How best to treat invasive aspergillosis? @pascalisid.bsky.social reviewing key clinical studies informing this choice - important to monitor vori levels , NB: AmB <vori=isavu @idweek.bsky.social #IDWeek2025 #TxID #IDSky

Please join us this Monday 8-9 am at IDWeek. Difficult-to-treat mold infections. Dimitrios Farmakiotis will be discussing treatment of mucormycosis. I will be discussing aspergillosis.

There’s now an app for all things fungi 🦠🍄 Dr. Matthew Pullen, Assistant Professor at the University of Minnesota, helped launch Dr Fungus—a free app that brings the trusted resource to your phone. Explore fungal infections, antifungal treatments, and case-based learning—all in one place.

🆕 MMWR: In NYC, NDM-CRE just surpassed KPC-CRE for the first time. And nearly 75% of these cases had no long-term care facility link This is a changing landscape of antibiotic resistance - happening across US #IDSky 📄: www.cdc.gov/mmwr/volumes...

Detection of Mucorales antigen in BAL samples using a newly developed lateral-flow device A Mucorales antigen test is sorely needed This one had Sn of 76.92%, Sp of 75.51%, respectively, PPV 45.45%, and a NPV 92.5% (Not good enough but could augment qPCR) journals.asm.org/doi/10.1128/...

Join us for a panel discussion on “Leveraging Partnerships to Fight Fungal Diseases” June 19 2.55-3.25 pm @ASMicrobiology Dallas Smith @CDCgov Sean Zhang, Fungal Diagnostics Laboratory Consortium Rob Purdie, MYCology Advocacy, Research & Education Zachary Rubin @lapublichealth Me @MSG_ERC

Visited the historic city of Philadelphia to attend the American Board of Internal Medicine (ABIM) New Governance Orientation. Looking forward to serving on the Infectious Disease Approval Committee. Of the profession, for the public

Synthesis of the available literature on the use of CMV-specific T-cell therapy in adult and pediatric HSCT and SOT recipients. Several patients on concurrent antivirals, which confounded the effectiveness of VSTs @CIDJournal @transplantidnet.bsky.social academic.oup.com/cid/advance-...

Dr. Jeniel Nett discussing biofilm at the 2025 Scientific Meeting on Candida auris @msgerc.bsky.social

High Kaposi sarcoma-associated herpesvirus seroprevalence in donors and recipients with HIV, particularly among MSM. Reassuringly, disease was rare. @transplantidnet.bsky.social academic.oup.com/cid/advance-...

In a phase 3 clinical trial, pemivibart provided prophylactic efficacy against COVID-19 in immunocompromised patients and individuals at risk for exposure. Four of 623 participants experienced anaphylactic reactions @transplantidnet.bsky.social academic.oup.com/cid/advance-...

Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) Fluco-R C parapsilosis ⬆️ from 8.2% to 20.3% in BCx isolates tested @ Mayo Jack McHugh ... @pascalisid.bsky.social academic.oup.com/jid/advance-...

This #TransDayofVisibility 🏳️‍⚧️ Please know: We see you, & we will continue to fight for you.

ID Grand Rounds. I discussed the following: - ONE Health - Aspergillus urine antigen - Giant magnetoresistance-enabled PCR - Rezafungin for prevention in bone marrow transplant - Ibrexafungerp (FURI) - Olorofim (Study 32) - Our experience with fosmanogepix

In rare cases, vaping-associated lung injury (EVALI) may lead to irreversible damage requiring lung transplantation

Can filgrastim precipitate organ rejection ?

We used Giant Magnetoresistance to diagnose invasive fungal infection. The assay has the potential to detect trace amounts of fungal DNA in serum academic.oup.com/ofid/article...

Aspergillus pseudodeflectus belongs to the Aspergillus section Usti. Can be multidrug resistant (similar to calidoustus) - Learning something every day!

Highly recommended! Fungal Update: Mycology 2025 in London. This a pic from last year… @germhuntermd.bsky.social

Recommendation to screen, even though no cases of TB transmission reported after allogeneic stem cell transplant

Remember that fosmanogepix can cause neurotoxicity (approx 10%)

Generative AI platforms for clinical conversations create mediocre medical notes

Mayo Clinic remains committed to Diversity and Inclusion

You are all familiar with immune checkpoint inhibitor-associated pneumonitis. Adagrasib inhibits KRAS G12C and is used to treat non-small cell lung cancer. It can also be associated with pneumonitis. Need to rule out infection first. Discontinue adagrasib and treat with corticosteroids.

Mayo Clinic remains committed to Diversity and Inclusion

We had a great conference. Looking forward to Mayo Clinic Infectious Disease Updates 2026 in Maui!

We had a great conference. Looking forward to Mayo Clinic Infectious Disease Updates 2026 in Maui!

Mayo Clinic CME Infectious Disease Updates. Successful session on Infections in Hematology. We discussed advances in the diagnosis and treatment of fungal infection, duration of treatment for febrile neutropenia, complications of CAR-T cell therapy, fusariosis and breakthrough aspergillosis.

Mayo Clinic CME Infectious Disease Updates. Successful session on Infections in Hematology. We discussed advances in the diagnosis and treatment of fungal infection, duration of treatment for febrile neutropenia, complications of CAR-T cell therapy, fusariosis and breakthrough aspergillosis.

Coming soon to a city near you… bonus points if you can name the soon to be un-eradicated vaccine-preventable diseases. #IDSky

Aspergillus ustus tracheobronchitis. Necrotic debris within the airways. One month post-transplant for ILD. Breakthrough on posaconazole prophylaxis (level 832 ng/mL). Susceptibilities are pending. How would you treat?

Aspergillus was named by Pier Antonio Micheli, an Italian priest and biologist. The molds resembled an aspergillum, a holy water sprinkler.