Bhavya N P
@npbhavya.bsky.social
📤 378
📥 272
📝 17
Bioinformatician
It’s official! I am a doctor 🎓
add a skeleton here at some point
about 2 months ago
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Bhavya N P
Vijini Mallawaarachchi
4 months ago
Excited to share our latest preprint on agtools, an open-source Python framework for analysing and manipulating assembly graphs. (1/n)
www.biorxiv.org/content/10.1...
#Bioinformatics
#genomics
#assembly
#assemblygraphs
#software
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agtools: a software framework to manipulate assembly graphs
Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap information, facilitating the assembler to construct longer genomic f...
https://www.biorxiv.org/content/10.1101/2025.09.14.676178v1
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reposted by
Bhavya N P
George Bouras
5 months ago
Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation
#phagesky
1/n
www.biorxiv.org/content/10.1...
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Protein Structure Informed Bacteriophage Genome Annotation with Phold
Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents. Here we introduce Phold, an annotation framework utilis...
https://www.biorxiv.org/content/10.1101/2025.08.05.668817v1
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Bhavya N P
Stevie Ped
5 months ago
For any hoping to submit workshop proposals for ABACBS25/BiocAsia, EOIs close today. We understand how busy everyone is, so if your EOI is a day or so late, it'll still be considered. We've already had some fantastic proposals too, so it looks like being a really beneficial couple of days. 🧬 🖥️
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Workshops 2025
https://www.abacbs.org/abacbs-2025-workshops
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Bhavya N P
Rob Edwards
5 months ago
🌟 Exciting news! We’re launching three fully-funded postdoc positions for "New Horizons for Synthetic Phages” Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide. 👇 Read on for details!
#Phage
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Bhavya N P
Susie Grigson
5 months ago
🚨 New preprint 🚨 My phage annotation tool, Phynteny, finally has a preprint and a brand new version powered by a cool AI transformer architecture and protein language models!
#phagesky
www.biorxiv.org/content/10.1...
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Synteny-aware functional annotation of bacteriophage genomes with Phynteny
Accurate genome annotation is fundamental to decoding viral diversity and understanding bacteriophage biology; yet, the majority of bacteriophage genes remain functionally uncharacterised. Bacteriopha...
https://www.biorxiv.org/content/10.1101/2025.07.28.667340v1
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Bhavya N P
Rob Edwards
5 months ago
Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins Structural predictions to improve
#phage
genome annotation!
@hannelorelongin.bsky.social
@gbouras13.bsky.social
y.social
@susiegriggo.bsky.social
@veravannoort.bsky.social
www.biorxiv.org/content/10.1...
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Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins
Phages, the viruses of bacteria, harbor an incredibly diverse repertoire of proteins capable of manipulating their bacterial hosts, inspiring many medical and biotechnological applications. However, t...
https://www.biorxiv.org/content/10.1101/2025.07.17.665397v1
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Bhavya N P
6 months ago
🚨 Reminder: Key
#ABACBS2025
deadlines are fast approaching in the next few weeks! 🚨 📝 Abstract submissions 🎤 EOI to host a Workshop 🏆 Award nominations All now open! Full details + dates here 👉
www.abacbs.org/abacbs2025
#Bioinformatics
#ABACBS
#COMBINE2025
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ABACBS 2025 Conference
Adelaide, South Australia. Nov. 24-
https://www.abacbs.org/abacbs2025
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Bhavya N P
Liza Kretzschmar
6 months ago
The 2025 South Australian Internship in Indigenous Genomics is open 🎉 EOI for Indigenous Australian students, researchers & professionals for a 12- week paid internship 👇
sahmri.org.au/careers-and-...
#GenomicsEquality
#IndigenizeScience
#IndigenousGenomics
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Expressions of Interest Paid Internship in Indigenous Genomics
https://sahmri.org.au/careers-and-study/working-at-sahmri/vacancies/expressions-of-interest-paid-internship-in-indigenous-genomics
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Bhavya N P
Rob Edwards
6 months ago
PhD opportunities at
@flindersuniversity.bsky.social
in Adelaide, Australia's most liveable city, to study genetics in
#phage
We will also have genetics
#postdoc
positions too!
#microsky
#phagesky
www.linkedin.com/pulse/phd-pr...
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PhD Project: Discovering Novel Mechanisms of Phage Genome Evolution
We are looking for an awesome PhD student to join our research team to investigate how bacteriophages (phages) generate targeted mutations that enable them to evolve and infect new bacterial hosts. Yo...
https://www.linkedin.com/pulse/phd-project-discovering-novel-mechanisms-phage-genome-rob-edwards-xojjc
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reposted by
Bhavya N P
Rob Edwards
6 months ago
We made structural predictions of representatives of each
#PHROG
from
#phage
genomes, and put the whole lot online. You can browse through montages or go to your favourite phrog directly and download its PDB. 💻🧬
#phagesky
linsalrob.github.io/PHROG_struct...
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PHROG Structure Gallery
https://linsalrob.github.io/PHROG_structures/
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Bhavya N P
6 months ago
Finally joined Bluesky! Follow along to stay connected with ABACBS. Keep an eye out in the coming days, we’ll be releasing more details for 2025 conference, including opening abstract submissions and announcing invited speakers!
www.abacbs.org/abacbs2025
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ABACBS 2025 Conference
Adelaide, South Australia. Nov. 24-
https://www.abacbs.org/abacbs2025
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reposted by
Bhavya N P
Feargal Ryan
9 months ago
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it
#microbiome
#science
#immunology
www.nature.com/articles/s41...
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Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
https://www.nature.com/articles/s41586-025-08796-4
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Bhavya N P
Pawsey Supercomputing Research Centre
9 months ago
🎥 Supercomputing vs Superbugs 💻🦠 Antibiotic resistance is a growing threat, but Sphae—a genomic toolkit developed with help from Pawsey Supercomputing—helps scientists discover new bacteriophage therapies. Learn how this powerful tool is transforming health:
hubs.ly/Q03c_VC70
#PhageTherapy
#Setonix
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Excited to see our tool, Sphae, gaining attention!
#PhageTherapy
#Bioinformatics
#Sphae
#phagesky
add a skeleton here at some point
9 months ago
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reposted by
Bhavya N P
Rob Edwards
10 months ago
Check out this list of awesome
#virome
tools and be sure to add yours!
github.com/shandley/awe...
#phagesky
#microsky
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GitHub - shandley/awesome-virome: A listing of software, tools and databases useful for virome analysis
A listing of software, tools and databases useful for virome analysis - shandley/awesome-virome
https://github.com/shandley/awesome-virome
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reposted by
Bhavya N P
Rob Edwards
11 months ago
Helping viruses deliver a knockout blow to killer bacterial infections! Great work by
@npbhavya.bsky.social
phys.org/news/2025-02...
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Helping viruses deliver a knockout blow to killer bacterial infections
In the face of rising concerns about antibiotic resistant infections, an international group of microbial experts have launched a powerful and flexible free online genomic toolkit for more rapid devel...
https://phys.org/news/2025-02-viruses-knockout-killer-bacterial-infections.html
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New paper out! I'm excited to share our latest work in Bioinformatics Advances! We've developed Sphae, a bioinformatics pipeline to evaluate phage therapeutic potential.
doi.org/10.1093/bioa...
Try it here:
github.com/linsalrob/sp...
#PhageTherapy
#AMR
#Bioinformatics
#phagesky
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GitHub - linsalrob/sphae: Phage annotations and predictions. A spae is a prediction or foretelling. We'll foretell you what your phage is doing!
Phage annotations and predictions. A spae is a prediction or foretelling. We'll foretell you what your phage is doing! - linsalrob/sphae
https://github.com/linsalrob/sphae
12 months ago
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reposted by
Bhavya N P
Mike Blazanin
about 1 year ago
Check out Nora's amazing postdoc project on phage species coexistence!
add a skeleton here at some point
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reposted by
Bhavya N P
Rob Edwards
about 1 year ago
Trying to purify and sequence
#phage
for phage therapy? Try
#sphae
a new approach to identify if your phage could be useful for treatment
#phagesky
add a skeleton here at some point
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reposted by
Bhavya N P
Rob Edwards
about 1 year ago
Honoured to have been voted as President-elect of the International Society for the Viruses of Microbes (ISVM) and excited to work with the Executive Board over the next few years
#phagesky
phagesociety.org
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ISVM – International Society for Viruses of Microorganisms
https://phagesociety.org/
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The final talk at the
#combine24
protein structure session on predicting the effect of mutations on protein structures by Emily Zhou
about 1 year ago
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@gbouras13.bsky.social
presenting his tool PHOLD to use protein structure information for assigning a function to unknown proteins
#COMBINE24
about 1 year ago
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@susiegriggo.bsky.social
introducing her new tool PHLEGM to build multimeter of phage proteins
#COMBINE24
about 1 year ago
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reposted by
Bhavya N P
George Bouras
about 2 years ago
Here is Hybracter, our tool for generating automated hybrid & long-read-only bacterial genome assemblies. Github:
github.com/gbouras13/hy...
Docs:
hybracter.readthedocs.io/en/latest/
Preprint:
www.biorxiv.org/content/10.1...
@npbhavya.bsky.social
@linsalrob.bsky.social
#Microsky
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🎉 Excited to introduce
#SPHAE
! Our new workflow for phage genome analysis generates complete genomes, annotations, & comprehensive summaries of genome features. Check it out:
github.com/linsalrob/sphae
#phagesky
@linsalrob.bsky.social
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GitHub - linsalrob/sphae: NEW!!! Phage annotations and predictions. A spae is a prediction or forete...
NEW!!! Phage annotations and predictions. A spae is a prediction or foretelling. We'll foretell you what your phage is doing! - GitHub - linsalrob/sphae: NEW!!! Phage annotations and prediction...
https://github.com/linsalrob/sphae
about 2 years ago
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Attending
#COMBINE23
and
#abacbs23
symposium in Brisbane this week. A special thanks to COMBINE committee and South Australian immunoGENomics Cancer Institute for the student travel award.
about 2 years ago
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Bhavya N P
Jolene Ramsey
about 2 years ago
#MicroSky
#phagesky
abstract submission for
#VoM2024
is open & guest for live
#TWiV
This Week in Virology
@microbetv.bsky.social
#podcast
will be chosen from abstracts submitted by Feb 16 at
www.vom2024.org/cfa
. Time to get writing.
add a skeleton here at some point
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reposted by
Bhavya N P
Rob Edwards
about 2 years ago
"Virus discovery is new ammunition for tackling 'germ warfare' in humans" work from
@npbhavya.bsky.social
#phagesky
#microsky
phys.org/news/2023-11...
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Virus discovery is new ammunition for tackling 'germ warfare' in humans
An international research team has identified potential new 'weapons' in the 'arms race' for new antibiotics and possible future therapies for a more balanced gut microbiome and human health.
https://phys.org/news/2023-11-virus-discovery-ammunition-tackling-germ.html
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reposted by
Bhavya N P
Chenxin Li, PhD
about 2 years ago
Not enough people know about
bioicons.com
Open source vector graphics. Free alternatives to BioRender.
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reposted by
Bhavya N P
Susie Grigson
about 2 years ago
Our latest phage paper has been published in Clinical Infectious Diseases! We walk through the bioinformatic methods we use to identify and characterise phages for phage therapy. Check it out:
academic.oup.com/cid/article/...
@linsalrob.bsky.social
@npbhavya.bsky.social
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Knowing and Naming: Phage Annotation and Nomenclature for Phage Therapy
Abstract. Bacteriophages, or phages, are viruses that infect bacteria shaping microbial communities and ecosystems. They have gained attention as potential agen
https://academic.oup.com/cid/article/77/Supplement_5/S352/7334995?searchresult=1
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This work wouldn’t have been possible without all our collaborators. In this research we show that crassphages belonging to multiple families can infect the same bacterial host, potentially interacting with the TonB-dependent receptors on their surface.
www.microbiologyresearch.org/content/jour...
add a skeleton here at some point
about 2 years ago
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