Zachary McCaw
@zmccaw.bsky.social
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Biostatistician and machine learning scientist
reposted by
Zachary McCaw
Tom Soare
4 months ago
We’re excited to share a new article from
@insitro.bsky.social
(first author
@zmccaw.bsky.social
) in
@ajhgnews.bsky.social
, introducing a summary-statistic-based implementation of the COding-variant Allelic Series Test, COAST-SS:
www.sciencedirect.com/science/arti...
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A scalable framework for identifying allelic series from summary statistics
Genes where a dose-response relationship exists between functionality and phenotypic impact are appealing therapeutic targets, as the effects of pharm…
https://www.sciencedirect.com/science/article/pii/S0002929725003684
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