Hier ein Beispiel für eine berühmte Simulation mit einem #Analogrechner: Das Modell der #Insulin-Glukose-Homöostase von Bolie (1960). Dieses Modell hatte einen enormen Einfluss auf unser Verständnis des #Diabetes mellitus und lässt sich mit modernen Analogrechnern jetzt wieder direkt reproduzieren.

#SimulAdren underwent a major upgrade. Version 2.0 introduces significant new features, e.g., support for different models, initial conditions, first-order delay kinetics (ASIA elements), and model continuation. simuladren.sourceforge.io doi.org/10.5281/zeno... doi.org/10.5281/zeno...

#SimulAdren, based on #CyberUnits Bricks, has been upgraded to version 1.3 (Green Lizard). This version introduces functionality to save plots and the block diagram of the information processing structure as graphics files. simuladren.sourceforge.io doi.org/10.5281/zeno... doi.org/10.5281/zeno...

#SimulAdren is a simulation program for the #hypothalamus - #pituitary - #adrenal feedback control, an essential physiological motif. It is written in #Object_Pascal and helps to understand life-threatening diseases.

#Simuladren, a simulator for the #HPA axis based on #CyberUnits Bricks, has been updated to version 1.2. This upgrade introduces support for XML files according to #MIASE and #MIRIAM guidelines and high-res displays on Windows. simuladren.sourceforge.io doi.org/10.5281/zeno...

#SimulAdren has been released in version 1.1. This cross-platform simulator of the corticotropic feedback loop (hypothalamus-pituitary-adrenal or #HPA axis) is based on the #CyberUnits Bricks class library. doi.org/10.5281/zeno... doi.org/10.5281/zeno... simuladren.sf.net

For a completely different task, simulating biological feedback loops, #Object_Pascal generates the fastest code. It is not only faster than that of interpreted languages (S/R and Python) but even outperforms fast compiled languages (C++ and Swift). #Pascal #programming doi.org/10.14201/adc...

In scientific computing, speed is critical when choosing a programming language. Additionally, given limited resources for funding and the challenges of climate change, memory and energy efficiency are important as well. #Pascal is in the Pareto-optimal set of these goals. doi.org/10.1016/j.sc...