@sandipbasak.bsky.social
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pinned post!
We are excited to share our latest work on GLIC published in
@pnas.org
, where we developed a
#cryoEM
data processing strategy that allowed us to isolate and reconstruct multiple asymmetric states, revealing detailed insights into the channel’s activation mechanism.
tinyurl.com/mwtb4rpj
loading . . .
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM | PNAS
Pentameric ligand-gated ion channels (pLGICs) are vital neurotransmitter receptors that are key therapeutic targets for neurological disorders. Alt...
https://tinyurl.com/mwtb4rpj
3 months ago
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A detailed tutorial has now been added to the GitHub page.
add a skeleton here at some point
2 months ago
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reposted by
Sjors Scheres
3 months ago
We are looking for a computational postdoc to work with us on new optimisation algorithms to make
#RELION
even better. Join our bubbly team at the
@mrclmb.bsky.social
in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
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Quick Check Needed
https://mrc.tal.net/vx/appcentre-ext/brand-3/spa-1/candidate/so/pm/4/pl/1/opp/2737-Postdoctoral-Scientist-Structural-Studies-Dr-Sjors-Scheres-LMB-2737/en-GB
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reposted by
Nikhil Bharambe
3 months ago
We're thrilled to publish our latest research on the GLIC ion channel in PNAS! We developed a powerful new
#cryoEM
data processing strategy that resolves asymmetry. 📄 Read the full paper:
tinyurl.com/mustun6t
🛠️ Scripts:
tinyurl.com/2n3yk29r
Stay tuned for a full tutorial soon!
#PNAS
#RELION
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reposted by
Phil Biggin
3 months ago
Pleasure to be part of this work
www.pnas.org/doi/10.1073/...
with Sandip Basak at NTU where we show asymmetric gating in GLIC!
loading . . .
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM | PNAS
Pentameric ligand-gated ion channels (pLGICs) are vital neurotransmitter receptors that are key therapeutic targets for neurological disorders. Alt...
https://www.pnas.org/doi/10.1073/pnas.2512811122
0
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We are excited to share our latest work on GLIC published in
@pnas.org
, where we developed a
#cryoEM
data processing strategy that allowed us to isolate and reconstruct multiple asymmetric states, revealing detailed insights into the channel’s activation mechanism.
tinyurl.com/mwtb4rpj
loading . . .
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM | PNAS
Pentameric ligand-gated ion channels (pLGICs) are vital neurotransmitter receptors that are key therapeutic targets for neurological disorders. Alt...
https://tinyurl.com/mwtb4rpj
3 months ago
1
16
6
reposted by
Guillaume Thibault
5 months ago
📣 Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up package. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more!
#FacultyJobs
#TenureTrack
Register HERE:
lnkd.in/gSy5qpA7
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reposted by
Guillaume Thibault
9 months ago
Visiting Cambridge/Oxford/London w/
@sim0nredfern.bsky.social
to connect w/ potential applicants for Nanyang Assistant Professorship (NAP) @ NTU SG. NAP offers tenure-track position w/ up to S$2.75M start-up. Join us and register at one of our recruitment events 👇
www.ntu.edu.sg/science/rese...
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