@h-sokol.bsky.social
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New link between the gut Microbiome, bile acids and Osteoarthritis : Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling | Science
www.science.org/doi/10.1126/...
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Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling
Whether a gut-joint axis exists to regulate osteoarthritis is unknown. In two independent cohorts, we identified altered microbial bile acid metabolism with reduced glycoursodeoxycholic acid (GUDCA) i...
https://www.science.org/doi/10.1126/science.adt0548
8 months ago
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reposted by
Nathalie Rolhion
9 months ago
Ravie d'avoir présenté nos travaux aux
#JFHOD2025
. Un grand merci à Zhan qui a mené ce projet de collaboration avec Biocodex ainsi qu'à Loic, Laura, Rand,
@jeremielefevre.bsky.social
et
@h-sokol.bsky.social
add a skeleton here at some point
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Intestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood - Gastroenterology
www.gastrojournal.org/article/S001...
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Intestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood
Increased serotonin in the gut epithelium is anxiolytic and antidepressive which is mediated through vagal signaling. Maternal selective serotonin reuptake inhibitor exposure is associated with a risk...
https://www.gastrojournal.org/article/S0016-5085%2824%2905751-2/fulltext
9 months ago
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www.sciencedirect.com/science/arti...
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Mucosal macrophages govern intestinal regeneration in response to injury.
Cancer patients treated with radiotherapy in the abdominal and pelvic cavity develop radiation-induced enteritis, a condition that impairs their quali…
https://www.sciencedirect.com/science/article/pii/S0016508525004652
9 months ago
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www.cghjournal.org/article/S154...
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Risk of age-related and disease-related complications and mortality in elderly-onset IBD - a population-based study
In this nationwide cohort from Israel (Epi-IIRN), we aimed to characterize risks for age-related complications, mortality and IBD-related surgeries in patients with elderly-onset inflammatory bowel di...
https://www.cghjournal.org/article/S1542-3565(25)00195-8/abstract?rss=yes
9 months ago
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Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease: Cell
www.cell.com/cell/fulltex...
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Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease
A metagenome-informed metaproteomics approach unravels the interplay between the host, gut microbiome, and diet in animal models as well as in human cohorts and identifies disease biomarkers of dysbio...
https://www.cell.com/cell/fulltext/S0092-8674%2824%2901429-6
11 months ago
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