Martin Schaefer (@martinschaefer.bsky.social)

Happy to share our new article in @narjournal.bsky.social! We present Methodical, a computational approach to systematically map regions where DNA methylation most strongly correlates with transcription refining our understanding of gene regulation in normal and tumor tissues doi.org/10.1093/nar/...

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Systematic identification of regions where DNA methylation is correlated with transcription refines regulatory logic in normal and tumour tissues Abstract. DNA methylation at gene promoters is generally considered to be associated with transcriptional repression in vertebrates. However, lack of a cle https://academic.oup.com/nar/article-abstract/doi/10.1093/nar/gkaf949/8268404?utm_source=advanceaccess&utm_campaign=nar&utm_medium=email