@sanjanakmani.bsky.social
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pinned post!
Our latest work in
@jacs.acspublications.org
! Artificial system that can sense, grow, and adapt—just like cells! Our
#droplets
form directional filopodia in response to chemical cues- a step toward life-like materials.
#SoftMatter
#MatterToLife
đź”—https://pubs.acs.org/doi/10.1021/jacs.5c11719
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about 2 months ago
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Thrilled to receive the Poster Award at Materials Day 2025 organized by PennStateMRI! We explore how interfacial phenomena drive dynamic
#emulsions
and life-like behavior in soft
#materials
. More @
sites.psu.edu/sengroup/
! Grateful to
@ayusmansen.bsky.social
@pennstatechemistry.bsky.social
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The Sen Group – Active autonomous systems; synthetic nano and micromotors; micropumps; nanotechnology, systems chemistry research at Penn State
Active autonomous systems; synthetic nano and micromotors; micropumps; nanotechnology, systems chemistry research at Penn State
https://sites.psu.edu/sengroup/
about 1 month ago
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reposted by
Ayusman Sen
about 2 months ago
Spiral patterns form by simply dropping protein solutions on to denser sugar solutions, showing reaction-diffusion pattern formation can be replicated by replacing the reaction-induced inhomogeneous solute distribution by evaporation-induced inhomogeneity:
rdcu.be/eMUyR
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Pattern formation in isothermal miscible protein-sugar systems driven by Marangoni effects and evaporation
Communications Physics - Pattern formation in miscible fluid systems is typically driven by reaction-diffusion processes or thermal gradients. This study demonstrates pattern formation in an...
https://rdcu.be/eMUyR
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reposted by
Ayusman Sen
about 2 months ago
Our latest: Like bacteria, oil-in-water emulsions sense specific amino acids, sending out finger-like projections towards or away from the source! Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation. Great work by
@sanjanakmani.bsky.social
pubs.acs.org/doi/full/10....
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Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation
Cells are complex chemical systems capable of sensing and responding to environmental cues by dynamically reshaping themselves, e.g., by forming arm-like protrusions such as filopodia. Recapitulating cellular behavior in artificial systems is a long-standing goal in understanding the matter-to-life transition and designing responsive soft materials. Here, we use oil-in-water emulsions that mimic cellular environmental sensing and form directional arm-like filopodia in response to external chemical cues. Our work analyzes the step-by-step process involved in the formation of artificial filopodia, and we engineer ways to direct filopodia growth through different chemical gradients. The process is driven by asymmetric surfactant partitioning across the oil–water interface, followed by ordering at the interface to form lamellar structures, which are projected out as filopodia. We observe filopodia growing away from the source of kosmotropic anions and toward the source of chaotropic anions from the Hofmeister series. Significantly, these systems also respond to amino acid gradients, similar to cells: tryptophan gradients favor growth toward the source, while lysine and arginine gradients cause growth away from the amino acid source. Our findings open new avenues for fabricating life-like materials that sense and grow in response to external signals.
https://pubs.acs.org/doi/full/10.1021/jacs.5c11719
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Deeply grateful to my advisor
@ayusmansen.bsky.social
for his invaluable guidance, and to Dr. Lauren Zarzar, and all the amazing collaborators who made this work possible!
@pennstatechemistry.bsky.social
@pennstatescience.bsky.social
add a skeleton here at some point
about 2 months ago
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Our latest work in
@jacs.acspublications.org
! Artificial system that can sense, grow, and adapt—just like cells! Our
#droplets
form directional filopodia in response to chemical cues- a step toward life-like materials.
#SoftMatter
#MatterToLife
đź”—https://pubs.acs.org/doi/10.1021/jacs.5c11719
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about 2 months ago
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reposted by
Ayusman Sen
4 months ago
Fellow motorists, follow the roadmap for an exciting journey! Many thanks to Samuel Sanchez and others for their insights:
add a skeleton here at some point
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reposted by
Ayusman Sen
6 months ago
We are on our way to designing intelligent communicating systems involving particle populations that carry out different tasks. Non-reciprocal chemotactic movement in enzyme cascade under flow-free conditions: Cell Reports Physical Science
www.cell.com/cell-reports...
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Non-reciprocal chemotactic movement in enzyme cascade under flow-free conditions
Sapre et al. showcase a hydrogel-based microfluidic device that creates chemical gradients under flow-free conditions for studying enzyme-powered chemotaxis. The setup allows long-term observation of ...
https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864%2825%2900265-6
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reposted by
Ayusman Sen
8 months ago
"Life of a Droplet: A Non-Equilibrium Drama." Congratulations
@sanjanakmani.bsky.social
@pennstatechemistry.bsky.social
for winning first prize in Visual Appeal at the Penn State Materials Visualization Competition.
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Thrilled to have won 1st prize in Visual Appeal for "Life of a Droplet: A Non-Equilibrium Drama" at the Materials Visualization Competition. Grateful to
@ayusmansen.bsky.social
@pennstatechemistry.bsky.social
and PennStateMatSE.
sites.psu.edu/mvcs/17-winn...
#MaterialScience
#SciArt
8 months ago
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