switch on p21 that regulates proliferation:
www.cell.com/molecular-ce...
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
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A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision
ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase contro...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(25)00646-X
6 months ago
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reposted by
Julia Vorhauser
MRC Laboratory of Medical Sciences
about 1 year ago
New research from Steve Cutty and
@alexisbarr.bsky.social
published in the British Journal of Cancer shows the protein p21 promotes survival in lung cancer cells strengthening the rationale for targeting p21 as a cancer treatment. This work was also funded by
@cancerresearchuk.org
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Blocking the cell cycle inhibitor p21 prevents regrowth in lung cancer cells
Blocking the activity of a protein called p21 stops lung cancer cells entering a ‘sleep-like’ state that allows them to survive chemotherapy. Blocking p21 causes more cancer cells to die and reduces t...
https://lms.mrc.ac.uk/blocking-the-cell-cycle-inhibitor-p21-prevents-regrowth-in-lung-cancer-cells/
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